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Lyme disease
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== Blood and other laboratory tests == === United States === * Two-step Laboratory Testing Process<ref>{{Cite web|url=http://www.cdc.gov/lyme/diagnosistesting/labtest/twostep/index.html | title = Two-step Laboratory Testing Process {{!}} Lyme Disease|website=[[Centers for Disease Control and Prevention]]|language=en-us|access-date=2018-09-03 | date = |last = | first = | authorlink = |archive-url=|archive-date=|url-status=}}</ref> * Types of Lyme Disease Tests<ref>{{Cite web|url=http://lymediseaseguide.org/types-of-lyme-disease-tests | title = Types of Lyme Disease Tests|last = | first = | date = May 27, 2011 | website = lymediseaseguide.org|language=en-US|archive-url=|archive-date=|url-status=|access-date=2018-09-03}}</ref> * Laboratory tests that are not recommended<ref>{{Cite web|url=http://www.cdc.gov/lyme/diagnosistesting/LabTest/OtherLab/index.html | title = Laboratory tests that are not recommended {{!}} Lyme Disease|website=[[Centers for Disease Control and Prevention]]|language=en-us|access-date=2018-09-03 | date = |last = | first = | authorlink = |archive-url=|archive-date=|url-status=}}</ref> * [https://www.usatoday.com/story/news/nation/2018/11/16/lyme-disease-congress-report-better-testing/2031063002/ Tests for Lyme disease don't work well enough to diagnose illness early, federal panel says]<ref>{{Cite news | url=https://www.usatoday.com/story/news/nation/2018/11/16/lyme-disease-congress-report-better-testing/2031063002/ | title = Tests for Lyme disease don't work well enough to diagnose illness early, federal panel says|last = Carino|first = Jerry | date = Nov 16, 2018|work=USA TODAY|access-date=2018-11-26|archive-url=|archive-date=|url-status=|language=en}}</ref> === United Kingdom === * BBC1 Lyme Disease Discussion - Some patients have waited up to 30 years for a correct diagnosis. [[National Health Service]] (NHS) services have only correctly identified the disease in a quarter of the patients. The blood tests are unreliable and often come back negative. The development of an accurate blood test is in need of research funding.<ref>{{Cite web|url=https://www.youtube.com/watch?v=R1-a8kowVkE&app=desktop | title = BBC1 Lyme Disease 27.02.2016|last = Loukas | first = Demetrios | date = Feb 27, 2016 | website = YouTube|publisher=Katherine Allman|via=|archive-url=|archive-date=|url-status=|access-date=}}</ref> * [[Department of Health and Social Care (UK)]] Testing for Lyme Disease<ref name=":0">{{Cite web|url=http://webarchive.nationalarchives.gov.uk/20130107105354/http://www.dh.gov.uk/prod_consum_dh/groups/dh_digitalassets/@dh/@en/documents/digitalasset/dh_106528.pdf | title=Testing for Lyme Disease|last = Donaldson | first = Liam | date = 2009 | website = webarchive.nationalarchives.gov.uk | page = 4|type=PDF|archive-url=|archive-date=|url-status=|access-date=}}</ref> === False positives === Several herpesviruses including [[varicella zoster virus]]<ref name="Feder1991">{{citation | last1 = Feder | first1 = HM Jr | authorlink = | last2 = Gerber | first2 = MA | authorlink2 = | last3 = Luger | first3 = SW | authorlink3 = | last4 = Ryan | first4 = RW | authorlink4 = | title = False-positive serologic tests for Lyme disease after varicella infection|journal=N Engl J Med|volume=325|issue=26 | page = 1886-7 | date = Dec 1991|pmid=1961232|url=http://www.ncbi.nlm.nih.gov/pubmed/1961232}}</ref><ref name="Woelfle1998">{{citation | last1 = Woelfle | first1 = J | authorlink = | last2 = Wilske | first2 = B | authorlink2 = | last3 = Haverkamp | first3 = F | authorlink3 = | last4 = Bialek | first4 = R | authorlink4 = | title = False-positive serological tests for Lyme disease in facial palsy and varicella zoster meningo-encephalitis|journal=Eur J Pediatr|volume=157|issue=1 | page = 953-4 | date = Nov 1998|pmid=9835449|url=http://www.ncbi.nlm.nih.gov/pubmed/9835449}}</ref>, [[cytomegalovirus]], [[Epstein-Barr virus]],<ref name="Goossens1999">{{citation | last1 = Goossens | first1 = HA | authorlink = | last2 = Nohlmans | first2 = MK | authorlink2 = | last3 = van den Bogaard | first3 = AE | authorlink3 = | title = Epstein-Barr virus and cytomegalovirus infections cause false-positive results in IgM two-test protocol for early Lyme borreliosis|journal=Infection|volume=27|issue=3 | page = 231 | date =May 1999|pmid=10378140|url=http://link.springer.com/article/10.1007%2FBF02561539}}</ref> and [[Herpes simplex virus#HSV-2|HSV-2]]<ref name="Strasfeld2005">{{citation | last1 = Strasfeld | first1 = L | authorlink = | last2 = Romanzi | first2 = L | authorlink2 = | last3 = Seder | first3 = RH | authorlink3 = | last4 = Berardi | first4 = VP | authorlink4 = | title = False-Positive Serological Test Results for Lyme Disease in a Patient with Acute Herpes Simplex Virus Type 2|journal=Clin Infect Dis|volume=41|issue=12 | page = 1826-1827 | date = 2005|pmid=16288417|doi=10.1086/498319|url=http://cid.oxfordjournals.org/content/41/12/1826.full}}</ref> may cause false positives on Lyme Disease tests. === News media on unapproved tests === * 2005, Unproved Lyme Disease Tests Prompt Warnings<ref>{{Cite news | url=http://www.nytimes.com/2005/08/23/health/policy/unproved-lyme-disease-tests-prompt-warnings.html?_r=0 | title = Unproved Lyme Disease Tests Prompt Warnings|last = Santora | first = Marc | first2 =Dan | last2 =Hurley|publisher =New York Times |access-date=2018-09-03|language=en}}</ref> - New York Times * 2013, Many tests to diagnose Lyme, but no proof they work<ref>{{Cite news | url=https://www.bostonglobe.com/lifestyle/health-wellness/2013/10/20/many-tests-diagnose-lyme-but-proof-they/ISjAcxmZxkk2disi94ENfI/story.html | title = Many tests to diagnose Lyme, but no proof they do|last = Daley|first = Beth | date = Oct 21, 2013|work=The Boston Globe|access-date=2018-09-03|archive-url=|archive-date=|url-status=|quote=}}</ref> - The Boston Globe * 2013, Lyme Culture Test Causes Uproar<ref>{{Cite web|url=http://www.medscape.com/viewarticle/778482 | title = Lyme Culture Test Causes Uproar | last = | first = | date = | website = Medscape |url-access=registration|archive-url=|archive-date=|url-status=|access-date=2018-09-03}}</ref> - Medscape * 2014, Federal Loopholes Compromise Lyme Disease Testing<ref>{{Cite news | url=http://news.wgbh.org/post/federal-loopholes-compromise-lyme-disease-testing | title = Federal Loopholes Compromise Lyme Disease Testing|last = Daley|first = Beth | date = 2014-06-17|work=WGBH 89.7|access-date=2018-09-03|archive-url=|archive-date=|url-status=|language=en}}</ref>
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