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1955 Dalston outbreak
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Beginning in January 1955, an outbreak of disease thought to be consistent with [[myalgic encephalomyelitis]]occurred, centered around the village of Dalston in Cumbria, England and affected 233 people (14% of the practice population). Males and females were equally affected. (https://www.jstor.org/stable/4457588?seq=1#page_scan_tab_contents) An epidemiological study of the outbreak was published by Dr. [[A. L. Wallis]], a general practitioner that covered the areas concerned.<ref name=":0">{{Cite book | title = An investigation into an unusual disease seen in epidemic and sporadic form in a general practice in Cumberland in 1955 and subsequent years, M.D. Thesis | last = Wallis | first = A.L. | publisher = University of Edinburgh| date = 1957|isbn=|location= | pages = }}</ref> == Onset == == Symptoms == * [[lymphadenopathy]] * [[hepatosplenomegaly]] * abnormal [[Lymphocyte|lymphocytes]] * [[Paresthesia|Paresthesias]] * blurred vision * vertigo * depression as a significant problem * [[myalgia]] * muscle weakness (especially in lower limbs) * joint pain * cognitive dysfunction (loss of concentration manifested, inability to read, knit) * locomotor dysfunction * reticuloendothelial involvement * ulnar neuropathies == Findings == Wallis initially thought the infection was glandular fever, but tests came back negative.<ref name=":0" /> == Epidemiology == The attack rate during the epidemic was 13.9%.<ref name=":0" /> Endemic cases continued to appear several years after the initial outbreak and incidence of the disease spread to surrounding villages. == Prognosis == There were no fatalities. Relapses occurred in a proportion of those infected; in some cases, several relapses occurred over a period of months, symptoms being minimal or absent between the recurrences.<ref name=":0" /> "Recurrences of symptoms of the disease became a well marked feature of the epidemic, and it was noted that in some instances a contact of the primary host, who was having a recurrent attack, would develop the typical disease, suggesting, therefore, that, at the time of the recurrent attack, the host was again infectious."<ref name=":0" /> == See also == * [[Epidemic myalgic encephalomyelitis]] * [[List of myalgic encephalomyelitis and chronic fatigue syndrome outbreaks]] ==Learn more== ==References== {{Reflist}} [[Category:History]] [[Category:Outbreaks]] [[Category:Outbreaks in the 1950s]] [[Category:Outbreaks in the United Kingdom]]
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