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Helminthic therapy
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'''Helminthic therapy''' is the reintroduction to the digestive tract of a controlled number of specially domesticated, mutualistic helminths (intestinal worms) in the form of microscopic larvae or eggs to reconstitute a depleted microbiome to treat and prevent chronic [[inflammation]], [[autoimmune disease]] and other immunological disorders including [[allergy]]. ==Theory== Humans and our primate ancestors have hosted helminths for many millions of years, during which time we and our worms have coevolved to the point at which we now need some of them in order to maintain optimum immune function.<ref>http://www.manchester.ac.uk/aboutus/news/display/?id=5841</ref> There are many helminths that can cause disease but, in the early years of the twenty-first century, four safe, mutualistic helminth species were domesticated and have been made available commercially for use in therapy. * [https://helminthictherapywiki.org/wiki/index.php/The_history_of_helminthic_therapy The history of helminthic therapy] * [http://helminthictherapywiki.org/wiki/index.php/Introduction_to_helminthic_therapy Introduction to helminthic therapy] ==Evidence== There is no evidence from clinical trials to support the use of helminthic therapy in [[ME/CFS]]. However, there is anecdotal evidence suggesting that this therapy can provide a degree of relief in at least some cases. * [https://helminthictherapywiki.org/wiki/index.php/Helminthic_therapy_personal_stories#ME.2FCFS_.28Myalgic_encephalomyelitis_.2F_Chronic_fatigue_syndrome.29 Helminthic therapy personal stories: ME/CFS] There is considerable evidence, both from formal science and the anecdotal reports of self-treaters, to support the use of helminthic therapy in [[Autoimmune disease|autoimmune]], inflammatory and allergic diseases, some of which can occur concurrently with [[ME/CFS]]. * [http://helminthictherapywiki.org/wiki/index.php/Helminthic_therapy_research Helminthic therapy research] * [https://helminthictherapywiki.org/wiki/index.php/Helminthic_therapy_personal_stories Helminthic therapy personal stories] ==Safety== Helminthic therapy is very safe if used sensibly by knowledgeable individuals. * [http://helminthictherapywiki.org/wiki/index.php/Helminthic_therapy_safety Helminthic therapy safety] However, anyone with ME/CFS needs to take special care with dosing. * [https://helminthictherapywiki.org/wiki/index.php/Hookworm_dosing_and_response#Patients_with_some_conditions_need_to_start_with_just_3_larvae Patients with some conditions need to start with micro doses] * [https://helminthictherapywiki.org/wiki/index.php/Helminthic_therapy_and_ME/CFS#Helminth_dosing_for_ME/CFS Helminth dosing for ME/CFS] ==Costs & availability== For details about each of the currently available therapeutic helminths, and how they compare, see this page. * [http://helminthictherapywiki.org/wiki/index.php/Selecting_a_therapeutic_helminth Selecting a therapeutic helminth] The following link provides full details about the companies that sell these organisms and what they cost. * [http://helminthictherapywiki.org/wiki/index.php/Helminth_providers Providers of therapeutic helminths] Customer feedback about the service provided by these companies is available on a separate page. * [http://helminthictherapywiki.org/wiki/index.php/Helminth_provider_reviews Helminth provider reviews] ==Medical support== Helminthic therapy is currently not approved for use by doctors anywhere in the world, so few doctors are willing to condone it, fearing the loss of their license if they do. As a result of this, the therapy has been developed by patients who treat themselves. In 2015, the number of individuals worldwide who were self-treating with helminths was estimated at between 6,000 and 7,000. * [http://www.yourwildlife.org/wp-content/uploads/2015/05/galley-proof-v2.pdf Overcoming Evolutionary Mismatch by Self-Treatment with Helminths: Current Practices and Experience] In the vast majority of cases where patients are self-treating, their doctors are willing to continue to provide them with routine medical care while the patient arranges for, and pursues, helminthic therapy independently. * [http://helminthictherapywiki.org/wiki/index.php/Introduction_to_helminthic_therapy#Working_with_a_doctor Helminthic therapy: Working with a doctor] There are several health professionals with extensive experience of helminthic therapy who offer one-to-one educational consultations about the therapy. This service may be valuable to anyone wanting to understand if and how helminthic therapy self-treatment might be of value in improving their health. * [https://helminthictherapywiki.org/wiki/index.php/Helminthic_therapy_practitioners Helminthic therapy practitioners] ==Learn more== *[https://helminthictherapywiki.org/wiki/index.php/Helminthic_therapy_and_ME/CFS Helminthic therapy and ME/CFS] *[http://forums.phoenixrising.me/index.php?threads%2Fhelminths-me.33729%2F Helminths & ME] *[http://helminthictherapywiki.org/wiki/index.php/Selecting_a_therapeutic_helminth Selecting a therapeutic helminth] *[http://helminthictherapywiki.org/wiki/index.php/Helminth_providers Helminth providers] *[http://helminthictherapywiki.org/wiki/index.php/Helminthic_therapy_research Helminthic therapy research] *[http://helminthictherapywiki.org/wiki/index.php/Helminthic_therapy_in_the_media Helminthic therapy in the media] *[http://helminthictherapywiki.org/wiki/index.php/Helminthic_therapy_personal_stories Helminthic therapy personal stories] *[http://helminthictherapywiki.org The Helminthic Therapy wiki] *[https://drruscio.com/worms-the-next-probiotics-with-dr-william-parker/ Are Worms the Next Probiotic?] - Michael Ruscio interviews William Parker (includes podcast download link), Dr. Ruscio Radio *[https://helminthictherapywiki.org/wiki/index.php/Hook_me_up!_Treating_autoimmune_disease_with_hookworms Hook me up! Treating Autoimmune Disease with Hookworms] - A report on the successful use of hookworms to treat guttate psoriasis *[https://www.youtube.com/watch?v=yGqTPM10wrY Microbiome Research in Autism Spectrum Disorders] - YouTube video *[http://lifeonus.vhx.tv Life On Us: A Microscopic Safari]. A two hour, two-part video documentary. The second part has a lengthy segment on helminths and helminthic therapy starting from 15 minutes. - VHX (Free on Amazon Prime) *[https://www.amazon.com/kindle/dp/B06XK56T1G ''The Worms Inside Me: My experiment with helminthic therapy''] - book by Beth Anderson ==See also== *[[Microbiome]] *[[Probiotics]] ==References== {{Reflist}} [[Category:Potential treatments]] [[Category:Probiotics]]
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