Christopher Armstrong: Difference between revisions

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'''Christopher William Armstrong''', PhD, performs research in the Department of Biochemistry and Molecular Biology and the [[Bio21 Molecular Science and Biotechnology Institute|Bio21 Molecular Science & Biotechnology Institute]] at the University of Melbourne, Melbourne, Australia with an interest in the dysfunction of energy metabolism of people with [[myalgic encephalomyelitis]]/[[chronic fatigue syndrome]] (ME/CFS).  
'''Christopher William Armstrong''', PhD, performs research in the Department of Biochemistry and Molecular Biology and the [[Bio21 Molecular Science and Biotechnology Institute|Bio21 Molecular Science & Biotechnology Institute]] at the University of Melbourne, Melbourne, Australia with an interest in the dysfunction of energy metabolism of people with [[myalgic encephalomyelitis]]/[[chronic fatigue syndrome]] (ME/CFS).  


Dr. Armstrong is a member of the Working Group which offers their expertise and resources to the [[ME/CFS Collaborative Research Center at Stanford University]].
Dr. Armstrong is a member of the Working Group which offers their expertise and resources to the [[ME/CFS Collaborative Research Center at Stanford University]].<ref>{{Cite web|url=https://bos.etapestry.com/prod/viewEmailAsPage.do?erRef=773.0.423082047&databaseId=OMF&mailingId=34274682&jobRef=773.0.506425459&key=b6b9237b3ebd1e462a5d11dbc5c4dae&personaRef=773.0.423082048&memberId=1348639685|title=OMF grants $1.2M to Ramp Up Collaborative Research Center at Stanford University|website=Open Medicine|access-date=2019-07-03}}</ref>  
<ref>{{Cite web|url=https://bos.etapestry.com/prod/viewEmailAsPage.do?erRef=773.0.423082047&databaseId=OMF&mailingId=34274682&jobRef=773.0.506425459&key=b6b9237b3ebd1e462a5d11dbc5c4dae&personaRef=773.0.423082048&memberId=1348639685|title=OMF grants $1.2M to Ramp Up Collaborative Research Center at Stanford University|website=Open Medicine|access-date=2019-07-03}}</ref>  


[[ME Australia]] interviewed Dr Armstrong and wrote a profile on him [https://meaustralia.net/2019/02/20/meet-the-scientists-dr-christopher-armstrong/ 'Meet the Scientists: Dr Christopher Armstrong'].
[[ME Australia]] interviewed Dr Armstrong and wrote a profile on him 'Meet the Scientists: Dr Christopher Armstrong'.<ref>{{Cite web|url=https://meaustralia.net/2019/02/20/meet-the-scientists-dr-christopher-armstrong/|title=Meet the Scientists: Dr Christopher Armstrong|last=Australia|first=~ ME news|date=2019-02-20|website=ME Australia|language=en-US|access-date=2020-02-18}}</ref>


In 2018, Dr Armstrong was part of delegation briefing Australia's Chief Medical Officer, Prof Brendan Murphy, on research into ME.<ref>{{Cite news|url=https://meaustralia.net/2018/04/22/scientists-and-dr-tuller-brief-australias-chief-medical-officer/|title=Scientists and Dr Tuller brief Australia’s Chief Medical Officer|date=2018-04-22|work=ME Australia|access-date=2018-10-02|language=en-US}}</ref>  
In 2018, Dr Armstrong was part of delegation briefing Australia's Chief Medical Officer, Prof Brendan Murphy, on research into ME.<ref>{{Cite news|url=https://meaustralia.net/2018/04/22/scientists-and-dr-tuller-brief-australias-chief-medical-officer/|title=Scientists and Dr Tuller brief Australia’s Chief Medical Officer|date=2018-04-22|work=ME Australia|access-date=2018-10-02|language=en-US}}</ref>  


