Carmen Scheibenbogen: Difference between revisions
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==Diagnostic test== | ==Diagnostic test== | ||
Professor Scheibenbogen helped create the [[CellTrend Diagnostic Test]] which may help identify a subset of 20-30% of all patients with [[ME/CFS]]. These patients have elevated levels of three auto-antibodies, i.e., against the b2-adrenergic receptor, against the muscarinic cholinergic receptor 3 (M3) and against the muscarinic cholinergic receptor 4 (M4).<ref> | Professor Scheibenbogen helped create the [[CellTrend Diagnostic Test]] which may help identify a subset of 20-30% of all patients with [[ME/CFS]]. These patients have elevated levels of three auto-antibodies, i.e., against the b2-adrenergic receptor, against the muscarinic cholinergic receptor 3 (M3) and against the muscarinic cholinergic receptor 4 (M4).<ref>{{Cite web|url=https://www.celltrend.de/en/pots-cfs-me-crps.html|title=POTS - CFS/ME - CRPS|website=CellTrend Luckenwalde|language=en-US|access-date=2020-02-18}}</ref> | ||
==Awards== | ==Awards== | ||
*2016 Ramsay Award Program grant recipient, sponsored by the [[Solve ME/CFS Initiative]] for [[Autoimmunity |Autoimmune]] Signature in [[ME/CFS|myalgic encephalomyelitis/chronic fatigue syndrome]]. This grant was shared with [[Madlen Löbel]], Charité Universitätsmedizin Berlin.<ref>{{Cite web|url=https://solvecfs.org/2016-ramsay-award-program-results/|title=2016 Ramsay Award Program Results|website=Solve ME/CFS Initiative|language=en-US|access-date=2019-11-14}}</ref> | *2016 [[Ramsay Award]] Program grant recipient, sponsored by the [[Solve ME/CFS Initiative]] for [[Autoimmunity |Autoimmune]] Signature in [[ME/CFS|myalgic encephalomyelitis/chronic fatigue syndrome]]. This grant was shared with [[Madlen Löbel]], Charité Universitätsmedizin Berlin.<ref>{{Cite web|url=https://solvecfs.org/2016-ramsay-award-program-results/|title=2016 Ramsay Award Program Results|website=Solve ME/CFS Initiative|language=en-US|access-date=2019-11-14}}</ref> | ||
*2017 Ramsay Award Program grant was awarded to a team comprised of Dr. Carmen Scheibenbogen and Dr. [[Franziska Sotzny]] of Charité Universitätsmedizin Berlin, sponsored by the [[Solve ME/CFS Initiative]] for researching immunometabolism of [[T cell]]s and monocytes in [[ME/CFS]].<ref>{{Cite web|url=https://solvecfs.org/2017-ramsay-award-program-results/|title=2017 Ramsay Award Program Results|website=Solve ME/CFS Initiative|language=en-US|access-date=2019-11-14}}</ref> | *2017 [[Ramsay Award]] Program grant was awarded to a team comprised of Dr. Carmen Scheibenbogen and Dr. [[Franziska Sotzny]] of Charité Universitätsmedizin Berlin, sponsored by the [[Solve ME/CFS Initiative]] for researching immunometabolism of [[T cell]]s and monocytes in [[ME/CFS]].<ref>{{Cite web|url=https://solvecfs.org/2017-ramsay-award-program-results/|title=2017 Ramsay Award Program Results|website=Solve ME/CFS Initiative|language=en-US|access-date=2019-11-14}}</ref> | ||
==Notable studies== | ==Notable studies== |
Revision as of 21:04, February 18, 2020
Professor Doctor Carmen Scheibenbogen is an Internal Medicine physician, ME/CFS doctor and the Professor for Immunology and Deputy Chair, Institute of Medical Immunology, at the University Hospital Charité in Berlin, Germany. Her research focuses on the role of Epstein-Barr virus (EBV), particularly the characterization of EBV specific B cell and T cell response and the enhanced antibody response against EBV peptides in myalgic encephalomyelitis (ME) versus healthy controls.[1]
EUROMENE[edit | edit source]
Professor Scheibenbogen is the Leader of the Biomarkers Working Group of EUROMENE, a European Union, COST Action CA15111, not-for-profit research organization committed to tackling the cause and treatment for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.[2]
Diagnostic test[edit | edit source]
