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1949-53 Adelaide outbreak
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== Findings == As with other epidemics, no virus was isolated and there was an absence of abnormal findings in [[cerebrospinal fluid]]<ref name=":12" /> However, there were some interesting finding in animal studies. Pellew collected throat washings, feces, and cerebrospinal fluid from a subset of patients and inoculated rhesus monkeys, mice, and hen eggs. Several monkeys displayed sluggishness and subnormal body temperature. One died. On autopsy, two monkeys showed red spots along the sciatic nerves and microscopic damage:<blockquote>"There were lesions in the nerve roots and in the sciatic nerves. In the nerve roots close to their point of exit from the spinal canal there was pronounced infiltration with lymphocytes and mononuclear cells, and in a percentage of the nerve fibres were found vacuoles in the myelin sheaths and axon swellings. In the sciatic nerves there were small localized infiltrations with inflammatory cells associated with exudation of a few red blood corpuscles. The only abnormality in the skeletal muscle was the presence of sarcoporidiosis in all sections from one animal; but examination of the heart muscle of the monkey which had died showed severe myocarditis with widespread infiltration mainly with lymphocytes and mononuclear cells."<ref name=":2" /></blockquote>
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