==Awards==
==Awards==
*2016 Ramsay Award Program grant recipient, sponsored by the [[Solve ME/CFS Initiative]]. This grant, shared with [[Geraldine Cambridge]], University College London, and [[Fane Mensah]], University College London, will focus on the [http://solvecfs.org/metabolic-analysis-of-b-cell-maturation-in-myalgic-encephalomyelitischronic-fatigue-syndrome/ metabolic analysis of B-Cell maturation in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome]<ref>{{cite web |url=http://solvecfs.org/2016-ramsay-award-program-results/|title=2016 Ramsay Award Program Results |last= |first= |date= |website=Solve ME/CFS |publisher= |access-date=2019-07-03 |quote=}}</ref>
*2016 [[Ramsay Award]] Program grant recipient, sponsored by the [[Solve ME/CFS Initiative]]. This grant, shared with [[Geraldine Cambridge]], University College London, and [[Fane Mensah]], University College London, will focus on the metabolic analysis of B-Cell maturation in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome<ref>{{cite web |url=http://solvecfs.org/2016-ramsay-award-program-results/|title=2016 Ramsay Award Program Results |last= |first= |date= |website=Solve ME/CFS |publisher= |access-date=2019-07-03 |quote=}}</ref><ref>{{Cite web|url=https://solvecfs.org/metabolic-analysis-of-b-cell-maturation-in-myalgic-encephalomyelitischronic-fatigue-syndrome/|title=Metabolic Analysis of B-Cell Maturation in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome|date=2016-12-07|website=Solve ME/CFS Initiative|language=en-US|access-date=2020-02-18}}</ref>


==Books==
==Books==
*2014, [http://www.academia.edu/11578244/CHAPTER_FIVE_Metabolism_in_Chronic_Fatigue_Syndrome Chapter Five in ''Advances in Clinical Chemistry, Vol. 66,'' published by Elsevier; "Metabolism in Chronic Fatigue Syndrome," by Christopher W. Armstrong,] [[Neil McGregor | Neil R. McGregor]], [[Henry Butt|Henry L. Butt]], and [[Paul Gooley |Paul R. Gooley]]<ref>{{Cite journal|last=Armstrong|first=Christopher W.|last2=McGregor|first2=Neil R.|last3=Butt|first3=Henry L.|last4=Gooley|first4=Paul R.|date=2014|title=Metabolism in Chronic Fatigue Syndrome|url=http://dx.doi.org/10.1016/b978-0-12-801401-1.00005-0|publisher=Elsevier|pages=121–172|isbn=9780128014011}}</ref>  
*2014, Chapter Five in ''Advances in Clinical Chemistry, Vol. 66,'' published by Elsevier; "Metabolism in Chronic Fatigue Syndrome," by Christopher W. Armstrong, [[Neil McGregor | Neil R. McGregor]], [[Henry Butt|Henry L. Butt]], and [[Paul Gooley |Paul R. Gooley]]<ref>{{Cite journal|last=Armstrong|first=Christopher W.|last2=McGregor|first2=Neil R.|last3=Butt|first3=Henry L.|last4=Gooley|first4=Paul R.|date=2014|title=Metabolism in Chronic Fatigue Syndrome|url=http://dx.doi.org/10.1016/b978-0-12-801401-1.00005-0|publisher=Elsevier|pages=121–172|isbn=9780128014011}}</ref> ([http://www.academia.edu/11578244/CHAPTER_FIVE_Metabolism_in_Chronic_Fatigue_Syndrome Link])
 
