GETSET trial: Difference between revisions
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The '''GETSET''' trial (short for ''Graded Exercise Therapy Guided Self-Help Trial for Patients with Chronic Fatigue Syndrome'') was a trial investigating the effectiveness of "guided graded exercise self-help" in patients with [[CFS/ME]]. The protocol was published in June 2016.<ref name="getsetprotocol" /> The results were published in June 2017.<ref name="getset" /> | The '''GETSET''' trial (short for ''Graded Exercise Therapy Guided Self-Help Trial for Patients with Chronic Fatigue Syndrome'') was a trial investigating the effectiveness of "guided graded exercise self-help" in patients with [[CFS/ME]]. The protocol was published in June 2016.<ref name="getsetprotocol" /> The results were published in June 2017.<ref name="getset" /> | ||
==Researchers== | |||
Lead Author [[Lucy Clark]], [[Peter White]], Francesca Pesola, Janice M Thomas, Mario Vergara-Williamson and Michelle Beynon | |||
==Funding== | ==Funding== | ||
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==Publication== | ==Publication== | ||
The results were published on 22 June 2017 in the [[The Lancet|Lancet]] [http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2816%2932589-2/fulltext 'Guided graded exercise self-help plus specialist medical care versus specialist medical care alone for chronic fatigue syndrome (GETSET): a pragmatic randomised controlled trial'] <ref>[[QMUL]] Press release: [http://www.qmul.ac.uk/media/news/items/smd/198480.html# Guided self-help approach to graded exercise programme is safe and may reduce fatigue for patients with chronic fatigue syndrome] </ref> . | The results were published on 22 June 2017 in the [[The Lancet|Lancet]] [http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2816%2932589-2/fulltext 'Guided graded exercise self-help plus specialist medical care versus specialist medical care alone for chronic fatigue syndrome (GETSET): a pragmatic randomised controlled trial'] <ref>[[QMUL]] Press release: [http://www.qmul.ac.uk/media/news/items/smd/198480.html# Guided self-help approach to graded exercise programme is safe and may reduce fatigue for patients with chronic fatigue syndrome] </ref> . | ||
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It was reported in the Telegraph as [http://www.telegraph.co.uk/science/2017/06/22/exercise-can-help-chronic-fatigue-syndrome-study-shows/ Exercise can help chronic fatigue syndrome, study shows] | It was reported in the Telegraph as [http://www.telegraph.co.uk/science/2017/06/22/exercise-can-help-chronic-fatigue-syndrome-study-shows/ Exercise can help chronic fatigue syndrome, study shows] | ||
and other media outlets [http://www.emergency-live.com/en/news/defeating-chronic-fatigue-thanks-to-guided-self-help-approach-to-exercise/ Defeating chronic fatigue thanks to guided self-help approach to exercise]. | and other media outlets [http://www.emergency-live.com/en/news/defeating-chronic-fatigue-thanks-to-guided-self-help-approach-to-exercise/ Defeating chronic fatigue thanks to guided self-help approach to exercise]. | ||
==Criticism== | ==Criticism== | ||
Dr [[David Tuller]] has criticised the trial [http://www.virology.ws/2017/06/28/trial-by-error-continued-more-on-graded-exercise-from-peter-white-and-the-lancet/ Trial by Error, Continued: More on Graded Exercise from Peter White and The Lancet]. | Dr [[David Tuller]] has criticised the trial [http://www.virology.ws/2017/06/28/trial-by-error-continued-more-on-graded-exercise-from-peter-white-and-the-lancet/ Trial by Error, Continued: More on Graded Exercise from Peter White and The Lancet]. | ||
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==Documents== | ==Documents== | ||
