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Cytomegalovirus
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{{Cleanup/Citations_needed | date = 2022}} '''Cytomegalovirus''' (CMV) is a common [[herpesvirus]] found in humans. Like other herpesviruses, it is a life-long infection that remains in a latent state inside the human body, until it is 'reactivated' by appropriate conditions. ==Prevalence == CMV infects between 60% to 70% of adults in industrialized countries and close to 100% in emerging countries.{{citation needed | date = 2022}} Much is unknown about CMV, although it has been found in salivary glands and myeloid blood cells such as [[monocyte]]s. It has also been linked to the development of certain cancers. Congenital CMV is a leading infectious cause of deafness, learning disabilities, and intellectual disability. A common treatment for CMV is [[valganciclovir]], commonly known as Valcyte.<ref name="Gupta2019">{{Cite book | last = Gupta | first = Mohit | last2 = Shorman | first2 = Mahmoud | date = 2019 | title=Cytomegalovirus |url =http://www.ncbi.nlm.nih.gov/books/NBK459185/|location=Treasure Island (FL)| publisher = StatPearls Publishing|pmid=29083720}}</ref> Several herpesviruses including cytomegalovirus may cause false positives on [[Lyme disease]] tests.<ref name="Goossens1999a">{{Cite journal | title = Epstein-barr virus and cytomegalovirus infections cause false-positive results in IgM two-test protocol for early lyme borreliosis | date = 1999-05-01 | url = https://doi.org/10.1007/BF02561539|journal=Infection|volume=27|issue=3 | pages = 231–231 | last = Goossens | first = H.A.T. | last2 = van den Bogaard | first2 = A. E. J.M. | last3 = Nohlmans | first3 = M. K.E. | last4 = van den Bogaard | first4 = A. E. J.M. | language=en|doi=10.1007/BF02561539|issn=1439-0973}}</ref><ref name="Goossens1999b">{{Cite journal | title = Evaluation of Fifteen Commercially Available Serological Tests for Diagnosis of Lyme Borreliosis | date = 1999-09-01 | url = https://doi.org/10.1007/s100960050347|journal=European Journal of Clinical Microbiology and Infectious Diseases|volume=18|issue=8 | pages = 551–560 | last = Goossens | first = H.A.T. | last2 = van den Bogaard | first2 = A.E. | last3 = Nohlmans | first3 = M. K. E.|language=en|doi=10.1007/s100960050347|issn=1435-4373}}</ref><ref name="Dessau2018">{{Cite journal | title = To test or not to test? Laboratory support for the diagnosis of Lyme borreliosis: a position paper of ESGBOR, the ESCMID study group for Lyme borreliosis | date = 2018-02-01 | url = https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(17)30488-3/abstract|journal=Clinical Microbiology and Infection|volume=24|issue=2 | pages = 118–124 | last = Dessau|first = R.B. | last2 = Dam | first2 = A. P. van | last3 = Fingerle | first3 = V. | last4 = Gray | first4 = J. | last5 = Hovius | first5 = J.W. | last6 = Hunfeld | first6 = K.P. | last7 = Jaulhac | first7 = B. | last8 = Kahl | first8 = O. | last9 = Kristoferitsch | first9 = W. | last10 = Lindgren | first10 = P.-E. | last11 = Markowicz | first11 = M.|language=English|doi=10.1016/j.cmi.2017.08.025|pmid=28887186|issn=1198-743X}}</ref> ==Treatments == *[[Artesunate]] *[[Gancyclovir]] (brand names include Cytovene) *[[Valganciclovir]] (brand names include Valcyte) ==Notable studies== *2020, Cytomegalovirus, Epstein-Barr Virus, and Human herpesvirus-6 Infections in Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome<ref name="Shikova2020">{{Cite journal | last = Shikova | first = Evelina | authorlink = | last2 = Reshkova | first2 = Valentina | authorlink2 = | last3 = Kumanova | first3 = Аntoniya | author-link3 = | last4 = Raleva | first4 = Sevdalina | author-link4 = | last5 = Alexandrova | first5 = Dora | author-link5 = | last6 = Capo | first6 = Natasa | author-link6 = | last7 = Murovska | first7 = Modra | date = 2020 | title=Cytomegalovirus, Epstein-Barr virus, and human herpesvirus-6 infections in patients with myalgic еncephalomyelitis/chronic fatigue syndrome | url =https://onlinelibrary.wiley.com/doi/abs/10.1002/jmv.25744|journal=Journal of Medical Virology|language=en|volume=|issue=| pages=|doi=10.1002/jmv.25744|issn=1096-9071|pmc=|pmid=|access-date=|quote=|via=}}</ref> - [https://doi.org/10.1002/jmv.25744 (Abstract)] == See also == * [[List of herpesvirus infection studies]] * [[Abortive infection theory of ME/CFS]] (Dr Lerner's theory that abortive herpesviruses cause ME/CFS) == Learn more == ==References== {{Reflist}} [[Category:Infectious agents]] [[Category:Triggers and risk factors]] [[Category:Virology]] [[Category:Viruses]] [[Category:Herpesviruses]]
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