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D-lactic acid
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'''D-lactic acid''' (sometimes referred to by the conjugate base D-lactate) is a form of lactic acid produced by bacteria such as ''[[Enterococcus]]'' and ''[[Streptococcus]]''. It is an indicator of bacterial overgrowth in the [[gastrointestinal system|gastrointestinal tract]]. It's produced by bacteria in the colon when carbohydrates are not completely absorbed in the [[small intestine]], such as in the case of patients who have had surgical resection of the bowel. In large quantities it can lead to [[Lactic acidosis|d-lactic acidosis]]. D-lactic acid is different from [[Lactic acid|L-lactic acid]] in that it cannot be metabolized by humans and must be excreted through the [[kidney]]s. It can produce a variety of neurological symptoms including [[dysarthria]] and [[ataxia]] and is elevated in [[chronic fatigue syndrome]].<ref>{{Cite journal | last = Sheedy|first = John R. | authorlink = John Sheedy | last2 = Wettenhall | first2 = Richard E.H. | authorlink2 = Richard Wettenhall | last3 = Scanlon | first3 = Denis | author-link3 = Denis Scanlon | last4 = Gooley | first4 = Paul R. | author-link4 = Paul Gooley | last5 = Lewis | first5 = Donald P. | author-link5 = Donald Lewis | last6 = McGregor | first6 = Neil | last7 = Stapleton | first7 = David I. | last8 = Butt | first8 = Henry L. | last9 = DE Meirleir | first9 = Kenny L. | date = Jul 2009 | title = Increased d-lactic Acid intestinal bacteria in patients with chronic fatigue syndrome | url =https://www.ncbi.nlm.nih.gov/pubmed/19567398|journal=In Vivo (Athens, Greece)|volume=23|issue=4 | pages = 621β628|issn=0258-851X|pmid=19567398|quote=|via=}}</ref> ==Learn more== *2016, [http://www.cortjohnson.org/blog/2016/03/01/lactate-fibromyalgia-chronic-fatigue-syndrome/ Lactate β Is it Everywhere in Fibromyalgia and Chronic Fatigue Syndrome (ME/CFS)?] *2016, [http://www.healthrising.org/blog/2016/04/11/migraine-me-cfs-fibromyalgia-oxygen-lactate-triad/ Migraine, ME/CFS and Fibromyalgia β Low Oxygen, High Lactate Disorders?] == See also == *[[Lactic acid]] *[[Small intestinal bacterial overgrowth]] *[[Dysbiosis]] *[[Lactic acidosis]] ==References== {{Reflist}} [[Category:Biochemistry and cell biology]]
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