Heparin

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Revision as of 14:21, April 28, 2018 by JenB (talk | contribs) (added histamine)

Heparin is an anticoagulant sometimes used in the treatment of Lyme disease.

Heparin is a naturally-occurring anticoagulant produced by basophils and mast cells. Heparin is also is widely used as an injectable anticoagulant.

Heparin increases the activity of diamine oxidase (DAO), the enzyme the breaks down histamine, in the bloodstream.[1]

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  1. Klocker, Josef; Perkmann, Reinhold; Klein-Weigel, Peter; Mörsdorf, Gabriele; Drasche, Astrid; Klingler, Anton; Fraedrich, Gustav; Schwelberger, Hubert G. (January 2004), "Continuous administration of heparin in patients with deep vein thrombosis can increase plasma levels of diamine oxidase", Vascular Pharmacology, 40 (6): 293–300, doi:10.1016/j.vph.2004.02.002, ISSN 1537-1891, PMID 15063833