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Metabolic trap
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==Treatment== Dr. [[Ron Davis]] has stated that if the IDO metabolic trap hypothesis is true, then he believes that ME/CFS would be curable.{{citation needed}} Moreover, the cure would not require development of a new drug (which is both costly and time-consuming).{{citation needed}} However, development of a treatment has not yet begun as the hypothesis has not yet been confirmed. Importantly, Davis has expressed concern that patients may try to self-experiment with the kynurenine pathway because of the availability of substances like tryptophan on the open market. He cautioned that this is a dangerous pathway to experiment with, with particular risk of causing permanent autoimmunity which is not curable with present technology.<ref name="RonDavisNov2018">{{Cite web|url=https://www.youtube.com/watch?v=pFzOrknOylA&feature=youtu.be&list=PLl4AfLZNZEQPxjqF4ojAO3wdCFMeriNBK&t=663 | title = Ronald W. Davis, PhD {{!}} What's next? | last = Davis | first = Ronald | authorlink= | date = Nov 7, 2018 | website = YouTube|publisher=Open Medicine Foundation - OMF|archive-url=|archive-date=|url-status=|access-date=}}</ref>
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