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Moving Toward Answers in ME/CFS - NIH Director's Blog (2017)
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'''Moving Toward Answers in ME/CFS - NIH Director's Blog (2017)''' by Dr. [[Walter Koroshetz]] and Dr. [[Francis Collins]] about [[ME/CFS]], onset and symptoms, and biomedical research.<ref>[https://directorsblog.nih.gov/2017/03/21/moving-toward-answers-in-mecfs/ Moving Toward Answers in ME/CFS - NIH Director's Blog - Dr. Walter Koroshetz and Dr. Francis Collins - March 21, 2017]</ref> == Illness onset and symptoms == *A [[Flu-like illness|bad cold or the flu]] where a person does not recover *[[Malaise|Achy and exhausted]] *Unrelenting [[fatigue]] [[Unrefreshing sleep|not relieved by sleep]] *[[Exertion]] makes one worse *Forced to leave job or school, cannot participate in favorite activities *At times cannot get out of bed ''Excerpt'' :Imagine going to work or school every day, working out at the gym, spending time with family and friends—basically, living your life in a full and vigorous way. Then one day, you wake up, feeling sick. A bad cold maybe, or perhaps the [[Influenza|flu]]. A few days pass, and you think it should be over—but it’s not, you still feel achy and exhausted. Now imagine that you never get better— plagued by [[Chronic fatigue|unrelenting fatigue]] not relieved by sleep. Any exertion just makes you worse. You are forced to leave your job or school and are unable to participate in any of your favorite activities; some days you can’t even get out of bed. The worst part is that your doctors don’t know what is wrong and nothing seems to help.<ref>[https://directorsblog.nih.gov/2017/03/21/moving-toward-answers-in-mecfs/ Moving Toward Answers in ME/CFS - NIH Director's Blog - Dr. Walter Koroshetz and Dr. Francis Collins - March 21, 2017]</ref> == References biomedical research == *[[Cytokine]] *[[Metabolic]] and [[Dauer]] *Damaged Calcium Receptors [[National Centre for Neuroimmunology and Emerging Diseases#Potential biomarker|Potential biomarker]] *[[Immune system]] and autoimmune process ''Excerpt'' :A number of studies suggest that abnormalities in [[cellular metabolism]], a complex biological process that the body uses to create energy [3][4][5], may underlie ME/CFS. A recent study of [[Metabolic|metabolite]] pathways in blood samples from people with ME/CFS reported a signature suggestive of a hypometabolic condition, similar to a phenomenon biologists have studied in other organisms and refer to by the term “[[dauer]]” (a hibernation-like state) [5]. A number of other studies have suggested that changes in the [[immune system]] may play a causal role in ME/CFS [6][7][8], either due to a post-infectious autoimmune process or due to a unknown chronic infection.<ref>[https://directorsblog.nih.gov/2017/03/21/moving-toward-answers-in-mecfs/ Moving Toward Answers in ME/CFS - NIH Director's Blog - Dr. Walter Koroshetz and Dr. Francis Collins - March 21, 2017]</ref> == Recognizes studies, groups and workshops == *[[Institute of Medicine report]] ([[SEID]] criteria developed by this study) *[[Trans-NIH ME/CFS Working Group]] *[[Pathways to prevention report]] (P2P) == Learn more == *[[National Institutes of Health]] (NIH) *[[National Institute of Neurological Disorders and Stroke]] (NINDS) == References == {{Reflist}} [[Category:News articles]]
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