Professor Scheibenbogen helped create the CellTrend Diagnostic Test which may help identify a subset of 20-30% of all patients with ME/CFS. These patients have elevated levels of three auto-antibodies, i.e., against the b2-adrenergic receptor, against the muscarinic cholinergic receptor 3 (M3) and against the muscarinic cholinergic receptor 4 (M4).[3]
Awards[edit | edit source]
- 2016 Ramsay Award Program grant recipient, sponsored by the Solve ME/CFS Initiative for Autoimmune Signature in myalgic encephalomyelitis/chronic fatigue syndrome. This grant was shared with Madlen Löbel, Charité Universitätsmedizin Berlin.[4]
- 2017 Ramsay Award Program grant was awarded to a team comprised of Dr. Carmen Scheibenbogen and Dr. Franziska Sotzny of Charité Universitätsmedizin Berlin, sponsored by the Solve ME/CFS Initiative for researching immunometabolism of T cells and monocytes in ME/CFS.[5]
Notable studies[edit | edit source]
- 2014, Deficient EBV-Specific B- and T-Cell Response in Patients with Chronic Fatigue Syndrome[6] - (Full Text)
- 2015, Frequent IgG subclass and mannose binding lectin deficiency in patients with chronic fatigue syndrome[7] - (Full Text)
- 2015, Polymorphism in COMT is associated with IgG3 subclass level and susceptibility to infection in patients with chronic fatigue syndrome[8] - (Full Text)
- 2016, Antibodies to β adrenergic and muscarinic cholinergic receptors in patients with Chronic Fatigue Syndrome[9] - (Full Text)
- 2017, Serological profiling of the EBV immune response in Chronic Fatigue Syndrome using a peptide microarray[10] -(Full Text)
- 2017, The European ME/CFS Biomarker Landscape project: an initiative of the European network EUROMENE[11] - (Full Text)
- 2018, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome – Evidence for an autoimmune disease[12] - (Full Text)
- 2018, Immunoadsorption to remove ß2 adrenergic receptor antibodies in Chronic Fatigue Syndrome CFS/ME[13] - (Full Text)
- 2018, The expression signature of very long non-coding RNA in myalgic encephalomyelitis/chronic fatigue syndrome[14] - (Full Text)
- 2018, Prevalence and incidence of myalgic encephalomyelitis/chronic fatigue syndrome in Europe—the Euro-epiME study from the European network EUROMENE: a protocol for a systematic review[15] - (Full text)
- 2018, Chronic viral infections in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)[16] - (Full text)
Clinic location[edit | edit source]
- Charité University Medicine, Berlin, Germany
Talks and interviews[edit | edit source]
- 2018, Talk "Chronic Fatigue Syndrome" for General Practitioners
- 2014, Speaker at the 9th Invest in ME International ME Conference DVD available
Online presence[edit | edit source]
See also[edit | edit source]
Learn more[edit | edit source]
References[edit | edit source]
- ↑ "Invest in ME Research - International ME Conferences and Colloquiums Home Page". investinme.org. Retrieved November 14, 2019.
- ↑ "Action CA15111". COST. Retrieved November 14, 2019.
- ↑ "POTS - CFS/ME - CRPS". CellTrend Luckenwalde. Retrieved February 18, 2020.
- ↑ "2016 Ramsay Award Program Results". Solve ME/CFS Initiative. Retrieved November 14, 2019.
- ↑ "2017 Ramsay Award Program Results". Solve ME/CFS Initiative. Retrieved November 14, 2019.
- ↑ Loebel, Madlen; Strohschein, Kristin; Giannini, Carolin; Koelsch, Uwe; Bauer, Sandra; Doebis, Cornelia; Thomas, Sybill; Unterwalder, Nadine; von Baehr, Volker; Reinke, Petra; Knops, Michael; Hanitsch, Leif G.; Meisel, Christian; Volk, Hans-Dieter; Scheibenbogen, Carmen (January 15, 2014), "Deficient EBV-Specific B- and T-Cell Response in Patients with Chronic Fatigue Syndrome", PLoS One, doi:10.1371/journal.pone.0085387
- ↑ Guenther, Sabrina; Loebel, Madlen; Mooslechner, Agnes A; Knops, Michael; Hanitsch, Leif G; Grabowski, Patricia; Wittke, Kirsten; Meisel, Christian; Unterwalder, Nadine; Volk, Hans-Dieter; Scheibenbogen, Carmen (2015), "Frequent IgG subclass and mannose binding lectin deficiency in patients with chronic fatigue syndrome", Human Immunology, 76 (10): 729-35, doi:10.1016/j.humimm.2015.09.028
