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Diagnostic biomarker
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===CellTrend diagnostic test=== CellTrend bases its test on the theory that a subset of 20-30% of all patients suffering from ME/CFS have developed elevated levels of three [[autoantibody|auto-antibodies]], i.e., auto-antibodies against the b2-adrenergic receptor, auto-antibodies against the [[muscarinic cholinergic receptor|muscarinic cholinergic receptor 3]] (M3) and auto-antibodies against the [[muscarinic cholinergic receptor 4]] (M4).<ref>{{Cite web | url = https://www.celltrend.de/en/pots-cfs-me-crps.html | title = POTS - CFS/ME - CRPS|website=CellTrend Luckenwalde|language=en-US|access-date=2020-02-04}}</ref><ref name="Loebel, 2016" /> Obstacle for use: Only detects a subset 20-30%. Not widely accepted. Patients pay the test cost.
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