Anonymous
Not logged in
Talk
Contributions
Create account
Log in
Search
Editing
Ketogenic diet
(section)
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Namespaces
Page
Discussion
More
More
Page actions
Read
Edit
Edit source
History
Warning:
You are not logged in. Your IP address will be publicly visible if you make any edits. If you
log in
or
create an account
, your edits will be attributed to your username, along with other benefits.
Anti-spam check. Do
not
fill this in!
==Risks & Side Effects== *The ketogenic diet was found to regulate [[Glucose|blood sugar]] but over the long term cause fat to accumulate in the [[liver]] in an animal model of Type II [[Diabetes]].<ref name="ZhangX2016" /> An open label, non-randomized, controlled study of the ketogenic diet in Type II Diabetes patients showed sustained long-term beneficial effects on multiple clinical markers of diabetes and cardiometabolic health at 2 years while utilizing less medication.<ref name=":0">{{Cite journal | last = Athinarayanan | first = Shaminie J. | last2 = Adams | first2 = Rebecca N. | last3 = Hallberg | first3 = Sarah J. | last4 = McKenzie | first4 = Amy L. | last5 = Bhanpuri | first5 = Nasir H. | last6 = Campbell | first6 = Wayne W. | last7 = Volek | first7 = Jeff S. | last8 = Phinney | first8 = Stephen D. | last9 = McCarter | first9 = James P. | date = 2019 | title=Long-Term Effects of a Novel Continuous Remote Care Intervention Including Nutritional Ketosis for the Management of Type 2 Diabetes: A 2-Year Non-randomized Clinical Trial | url = https://www.ncbi.nlm.nih.gov/pubmed/31231311|journal=Frontiers in Endocrinology|volume=10 | pages = 348|doi=10.3389/fendo.2019.00348|issn=1664-2392|pmc=6561315|pmid=31231311}}</ref> *Two children on the diet for [[refractory epilepsy]] had [[selenium]] deficiency which resulted in sudden cardiac death.<ref>[http://www.pedneur.com/article/S0887-8994(08)00399-8/abstract?cc=y= Sudden Cardiac Death in Association With the Ketogenic Diet - Pediatric Neurology - December 2008]</ref> *Up to 6% of those on a ketogenic diet may experience kidney stones.<ref name=":1">{{Cite journal | last = Hartman | first = Adam L. | last2 = Vining | first2 = Eileen P.G. | date = Jan 2007 | title = Clinical aspects of the ketogenic diet | url = https://www.ncbi.nlm.nih.gov/pubmed/17241206|journal=Epilepsia|volume=48|issue=1 | pages = 31–42|doi=10.1111/j.1528-1167.2007.00914.x|issn=0013-9580|pmid=17241206}}</ref> *Ketogenic diets may require additional supplemental nutrition to prevent deficiencies. Common deficiencies include calcium, zinc, selenium, and copper.<ref name=":1" /> *Ketogenic diets are not recommended for those with genetic primary carnitine deficiencies [including mutations in carnitine palmitoyl transferase (CPT) I or II and mitochondrial translocase] and fatty acid β-oxidation abnormalities (e.g., medium-chain acyl dehydrogenase deficiency). <ref>{{Cite journal | last = Stafstrom | first = Carl E. | last2 = Rho | first2 = Jong M. | date = 2012-04-09 | title = The Ketogenic Diet as a Treatment Paradigm for Diverse Neurological Disorders | url = https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321471/|journal=Frontiers in Pharmacology|volume=3|doi=10.3389/fphar.2012.00059|issn=1663-9812|pmc=3321471|pmid=22509165}}</ref> It is safe for those with mitochondrial defects in complexes I, II, and IV<ref>{{Cite journal | last = Kang | first = Hoon-Chul | last2 = Lee | first2 = Young-Mock | last3 = Kim | first3 = Heung Dong | last4 = Lee | first4 = Joon Soo | last5 = Slama | first5 = Abdelhamid | date = Jan 2007 | title = Safe and effective use of the ketogenic diet in children with epilepsy and mitochondrial respiratory chain complex defects | url = https://www.ncbi.nlm.nih.gov/pubmed/17241212|journal=Epilepsia|volume=48|issue=1 | pages = 82–88|doi=10.1111/j.1528-1167.2006.00906.x|issn=0013-9580|pmid=17241212}}</ref> and pyruvate dehydrogenase complex deficiency.<ref>{{Cite journal | last = Sofou | first = Kalliopi | last2 = Dahlin | first2 = Maria | last3 = Hallböök | first3 = Tove | last4 = Lindefeldt | first4 = Marie | last5 = Viggedal | first5 = Gerd | last6 = Darin | first6 = Niklas | date = 2017 | title=Ketogenic diet in pyruvate dehydrogenase complex deficiency: short- and long-term outcomes | url = https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306430/|journal=Journal of Inherited Metabolic Disease|volume=40|issue=2|pages=237–245|doi=10.1007/s10545-016-0011-5|issn=0141-8955|pmc=5306430|pmid=28101805}}</ref>
Summary:
Please make sure your edits are consistent with
MEpedia's guidelines
.
By saving changes, you agree to the
Terms of use
, and you irrevocably agree to release your contribution under the
CC BY-SA 3.0 License
and the
GFDL
. You agree that a hyperlink or URL is sufficient attribution under the Creative Commons license.
Cancel
Editing help
(opens in new window)
Navigation
Navigation
Skip to content
Main page
Browse
Become an editor
Random page
Popular pages
Abbreviations
Glossary
About MEpedia
Links for editors
Contents
Guidelines
Recent changes
Pages in need
Search
Help
Wiki tools
Wiki tools
Special pages
Page tools
Page tools
User page tools
More
What links here
Related changes
Page information
Page logs