- ↑ Loebel, Madlen; Mooslechner, Agnes Anna; Bauer, Sandra; Günther, Sabrina; Letsch, Anne; Hanitsch, Leif G; Grabowski, Patricia; Meisel, Christian; Volk, Hans-Dieter; Scheibenbogen, Carmen (2015), "Polymorphism in COMT is associated with IgG3 subclass level and susceptibility to infection in patients with chronic fatigue syndrome", Journal of Translational Medicine, 13, doi:10.1186/s12967-015-0628-4
- ↑ Loebel, M; Grabowski, P; Heidecke, H; Bauer, S; Hanitsch, LG; Wittke, K; Meisel, C; Reinke, P; Volk, H; Fluge, Ø; Mella, O; Scheibenbogen, C (2016), "Antibodies to β adrenergic and muscarinic cholinergic receptors in patients with Chronic Fatigue Syndrome", Brain, behavior, and immunity, 52: 32-39, doi:10.1016/j.bbi.2015.09.013
- ↑ Loebel, Madlen; Eckey, Maren; Sotzny, Franziska; Hahn, Elisabeth; Bauer, Sandra; Grabowski, Patricia; Zerweck, Johannes; Holenya, Pavlo; Hanitsch, Leif G.; Wittke, Kirsten; Borchmann, Peter; Rüffer, Jens-Ulrich; Hiepe, Falk; Ruprecht, Klemens; Behrends, Uta; Meindl, Carola; Volk, Hans-Dieter; Reimer, Ulf; Scheibenbogen, Carmen (2017), "Serological profiling of the EBV immune response in Chronic Fatigue Syndrome using a peptide microarray", PLOS ONE, 12 (6): e0179124, doi:10.1371/journal.pone.0179124
- ↑ Scheibenbogen, Carmen; Freitag, Helma; Blanco, Julià; Capelli, Enrica; Lacerda, Eliana; Authier, Jerome; Meeus, Mira; Castro Marrero, Jesus; Nora-Krukle, Zaiga; Oltra, Elisa; Strand, Elin Bolle; Shikova, Evelina; Sekulic, Slobodan; Murovska, Modra (July 26, 2017). "The European ME/CFS Biomarker Landscape project: an initiative of the European network EUROMENE". Journal of Translational Medicine. 15 (1). doi:10.1186/s12967-017-1263-z. ISSN 1479-5876. PMC 5530475. PMID 28747192.
- ↑ Sotzny, Franziska; Blanco, Julià; Capelli, Enrica; Castro-Marrero, Jesús; Steiner, Sophie; Murovska, Modra; Scheibenbogen, Carmen (2018), "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome – Evidence for an autoimmune disease", Autoimmunity Reviews, doi:10.1016/j.autrev.2018.01.009
- ↑ Scheibenbogen, Carmen; Loebel, Madlen; Freitag, Helma; Krueger, Anne; Bauer, Sandra; Antelmann, Michaela; Doehner, Wolfram; Scherbakov, Nadja; Heidecke, Harald; Reinke, Petra; Volk, Hans-Dieter; Grabowski, Patricia (2018). "Immunoadsorption to remove ß2 adrenergic receptor antibodies in Chronic Fatigue Syndrome CFS/ME". PLoS ONE. 13 (3): e0193672. doi:10.1371/journal.pone.0193672.
- ↑ Yang, Chin-An; Bauer, Sandra; Ho, Yu-Chen; Sotzny, Franziska; Chang, Jan-Gowth; Scheibenbogen, Carmen (August 17, 2018). "The expression signature of very long non-coding RNA in myalgic encephalomyelitis/chronic fatigue syndrome". Journal of Translational Medicine. 16 (1). doi:10.1186/s12967-018-1600-x. ISSN 1479-5876.
- ↑ Estévez-López, Fernando; Castro-Marrero, Jesus; Wang, Xia; Bakken, Inger Johanne; Ivanovs, Andrejs; Nacul, Luis; Sepúlveda, Nuno; Strand, Elin B.; Pheby, Derek; Alegre, José; Scheibenbogen, Carmen; Shikova, Evelina; Lorusso, Lorenzo; Capelli, Enrica; Sekulic, Slobodan; Lacerda, Eliana; Murovska, Modra (September 1, 2018). "Prevalence and incidence of myalgic encephalomyelitis/chronic fatigue syndrome in Europe—the Euro-epiME study from the European network EUROMENE: a protocol for a systematic review". BMJ Open. 8 (9): e020817. doi:10.1136/bmjopen-2017-020817. ISSN 2044-6055. PMID 30181183.
- ↑ Rasa, Santa; Nora-Krukle, Zaiga; Henning, Nina; Eliassen, Eva; Shikova, Evelina; Harrer, Thomas; Scheibenbogen, Carmen; Murovska, Modra; Prusty, Bhupesh K.; European Network on ME/CFS (EUROMENE) (October 1, 2018). "Chronic viral infections in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)". Journal of Translational Medicine. 16 (1). doi:10.1186/s12967-018-1644-y. ISSN 1479-5876. PMID 30285773.