* [https://www.qmul.ac.uk/wolfson/media/wolfson/current-projects/getset/GET%20guide%20booklet%20version%201%2022062010.pdf Graded Exercise Therapy - A self-help guide for those with chronic fatigue syndrome/myalgic encephalomyelitis] | * [https://www.qmul.ac.uk/wolfson/media/wolfson/current-projects/getset/GET%20guide%20booklet%20version%201%2022062010.pdf Graded Exercise Therapy - A self-help guide for those with chronic fatigue syndrome/myalgic encephalomyelitis] | ||
==See also== | ==See also== | ||
*[[PACE trial]] | |||
[[PACE trial]] | |||
==References== | ==References== | ||
Revision as of 04:09, January 25, 2020
The GETSET trial (short for Graded Exercise Therapy Guided Self-Help Trial for Patients with Chronic Fatigue Syndrome) was a trial investigating the effectiveness of "guided graded exercise self-help" in patients with CFS/ME. The protocol was published in June 2016.[1] The results were published in June 2017.[2]
Researchers[edit | edit source]
Lead Author Lucy Clark, Peter White, Francesca Pesola, Janice M Thomas, Mario Vergara-Williamson and Michelle Beynon
Funding[edit | edit source]
The trial was funded in full by the National Institute for Health Research's Research for Patient Benefit programme.[3]
Protocol[edit | edit source]
The protocol of the trial was published in JMIR Research Protocols in June 2016.[1]
Publication[edit | edit source]
The results were published on 22 June 2017 in the Lancet 'Guided graded exercise self-help plus specialist medical care versus specialist medical care alone for chronic fatigue syndrome (GETSET): a pragmatic randomised controlled trial' [4] .
Commentary was provided by Daniel Claw in the Lancet Guided graded exercise self-help as a treatment of fatigue in chronic fatigue syndrome.
The Science Media Centre provided Expert reaction to study on guided self-help graded exercise therapy as a treatment for chronic fatigue syndrome (CFS).
It was reported in the Telegraph as Exercise can help chronic fatigue syndrome, study shows and other media outlets Defeating chronic fatigue thanks to guided self-help approach to exercise.
Criticism[edit | edit source]
Dr David Tuller has criticised the trial Trial by Error, Continued: More on Graded Exercise from Peter White and The Lancet.
Spoonseekerdotcom has criticised the GETSET trial.[5][6] [7]
Professor Jonathan Edwards criticised the study for its "incompetent level of science".[8]
The ME Association has also criticised the trial ME Association Review: GETSET fails to demonstrate GET can significantly improve physical function.
Additional criticism has been published by other patients [9] [10].
Documents[edit | edit source]
See also[edit | edit source]
References[edit | edit source]
- ↑ 1.0 1.1 Clark, Lucy V.; McCrone, Paul; Ridge, Damien; Cheshire, Anna; Vergara-Williamson, Mario; Pesola, Francesca; White, Peter D. (June 8, 2016), "Graded Exercise Therapy Guided Self-Help Trial for Patients with Chronic Fatigue Syndrome (GETSET): Protocol for a Randomized Controlled Trial and Interview Study", JMIR research protocols, 5 (2): 70, doi:10.2196/resprot.5395, PMC 4917732, PMID 27278762
- ↑ Clark, Lucy V.; Pesola, Francesca; Thomas, Janice; Vergara-Williamson, Mario; Beynon, Michelle; White, Peter D. (June 22, 2017), "Guided graded exercise self-help plus specialist medical care versus specialist medical care alone for chronic fatigue syndrome (GETSET): a pragmatic randomised controlled trial", The Lancet, doi:10.1016/S0140-6736(16)32589-2
- ↑ ISRCTN Registry - GETSET trial (ISRCTN22975026)
- ↑ QMUL Press release: Guided self-help approach to graded exercise programme is safe and may reduce fatigue for patients with chronic fatigue syndrome
- ↑ 23 May 2016, Spoonseekerdotcom - A Few Notes on GETSET
- ↑ 29 June 2017, Do GET Yourself
- ↑ Spotlight on GETSET Julie
- ↑ Phoenix Rising Forum - Trial by Error, Continued: More on Graded Exercise from Peter White and The Lancet
- ↑ https://corsius.wordpress.com/2017/06/23/yet-another-publication-with-misleading-conclusions-from-pace-land/amp/
- ↑ https://www.healthrising.org/blog/2017/06/25/graded-exercise-get-chronic-fatigue-syndrome-underwhelms/