 
==Notable studies==
==Notable studies==
*2012, NMR metabolic profiling of serum identifies amino acid disturbances in chronic fatigue syndrome<ref>{{Cite journal|last=Armstrong|first=Christopher W.|authorlink=Christopher Armstrong|last2=McGregor|first2=Neil R.|authorlink2=Neil McGregor|last3=Sheedy|first3=John R.|authorlink3=|last4= Buttfield|first4=Ianauthorlink4=|last5=Butt|first5=Henry L.|authorlink5=Henry Butt|last6=Gooley|first6=Paul R.|authorlink6=Paul Gooley|title=NMR metabolic profiling of serum identifies amino acid disturbances in chronic fatigue syndrome|journal= Clinica Chimica Acta|volume=413|issue=19–20|page=1525–1531|date=2012|doi=10.1016/j.cca.2012.06.022}}</ref> - [https://www.ncbi.nlm.nih.gov/pubmed/22728138 (Abstract)]
*2012, NMR metabolic profiling of serum identifies amino acid disturbances in chronic fatigue syndrome<ref>{{Cite journal|last=Armstrong|first=Christopher W.|authorlink=Christopher Armstrong|last2=McGregor|first2=Neil R.|authorlink2=Neil McGregor|last3=Sheedy|first3=John R.|authorlink3=|last4= Buttfield|first4=Ianauthorlink4=|last5=Butt|first5=Henry L.|authorlink5=Henry Butt|last6=Gooley|first6=Paul R.|authorlink6=Paul Gooley|title=NMR metabolic profiling of serum identifies amino acid disturbances in chronic fatigue syndrome|journal= Clinica Chimica Acta|volume=413|issue=19–20|page=1525–1531|date=2012|doi=10.1016/j.cca.2012.06.022}}</ref> - [https://www.ncbi.nlm.nih.gov/pubmed/22728138 (Abstract)]
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==References==
==References==
<references>
<references>
<ref name="Armstrong, 2017">{{Citation
<ref name="Armstrong, 2017">{{Citation
| last1  = Armstrong        | first1 = Christopher W.    | authorlink1 = Christopher Armstrong
| last1  = Armstrong        | first1 = Christopher W.    | authorlink1 = Christopher Armstrong

Revision as of 21:29, February 18, 2020

Source:SMCI

Christopher William Armstrong, PhD, performs research in the Department of Biochemistry and Molecular Biology and the Bio21 Molecular Science & Biotechnology Institute at the University of Melbourne, Melbourne, Australia with an interest in the dysfunction of energy metabolism of people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).

Dr. Armstrong is a member of the Working Group which offers their expertise and resources to the ME/CFS Collaborative Research Center at Stanford University.[1]

ME Australia interviewed Dr Armstrong and wrote a profile on him 'Meet the Scientists: Dr Christopher Armstrong'.[2]

In 2018, Dr Armstrong was part of delegation briefing Australia's Chief Medical Officer, Prof Brendan Murphy, on research into ME.[3]

Awards[edit | edit source]

Books[edit | edit source]

Notable studies[edit | edit source]

  • 2012, NMR metabolic profiling of serum identifies amino acid disturbances in chronic fatigue syndrome[7] - (Abstract)
  • 2014, Metabolism in chronic fatigue syndrome[8] - (Abstract)
  • 2015, Metabolic profiling reveals anomalous energy metabolism and oxidative stress pathways in chronic fatigue syndrome patients[9] - (Abstract)
  • 2016, Widespread pain and altered renal function in ME/CFS patients[10] - (Abstract)
  • 2017, The association of fecal microbiota and fecal, blood serum and urine metabolites in myalgic encephalomyelitis/chronic fatigue syndrome[11] - (Abstract)
  • 2018, CD24 Expression and B Cell Maturation Shows a Novel Link With Energy Metabolism: Potential Implications for Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome[12] - (Full Text)
  • 2019, Post-Exertional Malaise Is Associated with Hypermetabolism, Hypoacetylation and Purine Metabolism Deregulation in ME/CFS Cases[13] - (Full text)

Talks and interviews[edit | edit source]

Online presence[edit | edit source]

