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Mast cell activation syndrome
(section)
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===Omalizumab=== [[Omalizumab]] is an anti-[[IgE]] monoclonal antibody approved for treating other allergic diseases. In a study of 55 French patients with mast cell disorders, 43 patients achieved a "best response" and 76.7% of the responding patients achieved a persistent response (three months or longer.)<ref name="aaaai2019">{{Cite web|url=https://www.aaaai.org/global/latest-research-summaries/New-Research-from-JACI-In-Practice/mast-cells | title = A new therapy to calm down mast cells | last = | first = | authorlink = | date = April 9, 2019 | website = American Academy of Allergy, Asthma & Immunology|archive-url=|archive-date=|url-status=|access-date=July 28, 2019}}</ref> Median time to first response was 2 months and median time to best response was 6 months. One severe adverse event occurred, with researchers suggesting this recommends initiating treatment in hospital, but otherwise found the safety profile acceptable.<ref name="aaaai2019" />
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