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Eicosapentaenoic acid
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==Nervous system== EPA is found in very low levels in the brain (in contrast to DHA, which is the primary structural Omega 3 in the brain and found in abundance). However, EPA still has important [[nervous system|neurological]] and psychiatric effects. EPA inhibits [[Phospholipase A2]] (PLA2), an enzyme that breaks down [[Phospholipid|phospholipids]], the major component of cell membranes. Increased PLA2 activity has been observed in the [[cerebrospinal fluid]] of patients with [[Alzheimer's]]<ref name="chalbot2011" /> and [[multiple sclerosis]]. Some animal studies have found that [[fish oil]] increases [[dopamine]], which may be low in CFS patients.<ref name="fishoilrats1998" /><ref name="newbornratbrain2001" /><ref name="striataldopamine2011" />
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