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Low blood volume
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'''Low blood volume''' is a commonly found sign of [[ME/CFS]] and [[Postural orthostatic tachycardia syndrome|POTS]]. Low blood volume may be attributed to reduced manufacture of antidiuretic hormone (ADH). [https://www.ncbi.nlm.nih.gov/pubmed/19534728 Some researchers] link the lack of production to deconditioning, due to the fact that decreased ADH correlates to increased severity of symptoms. However, this does not necessarily indicate the 'third cause' is deconditioning. Many moderately active patients suffer from low blood volume and accompanying [[orthostatic intolerance]]. ==Notable studies== *[http://www.ncbi.nlm.nih.gov/pubmed/10910366 The roles of orthostatic hypotension, orthostatic tachycardia, and subnormal erythrocyte volume in the pathogenesis of the chronic fatigue syndrome.] *[http://circ.ahajournals.org/content/111/13/1574.long Renin-Aldosterone Paradox and Perturbed Blood Volume Regulation Underlying Postural Tachycardia Syndrome] *[http://www.ncbi.nlm.nih.gov/pubmed/19469714 Chronic fatigue syndrome: illness severity, sedentary lifestyle, blood volume and evidence of diminished cardiac function.] *[https://www.ncbi.nlm.nih.gov/pubmed/27401397 Down-regulation of renin-aldosterone and antidiuretic hormone systems in patients with myalgic encephalomyelitis/chronic fatigue syndrome.] *[https://www.ncbi.nlm.nih.gov/pubmed/20199497 Hormonal alterations in adolescent chronic fatigue syndrome.] ==Learn more== *[http://www.healthrising.org/forums/threads/the-blood-volume-paradox-in-chronic-fatigue-syndrome-me-cfs-and-pots.4704/ The Blood Volume Paradox in Chronic Fatigue Syndrome (ME/CFS) and POTS - Health Rising] *[https://www.healthrising.org/forums/resources/dr-david-bell-on-low-blood-volume-in-chronic-fatigue-syndrome.234/ Dr. David Bell on Low Blood Volume in Chronic Fatigue Syndrome] ==See also== *[[Small heart syndrome]] *[[Cardiac problems in ME/CFS]] *[[:Portal:Cardiovascular system|Cardiovascular system]] ==References== {{Reflist}} [[Category:Signs and symptoms]] [[Category:Cardiac signs and symptoms]]
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