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. ↑ "OMF grants $1.2M to Ramp Up Collaborative Research Center at Stanford University". Open Medicine. Retrieved July 3, 2019.
  2. ↑ Australia, ~ ME news (February 20, 2019). "Meet the Scientists: Dr Christopher Armstrong". ME Australia. Retrieved February 18, 2020.
  3. ↑ "Scientists and Dr Tuller brief Australia's Chief Medical Officer". ME Australia. April 22, 2018. Retrieved October 2, 2018.
  4. ↑ "2016 Ramsay Award Program Results". Solve ME/CFS. Retrieved July 3, 2019.
  5. ↑ "Metabolic Analysis of B-Cell Maturation in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome". Solve ME/CFS Initiative. December 7, 2016. Retrieved February 18, 2020.
  6. ↑ Armstrong, Christopher W.; McGregor, Neil R.; Butt, Henry L.; Gooley, Paul R. (2014). "Metabolism in Chronic Fatigue Syndrome". Elsevier: 121–172. ISBN 9780128014011. Cite journal requires |journal= (help)
  7. ↑ Armstrong, Christopher W.; McGregor, Neil R.; Sheedy, John R.; Buttfield, Ianauthorlink4=; Butt, Henry L.; Gooley, Paul R. (2012). "NMR metabolic profiling of serum identifies amino acid disturbances in chronic fatigue syndrome". Clinica Chimica Acta. 413 (19–20): 1525–1531. doi:10.1016/j.cca.2012.06.022.
  8. ↑ Armstrong, Christopher W.; McGregor, Neil R.; Butt, Henry L.; Gooley, Paul R. (2014). "Metabolism in chronic fatigue syndrome". Advances in Clinical Chemistry. 66: 121–172. ISSN 0065-2423. PMID 25344988.
  9. ↑ Armstrong, Christopher W.; McGregor, Neil R.; Lewis, Donald P.; Butt, Henry L.; Gooley, Paul R. (2015). "Metabolic profiling reveals anomalous energy metabolism and oxidative stress pathways in chronic fatigue syndrome patients". Metabolomics. 11 (6): 1626–1639. doi:10.1007/s11306-015-0816-5.
  10. ↑ McGregor, Neil R.; Armstrong, Christopher W.; Lewis, Donald P.; Butt, Henry L.; Gooley, Paul R. (July 2016). "Metabolic profiling reveals anomalous energy metabolism and oxidative stress pathways in chronic fatigue syndrome patients". Fatigue: Biomedicine, Health & Behavior. 4 (3): 132–145. doi:10.1080/21641846.2016.1207400.
  11. ↑ Armstrong, Christopher W.; McGregor, Neil R.; Lewis, Donald P.; Butt, Henry L.; Gooley, Paul R. (2017), "The association of fecal microbiota and fecal, blood serum and urine metabolites in myalgic encephalomyelitis/chronic fatigue syndrome", Metabolomics, 13 (1), doi:10.1007/s11306-016-1145-z
  12. ↑ Mensah, Fane F. K.; Armstrong, Christopher W.; Reddy, Venkat; Bansal, Amolak S.; Berkovitz, Saul; Leandro, Maria J.; Cambridge, Geraldine (2018). "CD24 Expression and B Cell Maturation Shows a Novel Link With Energy Metabolism: Potential Implications for Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome". Frontiers in Immunology. 9. doi:10.3389/fimmu.2018.02421. ISSN 1664-3224.
  13. ↑ McGregor, Neil R.; Armstrong, Christopher W.; Lewis, Donald P.; Gooley, Paul R. (July 4, 2019). "Post-Exertional Malaise Is Associated with Hypermetabolism, Hypoacetylation and Purine Metabolism Deregulation in ME/CFS Cases". Diagnostics. 9 (3): 70. doi:10.3390/diagnostics9030070. ISSN 2075-4418.
  14. ↑ "ME/CFS Canadian Collaborative Team Conference program" (PDF). Retrieved March 6, 2019. Cite has empty unknown parameter: |dead-url= (help)

myalgic encephalomyelitis (M.E.) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.

serum The clear yellowish fluid that remains from blood plasma after clotting factors have been removed by clot formation. (Blood plasma is simply blood that has had its blood cells removed.)

renal involving, related to or in the area of the kidneys

microbiome The full collection of microscopic organisms (especially bacteria and fungi) which are present in a particular environment, particularly inside the human body.

serum The clear yellowish fluid that remains from blood plasma after clotting factors have been removed by clot formation. (Blood plasma is simply blood that has had its blood cells removed.)

metabolite A chemical compound produced by, or involved in, metabolism. The term is often used to refer to the degradation products of drugs in the body.

metabolomics The analysis of the chemical metabolism within cells, tissues or organisms. The term is often used to refer to the full set of metabolites found in a cell in a given environment.

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