Dauer

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Revision as of 04:13, November 8, 2016 by DxCFS (talk | contribs) (Letter: Reply to VOGT Et Al.)

Dauer is the German word for persistence or long-lived.[1][2]

Dauer larva[edit | edit source]

Wikipedia uses the words "endurance", "duration" or "permanent" and describes an alternative developmental stage of nematode worms, particularly Caenorhabditis elegans, whereby the larva goes into a type of stasis and can survive harsh conditions.[3]

Used in relation to Chronic Fatigue Syndrome[edit | edit source]

Dauer, or hibernation, was used to explain Chronic Fatigue Syndrome in the paper Metabolic features of chronic fatigue syndrome.[4]

Letter: Reply to VOGT Et Al.[edit | edit source]

"... chemical details of the metabolic findings in ME/CFS led directly to a survey of other hypometabolic syndromes like dauer, diapause, torpor, hibernation, and caloric restriction. It was the detailed nature and specific pattern of abnormalities affecting six pathways (sphingolipids, phospholipids, purines, cholesterol, polyamines, and redox metabo-lism), and not the over 50 other biochemical pathways interrogated, that focused our attention on dauer. In dauer, there is a reprioritization of sensory processing that is metabolically controlled (9). This situation bears similarities to ME/CFS.[5]

References[edit | edit source]