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Empty sella syndrome
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In '''empty sella syndrome''' (ESS), the [[pituitary gland]] shrinks or becomes flattened, filling the [[sella turcica]] with [[cerebrospinal fluid]] on [[Neuroimaging|imaging]] instead of the normal pituitary. The reported prevalence of primary empty sella in general population is 8–35 %, with a higher incidence in females, the ratio being 5:1.<ref>{{Cite journal | last = Aruna | first = P | date = April 2014 | title = Partial Empty Sella Syndrome: A Case Report and Review | url =https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990803/|journal=Indian Journal of Biochemistry|volume=| pages=|via=}}</ref> It is generally found in middle aged women who are obese and hypertensive. It is unknown whether this is causal or a consequence of hormonal abnormalities arising from pituitary changes. However, most people with ESS are asymptomatic.<ref>{{Cite web | url = https://rarediseases.org/rare-diseases/empty-sella-syndrome/ | title = Empty Sella Syndrome | last = | first = | date = |website=National Organization for Rare Disorders|archive-url=|archive-date=|url-status=|access-date=}}</ref> A finding of ESS on an [[MRI]] may be an indication of [[intracranial hypertension]], particular if symptoms of intracranial pressure are present.<ref>{{Cite journal | last = Saindane1 | first = Amit | date = May 2013 | title = Factors Determining the Clinical Significance of an “Empty” Sella Turcica| url = https://www.ajronline.org/doi/abs/10.2214/AJR.12.9013|journal=American Journal of Roentgenology|volume=| pages=|via=}}</ref> == References == {{Reflist}} [[Category:Diagnoses]] [[Category:Potential comorbidities]] [[Category:Endocrine system]]
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