Portal talk:Myalgic Encephalomyelitis/Intro

PEM timing -- ~Njt (talk) 20:45, August 12, 2022 (UTC)

Thanks for your contributions User:Johnnyd3. I reverted the change about post-exertional malaise that defined it as always delayed because a wide range of sources have found otherwise, researchers have found that some people with ME have a mix of immediate and delayed PEM, and some have mostly immediate PEM, although many people do have only delayed PEM. Researchers to have found this includes Chu's Deconstructing post-exertional malaise in myalgic encephalomyelitis/chronic fatigue syndrome: A patient-centered, cross-sectional survey (2018) and Leonard Jason's research into developing an assessment questionnaire for PEM. This issue of timing and delays has been discussed recently on Talk:Post-exertional malaise if you would like to contribute. On the portal pages we should be summarizing or using part of the topic page it links to, so References will be there. I think I recall in some research that delayed PEM was considered to be particularly characteristic of ME, although I can't recall the source (a small number of people with MS and Post-polio syndrome report post-exertional malaise). ~Njt (talk) 20:45, August 12, 2022 (UTC)

post-exertional malaise (PEM) - A notable exacerbation of symptoms brought on by small physical or cognitive exertions. PEM may be referred to as a "crash" or "collapse" and can last for days or weeks. Symptoms can include cognitive impairments, muscle pain, trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, and others.

post-exertional malaise (PEM) - A notable exacerbation of symptoms brought on by small physical or cognitive exertions. PEM may be referred to as a "crash" or "collapse" and can last for days or weeks. Symptoms can include cognitive impairments, muscle pain, trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, and others.