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Epidemic myalgic encephalomyelitis
(section)
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== Onset == The incubation period was generally estimated at 4 to 8 days.<ref name="Sigurdsson1950" /><ref name="Parish1978" /><ref name="Sigurdsson1956">{{Cite journal| url = https://www.ncbi.nlm.nih.gov/pubmed/13320872 | title = The Lancet | last = Sigurdsson | first = B | author-link = Bjรถrn Sigurdsson | date = May 1956|journal=Clinical findings six years after outbreak of Akureyri disease|volume=270 | pages = 766-7|via=}}</ref> The illness generally began with a prodromal period of [[Flu-like illness|flu-like symptoms]], symptoms of an upper respiratory tract infection, [[low-grade fever]], [[sore throat]] or [[Gastrointestinal system|gastrointestinal]] distress,<ref name="Pellew1951" /><ref name="Ramsay1978" /><ref name="Levine1997">{{Cite journal | last = Levine | first = P. H. | author-link = Paul Levine | last2 = Snow | first2 = P. G. | authorlink2 = | last3 = Ranum | first3 = B. A. | authorlink3 = | last4 = Paul | first4 = C. | authorlink4 = | last5 = Holmes | first5 = M. J. | authorlink5 = | date = 1997-04-14 | title = Epidemic neuromyasthenia and chronic fatigue syndrome in west Otago, New Zealand. A 10-year follow-up | url =https://www.ncbi.nlm.nih.gov/pubmed/9125006|journal=Archives of Internal Medicine|volume=157|issue=7 | pages = 750โ754|issn=0003-9926|pmid=9125006|quote=|via=}}</ref> followed by a symptom complex involving [[muscle weakness]], [[muscle fatigability]] and [[central nervous system]] involvement in a significant proportion of cases.<ref name="Parish1978" /><ref name="Shelokov, 1957" />
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