Abnormal neurovascular coupling: Difference between revisions

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'''Neurovascular coupling''' (NVC) refers to the "regulation of cerebral blood flow to match brain activity, which is critically important for normal brain function".<ref name="uscgrantpress">{{Cite web|url=https://www.usc.edu.au/explore/usc-news-exchange/news-archive/2019/december/usc-research-to-diagnose-invisible-illness-faster|title=USC research to diagnose ‘invisible’ illness faster|last=|first=|authorlink=|last2=|first2=|authorlink2=|date=Dec 2019|website=University of the Sunshine Coast|language=en|archive-url=|archive-date=|dead-url=|access-date=2019-12-09}}</ref> '''Abnormal neurovascular coupling''' is a hypothesis being investigated to find out if it is underpinning cause of [[chronic fatigue syndrome]]. In 2019, Dr [[Zack Shan]] was awarded a grant to research neurovascular coupling in CFS.<ref name="uscgrantpress" />
'''Neurovascular coupling''' (NVC) refers to the "regulation of cerebral blood flow to match brain activity, which is critically important for normal brain function".<ref name="uscgrantpress">{{Cite web | url = https://www.usc.edu.au/explore/usc-news-exchange/news-archive/2019/december/usc-research-to-diagnose-invisible-illness-faster | title = USC research to diagnose ‘invisible’ illness faster | last = | first = | author-link = | date = Dec 2019 | website = University of the Sunshine Coast|language=en|archive-url=|archive-date=|url-status= | access-date = 2019-12-09}}</ref> '''Abnormal neurovascular coupling''' is a hypothesis being investigated to find out if it is underpinning cause of [[chronic fatigue syndrome]]. In 2019, Dr [[Zack Shan]] was awarded a grant to research neurovascular coupling in CFS.<ref name="uscgrantpress" />


==Theory==
==Theory==
According to Stewart et al. (2012) the cerebral perfusion may be contributing to the [[brain fog]] (neurocognitive dysfunction) found in patients with CFS may [[POTS]].<ref name="Stewart2012">{{Cite journal|last=Stewart|first=Julian M.|author-link=Julian Stewart|last2=Medow|first2=Marvin S.|author-link2=Marvin Medow|last3=Messer|first3=Zachary R.|author-link3=Zachary Messer|last4=Baugham|first4=Ila L.|author-link4=Ila Baugham|last5=Terilli|first5=Courtney|author-link5=Courtney Terilli|last6=Ocon|first6=Anthony J.|author-link6=Anthony Ocon|last7=|first7=|last8=|first8=|date=2011-12-16|title=Postural neurocognitive and neuronal activated cerebral blood flow deficits in young chronic fatigue syndrome patients with postural tachycardia syndrome|url=https://www.physiology.org/doi/full/10.1152/ajpheart.00994.2011|journal=American Journal of Physiology-Heart and Circulatory Physiology|volume=302|issue=5|pages=H1185–H1194|doi=10.1152/ajpheart.00994.2011|issn=0363-6135|pmc=PMC3311460|pmid=22180650|access-date=|quote=|via=}}</ref><ref name="Oncon2013">{{Cite journal|last=Ocon|first=Anthony James|author-link=Anthony Ocon|last2=|first2=|author-link2=|last3=|first3=|author-link3=|last4=|first4=|author-link4=|last5=|first5=|author-link5=|last6=|first6=|author-link6=|last7=|first7=|last8=|first8=|date=Apr 5, 2013|title=Caught in the thickness of brain fog: exploring the cognitive symptoms of Chronic Fatigue Syndrome|url=https://www.frontiersin.org/articles/10.3389/fphys.2013.00063/full|journal=Frontiers in Physiology|language=English|volume=4|issue=63|pages=|doi=10.3389/fphys.2013.00063|issn=1664-042X|pmc=PMC3617392|pmid=23576989|access-date=|quote=|via=}}</ref>
According to Stewart et al. (2012) the cerebral perfusion may be contributing to the [[brain fog]] (neurocognitive dysfunction) found in patients with CFS may [[Postural orthostatic tachycardia syndrome|POTS]].<ref name="Stewart2012">{{Cite journal | last = Stewart | first = Julian M. | author-link = Julian Stewart | last2 = Medow | first2 = Marvin S. | author-link2 = Marvin Medow | last3 = Messer | first3 = Zachary R. | author-link3 = Zachary Messer | last4 = Baugham | first4 = Ila L. | author-link4 = Ila Baugham | last5 = Terilli | first5 = Courtney | author-link5 = Courtney Terilli | last6 = Ocon | first6 = Anthony J. | author-link6 = Anthony Ocon | date = 2011-12-16 | title = Postural neurocognitive and neuronal activated cerebral blood flow deficits in young chronic fatigue syndrome patients with postural tachycardia syndrome | url =https://www.physiology.org/doi/full/10.1152/ajpheart.00994.2011 | journal = American Journal of Physiology-Heart and Circulatory Physiology | volume = 302 | issue = 5 | pages = H1185–H1194|doi=10.1152/ajpheart.00994.2011|issn=0363-6135|pmc = 3311460|pmid=22180650|access-date=|quote=|via=}}</ref><ref name="Oncon2013">{{Cite journal | last = Ocon | first = Anthony James | author-link = Anthony Ocon | date = Apr 5, 2013 | title = Caught in the thickness of brain fog: exploring the cognitive symptoms of Chronic Fatigue Syndrome | url =https://www.frontiersin.org/articles/10.3389/fphys.2013.00063/full | journal = Frontiers in Physiology|language=English | volume = 4 | issue = 63 | pages = |doi=10.3389/fphys.2013.00063|issn=1664-042X| pmc = 3617392|pmid=23576989|access-date=|quote=|via=}}</ref>
 
==ME/CFS ==


==Evidence==
==Evidence==

Latest revision as of 13:21, April 3, 2023

Neurovascular coupling (NVC) refers to the "regulation of cerebral blood flow to match brain activity, which is critically important for normal brain function".[1] Abnormal neurovascular coupling is a hypothesis being investigated to find out if it is underpinning cause of chronic fatigue syndrome. In 2019, Dr Zack Shan was awarded a grant to research neurovascular coupling in CFS.[1]

Theory[edit | edit source]

According to Stewart et al. (2012) the cerebral perfusion may be contributing to the brain fog (neurocognitive dysfunction) found in patients with CFS may POTS.[2][3]

ME/CFS[edit | edit source]

Evidence[edit | edit source]

Treatment[edit | edit source]

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]