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Epstein-Barr virus
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== Initial infection == [[File:Epstein-barr virus (ebv).jpg|thumb|A stained sample of Epstein-Barr virus.]] Symptoms of EBV infection include: * [[fatigue]] * [[fever]] * [[rash]] * inflamed [[sore throat|throat]] * [[swollen lymph nodes]] * enlarged [[spleen]] * swollen [[liver]]<ref name="CDC">{{Cite web | url=http://www.cdc.gov/epstein-barr/about-ebv.html | title = Epstein-barr {{!}} Mononucleosis {{!}} About Virus {{!}} Mono | date = 2018-05-10 | website = [[Centers for Disease Control and Prevention]]|language=en-us|access-date=2018-11-14}}</ref> ===Age of infection=== Most people acquire EBV before the age of ten. Typically, young children who acquire EBV are either not symptomatic or have mild symptoms that are hard to distinguish from a cold or other other mild, childhood illnesses.<ref>{{Cite book|title=Fields Virology|chapter=Epstein-Barr virus|date=2001|publisher=Lippincott Williams & Wilkins|location=Philadelphia, PA|pages=2575β2627|editor-last=Knipe|editor-first=DM|editor-last2=Howley|editor-first2=PM|last=Rickinson|first=AB|last2=Kieff|first2=E}}</ref> In adolescents and young adults, EBV can cause [[infectious mononucleosis]] (IM), also known as glandular fever.<ref name="CDC" /> IM is characterized by [[fever]], [[sore throat]], [[swollen lymph nodes]], [[pain|body aches]], and [[fatigue]]. It generally resolves with rest and only rarely causes serious complications. It typically occurs in people who have not been exposed to EBV in early childhood, and in comparison, is more severe than infection in childhood (i.e., it can last for months). Following initial infection, EBV can reactivate and has been shown to have many connections with various chronic illnesses. Relative to initial infections, reactivated EBV is much more severe.
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