Central nervous system fatigue

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Central nervous system fatigue, or central fatigue, is a form of fatigue that is associated with changes in the synaptic concentration of neurotransmitters within the central nervous system (CNS), including the brain and spinal cord, which affects exercise performance and muscle function and cannot be explained by peripheral factors that affect muscle function.

Central nervous system fatigue in ME/CFS[edit | edit source]

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References[edit | edit source]

  1. Johnson, Cort (September 3, 2014). "Fatigue Explained? Japanese Assert Brain Damage Causes Fatigue in Chronic Fatigue Syndrome - Health Rising". Health Rising. Retrieved September 27, 2018.