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1980-81 Ayrshire outbreak
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During the period between January 1980 and June 1981, an outbreak of [[myalgic encephalomyelitis|ME]] was documented in a rural practice in '''Ayrshire, Scotland.''' Details of the outbreak were documented and published by K. G. Fegan.<ref name="Fegan, 1983" /> A total of 22 patients with suspected [[myalgic encephalomyelitis]] were seen (16 females and 6 males), ranging in age from 6 to 53 years. The outbreak presented either as an acute or a subacute illness with protean symptoms. The most characteristic symptom was [[Chronic fatigue|extreme exhaustion]], particularly after [[exercise]] or any degree of [[Emotional dysfunction|emotional]] or [[Cognitive dysfunction|mental strain]]. Other symptoms reported included [[headache]], [[vertigo]], increased [[Hyperacusis|sensitivity to normal sounds]], [[tinnitus]], chest pains on [[exertion]] (often with palpitations), [[anxiety]], [[depression]], [[Sleep dysfunction|sleep pattern disturbances]], [[Myalgia|muscle aches and pains]], coarse muscular twitchings, odd paraesthesiae, [[diarrhea]], loss of appetite and [[alcohol intolerance]]. (''See:'' [[Post-exertional malaise]].) In 67% of the cases, there was a relapsing course. Routine laboratory findings were normal.<ref name="Fegan, 1983" /> A large percentage of patients affected by this outbreak were found to have elevated antibody titers to [[coxsackie B]] virus; 59% of the ME population had a titer greater than 512 implying a recent [[coxsackie B]] virus infection compared to 4% of the population residing in the surrounding area.<ref name="Fegan, 1983" /> ==Learn more== *[http://bjgp.org/content/bjgp/33/251/335.full.pdf "Myalgic encephalomyelitis β report of an epidemic," by Fegan, et al]<ref name="Fegan, 1983" /> ==See also== *[[Epidemic myalgic encephalomyelitis]] *[[List of myalgic encephalomyelitis and chronic fatigue syndrome outbreaks]] ==Learn more== ==References== <references> <ref name="Fegan, 1983">{{Citation | last1 = Fegan | first1 = K.G. | author-link1 = | last2 = Behan | first2 = P.O. | author-link2 = Peter Behan | last3 =Bell | first3 = E.J. | author-link3 = | title = Myalgic encephalomyelitis β report of an epidemic | journal = Journal of the Royal College of General Practitioners | volume = 33 | issue =251 | page = 335β337 | date = 1983 | url = http://bjgp.org/content/bjgp/33/251/335.full.pdf }}</ref> </references> [[Category:History]] [[Category:Outbreaks]] [[Category:Outbreaks in the 1980s]] [[Category:Outbreaks in the United Kingdom]]
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