Glutamine

Glutamine, also known as L-glutamine, is the most abundant free amino acid circulating in the blood as well as stored in the skeletal muscles. Since it can be made by the human body, it is considered a "non-essential" amino acid. Glutamine is a diverse amino acid that is utilized in numerous vital functions. It is necessary for rapidly dividing cells, including those of the gut and immune system. Glutamine is sometimes used by the mitochondria in energy production and is a precursor to the neurotransmitter, glutamate. Glutamate is perhaps best known as the most common excitatory neurotransmitter, and under normal conditions it plays an important role in learning and memory.

Patients who are concerned about increased intestinal permeability (AKA leaky gut) often supplement with L-glutamine as it is thought to help repair the intestinal tract. Leaky gut is thought by these patients to contribute to fatigue and inflammation.

See also

• Amino acid
• Supplements

Learn more

• L-glutamine - Pubchem

glutamate (Glu) - Glutamate is one of the amino acids used by the body to make proteins. It is a salt or ester of glutamic acid, and the terms glutamate and glutamic acid are often used interchangeably. It also functions as the principal excitatory neurotransmitter in the brain.