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[[File:BCell EBV.png|thumb|B cell shedding Epstein-Barr virus]] '''B cells,''' also known as B [[lymphocyte]]s, are a type of [[white blood cell]]. They function in the [[humoral immunity]] component of the [[adaptive immune system]] by secreting antibodies. ==Chronic fatigue syndrome== ==Notable studies== *2018, [[CD24]] expression and B cell maturation shows a novel link with energy metabolism: potential implications for patients with ME/CFS [https://www.frontiersin.org/articles/10.3389/fimmu.2018.02421/full (Full text)] *2016, Extended B cell phenotype in patients with [[ME/CFS|Myalgic Encephalomyelitis/Chronic Fatigue Syndrome]]: A cross-sectional study<ref name="Mensah, 2016" /> [https://onlinelibrary.wiley.com/doi/full/10.1111/cei.12749 (Full Text)] | [[Jonathan Edwards]] comments on: Extended B-cell phenotype in patients with ME/CFS: A cross-sectional study [http://forums.phoenixrising.me/index.php?threads/extended-b-cell-phenotype-in-patients-with-me-cfs-a-cross-sectional-study.41743/#post-674305 (Link)] *2015, [http://www.ncbi.nlm.nih.gov/m/pubmed/26399744/ Antibodies to Ξ² adrenergic and muscarinic cholinergic receptors in patients with Chronic Fatigue Syndrome] *2015, [http://www.ncbi.nlm.nih.gov/m/pubmed/26132314/ B-Lymphocyte Depletion in Myalgic Encephalopathy/ Chronic Fatigue Syndrome. An Open-Label Phase II Study with Rituximab Maintenance Treatment] *2013, Altered functional B cell subset populations in patients with [[chronic fatigue syndrome]] compared to healthy controls.<ref name="Bradley, 2013" /> [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719933/ (Full Text)] *2011, Benefit from B-lymphocyte depletion using the anti-CD20 antibody rituximab in chronic fatigue syndrome. A double-blind and placebo-controlled study [http://www.ncbi.nlm.nih.gov/m/pubmed/22039471/ (Full text)] *2009, [http://www.ncbi.nlm.nih.gov/m/pubmed/19566965/ Clinical impact of B-cell depletion with the anti-CD20 antibody rituximab in chronic fatigue syndrome: a preliminary case series] ==Learn more== *[https://en.wikipedia.org/wiki/B_cell Wikipedia - B cell] *[https://www.youtube.com/watch?v=2DFN4IBZ3rI&feature=youtu.be Crash Course - The Immune System Part 2] (Humoral immunity & B cells) *2016, [http://www.ukrituximabtrial.org/Rituximab%20news-Mar16%2001.htm First Paper Published from IiME-funded Research at UCL - Layman's Summary] ([[Invest in ME]]) ==See also== *[[Rituximab]] *[[Ocrelizumab]] *[[Adaptive immune system]] ==References== <references> <ref name="Bradley, 2013">{{Citation | last1 = Bradley | first1 = AS | author-link1 = | last2 = Ford | first2 = B | author-link2 = | last3 = Bansal | first3 = Amolak | author-link3 = Amolak Bansal | title = Altered functional B cell subset populations in patients with chronic fatigue syndrome compared to healthy controls | journal = Clinical and Experimental Immunology | volume = 172 | issue = 1 | page = 73β80 | date = 2013 | pmid = | doi = 10.1111/cei.12043 }}</ref> <ref name="Mensah, 2016">{{Citation | last1 = Mensah | first1 = Fane | author-link1 = Fane Mensah | last2 = Bansal | first2 = Amolak | author-link2 = Amolak Bansal | last3 = Berkovitz | first3 = Saul | author-link3 = Saul Berkovitz | last4 = Sharma | first4 = Arti | author-link4 = | last5 = Reddy | first5 = Venkat | author-link5 = Venkat Reddy | last6 = Leandro | first6 = Maria | author-link6 = Maria Leandro | last7 = Cambridge | first7 = Geraldine| author-link8 = Geraldine Cambridge | title = Extended B cell phenotype in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A cross-sectional study | journal = Clinical and Experimental Immunology | volume = 184 | issue = 2 | page = 237-247 | date = 2016 | pmid = | doi = 10.1111/cei.12749 }}</ref> </references> [[Category:Body systems]] [[Category:Immune cells]] [[Category:Immunology]] [[Category:Blood components]]
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