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Gene expression
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[[File:MEupregulatedgenes.png|alt=Upregulated genes in ME/CFS in one study|thumb|Author: Sweetman et al. Current Research Provides Insight into the Biological Basis and Diagnostic Potential for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Diagnostics 2019 9(3) 73. License: CC-BY-4.0]] The [[National Center for Biotechnology Information]] at the US [[National Institutes of Health]] (NIH) defines '''gene expression''' as "the phenotypic manifestation of a gene or genes by the processes of genetic transcription and genetic translation."<ref name=":0">{{Cite web | url=https://www.ncbi.nlm.nih.gov/probe/docs/applexpression/ | title = Gene Expression | website = ncbi.nlm.nih.gov|access-date=2019-01-31}}</ref> Gene expression takes place in two stages. The first is transcription: the base sequence on [[DNA]] is copied to a molecule of [[Messenger RNA|mRNA]]. Next, translation: the mRNA molecule leaves the cell nucleus for the [[cytoplasm]] and specifies the particular amino acids that will make up individual proteins in the process of [[protein synthesis]].<ref name=":0" /> Gene expression analysis examines patterns of gene expression in transcription, whether under specific conditions or in certain kinds of cells.<ref name=":0" /> ==Notable studies == * 2009, A gene signature for post-infectious chronic fatigue syndrome<ref>{{Cite journal | title = A gene signature for post-infectious chronic fatigue syndrome | url =https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716361/|journal=BMC Medical Genomics | date = 2009-06-25|issn=1755-8794|pmc=2716361|pmid=19555476 | pages = 38|volume=2|doi=10.1186/1755-8794-2-38 | first = John W | last = Gow | first2 = Suzanne | last2 = Hagan | first3 = Pawel | last3 = Herzyk | first4 = Celia | last4 = Cannon | first5 = Peter O | last5 = Behan | first6 = Abhijit | last6 = Chaudhuri|issue=|quote= | author-link = John Gow | authorlink2 = Suzanne Hagan | authorlink3 = Pawel Herzyk | authorlink4 = Celia Cannon | authorlink5 = Peter Behan|via= | authorlink6 = Abhijit Chaudhuri}}</ref> ==Learn more== *[https://en.wikipedia.org/wiki/Gene_expression Wikipedia - Gene expression] ==See also== *[[:Category:Genes|Genes (category)]] ==References == {{Reflist}}{{stub}} [[Category:Biochemistry and cell biology]] [[Category:Genes]]
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