Anonymous
Not logged in
Talk
Contributions
Create account
Log in
Search
Editing
Paralysis
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Namespaces
Page
Discussion
More
More
Page actions
Read
Edit
Edit source
History
Warning:
You are not logged in. Your IP address will be publicly visible if you make any edits. If you
log in
or
create an account
, your edits will be attributed to your username, along with other benefits.
Anti-spam check. Do
not
fill this in!
'''Paralysis''' in medical terms refers to the loss of muscle function and sensation in part or most of the body resulting from illness, injury, medication, or poison. It can be localized or generalized, partial or complete, and temporary or permanent.<ref>{{Cite web|url=https://www.healthline.com/health/paralysis | title = Paralysis: Definition and Patient Education | date = 2013-09-13 | website = Healthline|language=en|access-date=2018-12-28}}</ref> Re-occuring temporary paralysis is known as [[periodic paralysis]]. [[Paresis]] is severe muscle weakness without paralysis. ==Presentation== ==Prevalence== In a 2001 Belgian study, 27.2% of patients meeting the [[Fukuda criteria]] and 33.2% of patients meeting the [[Holmes criteria]], in a cohort of 2073 [[Chronic fatigue syndrome|CFS]] patients, reported paralysis.<ref>{{Cite journal | last = De Becker | first = Pascale | authorlink = Pascale De Becker | last2 = McGregor | first2 = Neil | author-link2 = Neil McGregor | last3 = De Meirleir | first3 = Kenny | authorlink3 = Kenny De Meirleir| date = December 2001 | title = A definition‐based analysis of symptoms in a large cohort of patients with chronic fatigue syndrome|url=https://onlinelibrary.wiley.com/doi/full/10.1046/j.1365-2796.2001.00890.x?sid=nlm%3Apubmed|journal=Journal of Internal Medicine|volume=250|issue=3|pages=234–240|doi=10.1046/j.1365-2796.2001.00890.x|quote=|via=}}</ref> A follow-up 45 years after the [[1955 Royal Free Hospital outbreak]] of [[myalgic encephalomyelitis]] found that five patients had developed forms of partial paralysis.<ref name="Underhill2021">{{Cite journal | last = Underhill | first = Rosemary | authorlink = Rosemary Underhill | last2 = Baillod | first2 = Rosemarie | authorlink2 = | date = Jan 2021 | title = Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Organic Disease or Psychosomatic Illness? A Re-Examination of the Royal Free Epidemic of 1955|url=https://www.mdpi.com/1648-9144/57/1/12|journal=Medicina|language=en|volume=57|issue=1|pages=12|doi=10.3390/medicina57010012|pmc=PMC7824095|pmid=33375343|access-date=|quote=|via=}}</ref> ==Symptom recognition== Paralysis is not described in the [[International Consensus Criteria]] Primer for [[Myalgic encephalomyelitis|Myalgic Encephalomyelitis]], but the [[ion transportation]] problems that can cause it are recognized.<ref name="ICP2011primer">{{citation | last1 = Carruthers | first1 = BM | authorlink1 = Bruce Carruthers | last2 = van de Sande | first2 = MI | authorlink2 = Marjorie van de Sande | last3 = De Meirleir | first3 = KL | authorlink3 = Kenny de Meirleir | last4 = Klimas | first4 = NG | authorlink4 = Nancy Klimas | last5 = Broderick | first5 = G | authorlink5 = Gordon Broderick | last6 = Mitchell | first6 = T | authorlink6 = Terry Mitchell | last7 = Staines | first7 = D | authorlink7 = Donald Staines | last8 = Powles | first8 = ACP | authorlink8 = A C Peter Powles | last9 = Speight | first9 = N | authorlink9 = Nigel Speight | last10 = Vallings | first10 = R | authorlink10 = Rosamund Vallings | last11 = Bateman | first11 = L | authorlink11 = Lucinda Bateman | last12 = Bell | first12 = DS | authorlink12 = David Bell | last13 = Carlo-Stella | first13 = N | authorlink13 = Nicoletta Carlo-Stella | last14 = Chia | first14 = J | authorlink14 = John Chia | last15 = Darragh | first15 = A | authorlink15 = Austin Darragh | last16 = Gerken | first16 = A | authorlink16 = Anne Gerken | last17 = Jo | first17 = D | authorlink17 = Daehyun Jo | last18 = Lewis | first18 = DP | authorlink18 = Donald Lewis | last19 = Light | first19 = AR | authorlink19 = Alan Light | last20 = Light | first20 = KC | authorlink20 = Kathleen Light | last21 = Marshall-Gradisnik | first21 = S | authorlink21 = Sonya Marshall-Gradisnik | last22 = McLaren-Howard | first22 = J | authorlink22 = John McLaren-Howard | last23 = Mena | first23 = I | authorlink23 = Ismael Mena | last24 = Miwa | first24 = K | authorlink24 = Kunihisa Miwa | last25 = Murovska | first25 = M | authorlink25= Modra Murovska | last26 = Stevens | first26 = SR | authorlink26 = Staci Stevens | title = Myalgic encephalomyelitis: Adult & Paediatric: International Consensus Primer for Medical Practitioners | date = 2012 | isbn = 978-0-9739335-3-6 | url = http://www.investinme.org/Documents/Guidelines/Myalgic%20Encephalomyelitis%20International%20Consensus%20Primer%20-2012-11-26.pdf }}</ref> ==Notable studies== ==Possible causes== *There are known [[Channelopathy|ion channel dysfunctions]] (channelopathies) that can cause similar symptoms - eg [[Periodic paralysis|Hyperkalemic periodic paralysis]], [[Hypokalemic periodic paralysis|Hypokalemic period paralysis]], [[Hypokalemic sensory overstimulation]]. ==Potential treatments== Paralysis caused by ion channel problems often results from [[Electrolytes|electrolyte]] imbalance, so should resolve when this is corrected. For example, hypokalemic periodic paralysis results from low levels of the electrolyte potassium, and can be resolved by taking potassium. ==Learn more== [https://en.wikipedia.org/wiki/Hypokalemic_sensory_overstimulation Hypokalemic sensory overstimulation] - Wikipedia ==See also== *[[Periodic paralysis]] *[[Hypokalemic periodic paralysis]] *[[Channelopathy]] *[[Muscle fatigability]] *[[Severe and very severe ME]] *[[Paresis]] *[[Sensory overload]] ==References== {{reflist}} [[Category:Signs and symptoms]] [[Category:Muscular signs and symptoms]] [[Category:Musculoskeletal diseases and disorders]]
Summary:
Please make sure your edits are consistent with
MEpedia's guidelines
.
By saving changes, you agree to the
Terms of use
, and you irrevocably agree to release your contribution under the
CC BY-SA 3.0 License
and the
GFDL
. You agree that a hyperlink or URL is sufficient attribution under the Creative Commons license.
Cancel
Editing help
(opens in new window)
Templates used on this page:
Template:Citation
(
edit
)
Template:Cite journal
(
edit
)
Template:Cite web
(
edit
)
Template:Main other
(
edit
)
Template:Reflist
(
edit
)
Module:Check for unknown parameters
(
edit
)
Module:Citation/CS1
(
edit
)
Module:Citation/CS1/COinS
(
edit
)
Module:Citation/CS1/Configuration
(
edit
)
Module:Citation/CS1/Date validation
(
edit
)
Module:Citation/CS1/Identifiers
(
edit
)
Module:Citation/CS1/Utilities
(
edit
)
Module:Citation/CS1/Whitelist
(
edit
)
Module:No globals
(
edit
)
Navigation
Navigation
Skip to content
Main page
Browse
Become an editor
Random page
Popular pages
Abbreviations
Glossary
About MEpedia
Links for editors
Contents
Guidelines
Recent changes
Pages in need
Search
Help
Wiki tools
Wiki tools
Special pages
Page tools
Page tools
User page tools
More
What links here
Related changes
Page information
Page logs