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Ampligen
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==Notable studies== *1994, Ampligen inhibits human herpesvirus-6 in vitro.<ref name="Ablashi, 1994" /> *1994, A controlled clinical trial with a specifically configured RNA drug, poly(I).poly(C12U), in chronic fatigue syndrome<ref name="Strayer,1994" /> *2004, The Interferon Inducer Ampligen [Poly(I)-Poly(C12U)] Markedly Protects Mice against Coxsackie B3 Virus-Induced Myocarditis<ref>{{Cite journal | last = Padalko | first = E. | last2 = Nuyens | first2 = D. | last3 = De Palma | first3 = A. | last4 = Verbeken | first4 = E. | last5 = Aerts | first5 = J.L. | last6 = De Clercq | first6 = E. | last7 = Carmeliet | first7 = P. | last8 = Neyts | first8 = J. | date = 2004-01-01 | title = The Interferon Inducer Ampligen [Poly(I)-Poly(C12U)] Markedly Protects Mice against Coxsackie B3 Virus-Induced Myocarditis | url =http://aac.asm.org/cgi/doi/10.1128/AAC.48.1.267-274.2004 | journal = Antimicrobial Agents and Chemotherapy|language=en | volume = 48 | issue = 1 | pages = 267β274|doi=10.1128/AAC.48.1.267-274.2004|issn=0066-4804|pmc=310159|pmid=14693549}}</ref> - [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC310159/ (Full Text)] *1995, Long Term Improvements in Patients with Chronic Fatigue Syndrome Treated with Ampligen<ref name="Strayer,1995" /> *2012, A double-blind, placebo-controlled, randomized, clinical trial of the TLR-3 agonist rintatolimod in severe cases of chronic fatigue syndrome.<ref name="Strayer, 2012" /> *2015, [http://annals.org/article.aspx?articleid=2322801 Treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Systematic Review for a National Institutes of Health Pathways to Prevention Workshop] *2016, [https://www.ncbi.nlm.nih.gov/pubmed/27045557 Efficacy of rintatolimod in the treatment of chronic fatigue syndrome/ myalgic encephalomyelitis (cfs/me)]<ref name=":4" /> *2020, Effect of disease duration in a randomized Phase III trial of rintatolimod, an immune modulator for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome<ref name="Strayer2020">{{Cite journal | title = Effect of disease duration in a randomized Phase III trial of rintatolimod, an immune modulator for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome | date = 2020-10-29 | url = https://dx.plos.org/10.1371/journal.pone.0240403 | journal = PLOS ONE | volume = 15 | issue = 10| pages = e0240403 | last = Strayer | first = David R. | author-link = David Strayer | last2 = Young | first2 = Diane | author-link2 = | last3 = Mitchell | first3 = William M. | author-link3 = William Mitchell|language=en|doi=10.1371/journal.pone.0240403|pmc=PMC7595369|pmid=33119613|access-date=|issn=1932-6203|quote=|via=}}</ref> - [https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0240403 (Full text)]
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