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Michael Houghton
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[[File:Michael Houghton.png|200px|thumb|right|Source:ualberta.ca]] '''Michael Houghton''', PhD, is a Professor at the Department of Medical Microbiology & Immunology, University of Alberta, Edmonton, Alberta, Canada. He was the first to successfully identify and clone the [[Hepatitis C]] virus.<ref>http://www.cerc.gc.ca/chairholders-titulaires/houghton-eng.aspx</ref> His professional interests are the [[Hepatitis C]] virus, the Hepatitis B virus, and exploring if other chronic illnesses are caused or exacerbated by an acute or persistent viral infection.<ref>http://www.mmi.med.ualberta.ca/staff_students/michael_houghton.php</ref> Dr. Houghton and his virology team are working on a [[diagnostic biomarker|biomarker]] for [[myalgic encephalomyelitis]]/[[chronic fatigue syndrome]] (ME/CFS) using diagnostic [[cytokine]] patterns (specifically circulating interleukin (IL)-16, IL-7, and Vascular Endothelial Growth Factor A (VEGF-A).<ref name=":0" /> The team is also investigating if a novel pathogen is associated with a cluster of CFS patients.<ref>http://solvecfs.org/research/cfidsaa-research-program-for-researchers/michael-houghton/</ref> ==Awards== *Canada Excellence Research Chair in Virology at the University of Alberta<ref>http://www.mmi.med.ualberta.ca/staff_students/michael_houghton.php</ref> *2000, Albert Lasker Clinical Medical Research Award<ref>http://www.laskerfoundation.org/awards/</ref> ==Chronic Fatigue Syndrome Advisory Committee== Dr. Houghton served as a voting member of the [[Chronic Fatigue Syndrome Advisory Committee]] from 05/10/10 to 05/10/14.<ref name="Fall, 2010" /> ==Notable studies== *2011, No Evidence for [[XMRV]] Nucleic Acids, Infectious Virus or Anti-[[XMRV]] Antibodies in Canadian Patients with [[Chronic Fatigue Syndrome]]<ref>{{Cite journal | last = Steffen | first = Imke | authorlink = | last2 = Tyrrell | first2 = D. Lorne | authorlink2 = | last3 = Stein | first3 = Eleanor | authorlink3 = Eleanor Stein | last4 = Montalvo | first4 = Leilani | authorlink4 = | last5 = Lee | first5 = Tzong-Hae | authorlink5 = | last6 = Zhou | first6 = Yanchen | last7 = Lu | first7 = Kai | last8 = Switzer | first8 = William M. | last9 = Tang | first9 = Shaohua | last10 = Jia | first10 = Hongwei | authorlink10 = | last11 = Hockman | first11 = Darren | authorlink11 = | last12 = Santer | first12 = Deanna M. | authorlink12 = | last13 = Logan | first13 = Michael | author-link13 = | last14 = Landi | first14 = Amir | authorlink14 = Amir Landi | last15 = Law | first15 = John | author-link15 = | last16 = Houghton | first16 = Michael | author-link16 = Michael Houghton | last17 = Simmons | first17 = Graham | author-link17 = | date = 2011-11-17 | title = No Evidence for XMRV Nucleic Acids, Infectious Virus or Anti-XMRV Antibodies in Canadian Patients with Chronic Fatigue Syndrome|url=http://dx.plos.org/10.1371/journal.pone.0027870|journal=PLoS ONE|language=en|volume=6|issue=11| pages = e27870|doi=10.1371/journal.pone.0027870|issn=1932-6203|pmc=3219700|pmid=22114717|quote=|via=}}</ref> [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219700/ (Full Text)] *2012, Minimum data elements for research reports on [[chronic fatigue syndrome|CFS]].<ref name="Jason,Unger 2012" /> [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643273/ (Full text)] *2016, Reductions in circulating levels of [[Interleukin 16|IL-16]], [[Interleukin 7|IL-7]] and [[Vascular endothelial growth factor|VEGF]]-A in myalgic encephalomyelitis/chronic fatigue syndrome<ref name=":0">{{Cite journal | last = Landi|first = Abdolamir | authorlink = Amir Landi | last2 = Broadhurst | first2 = David | authorlink2 = | last3 = Vernon | first3 = Suzanne D. | authorlink3 = Suzanne Vernon | last4 = Tyrrell | first4 = D. Lorne J. | authorlink4 = | last5 = Houghton | first5 = Michael | authorlink5 = Michael Houghton | date = Feb 2016 | title = Reductions in circulating levels of IL-16, IL-7 and VEGF-A in myalgic encephalomyelitis/chronic fatigue syndrome|url=https://linkinghub.elsevier.com/retrieve/pii/S1043466615301071|journal=Cytokine|language=en|volume=78|issue=|pages=27β36|doi=10.1016/j.cyto.2015.11.018|quote=|via=}}</ref> [http://www.sciencedirect.com/science/article/pii/S1043466615301071 (Full text)] ==See also== *[[Amir Landi]] *[[Chronic Fatigue Syndrome Advisory Committee]] *[[Diagnostic biomarker]] ==Learn more== *[http://www.mmi.med.ualberta.ca/staff_students/michael_houghton.php Faculty Bio page] *[http://www.cerc.gc.ca/chairholders-titulaires/houghton-eng.aspx Canada Excellence Research Chairs] ==References== <references> <ref name="Fall, 2010">{{citation | author = HHS.gov | title = October 12 & 13, 2010 CFSAC Meeting | type = Roster | date = 2010 | url = http://wayback.archive-it.org/3919/20140324192901/http://www.hhs.gov/advcomcfs/meetings/minutes/viewattachment.pdf }}</ref> <ref name="Jason,Unger 2012">{{Citation | last1 = Jason | first1 = LA | authorlink1 = Leonard Jason | last2 = Unger | first2 = ER | authorlink2 = Elizabeth Unger | last3 = Dimitrakoff | first3 = JD | authorlink3 = Jordan Dimitrakoff | last4 = Fagin | first4 = AP | authorlink4 = | last5 = Houghton | first5 = M | authorlink5 = Michael Houghton | last6 = Cook | first6 = DB | authorlink6 = Dane Cook | last7 = Marshall | first7 = GD, Jr | authorlink7 = Gailen Marshall | last8 =Klimas | first8 = N | authorlink8 = Nancy Klimas | last9 = Snell | first9 = C | authorlink9 = Christopher Snell | title = Minimum data elements for research reports on CFS | journal = Brain, Behavior, Immunology | volume = 26 | issue = 3 | page = 401-6 | date = 2012 | pmid = 22306456 | doi = 10.1016/j.bbi.2012.01.014 }}</ref> </references> [[Category:Researchers]] [[Category:US researchers]] [[Category:Canada researchers]] [[Category:Alberta researchers]] [[Category:CFSAC members]]
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