Anonymous
Not logged in
Talk
Contributions
Create account
Log in
Search
Editing
Post-exertional malaise
(section)
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Namespaces
Page
Discussion
More
More
Page actions
Read
Edit
Edit source
History
Warning:
You are not logged in. Your IP address will be publicly visible if you make any edits. If you
log in
or
create an account
, your edits will be attributed to your username, along with other benefits.
Anti-spam check. Do
not
fill this in!
=== Multiple sclerosis === According to a 2015 report by the National Academy of Medicine, the prevalence of PEM among ME/CFS patients varies from 69 to 100%, which is much higher than in other disease groups.<ref name="IOM2015" /> In a 1996 study by Komaroff et al. 13 of 25 MS-patients (52%) reported PEM<ref name="Komaroff1996">{{Cite journal | last = Komaroff | first = A. L. | last2 = Fagioli | first2 = L.R. | last3 = Geiger | first3 = A.M. | last4 = Doolittle | first4 = T.H. | last5 = Lee | first5 = J. | last6 = Kornish | first6 = R.J. | last7 = Gleit | first7 = M.A. |last8 = Guerriero | first8 = R.T. | date = Jan 1996 | title = An examination of the working case definition of chronic fatigue syndrome|url=https://www.ncbi.nlm.nih.gov/pubmed/8579088|journal=The American Journal of Medicine|volume=100|issue=1 | pages = 56–64|issn=0002-9343|pmid=8579088}}</ref>, a figure similar to what Jason et al. found with the DSQ PEM subscale in a cohort of 106 MS-patients.<ref name="Jason2017">{{Cite journal | last= Jason | first = L.A. | authorlink = Leonard Jason | last2 = Ohanian | first2 = D. | last3 = Brown | first3 = A. | last4 = Sunnquist | first4 = M. | authorlink4 = Madison Sunnquist | last5 = McManimen | first5 = S. | last6 = Klebek | first6 = L. | last7 = Fox | first7 = P. | last8 = Sorenson | first8 = M. | date = 2017 | title=Differentiating Multiple Sclerosis from Myalgic Encephalomyelitis and Chronic Fatigue Syndrome|url=https://www.ncbi.nlm.nih.gov/pubmed/29430570|journal=Insights in Biomedicine|volume=2|issue=2|doi=10.21767/2572-5610.10027|issn=2572-5610|pmc=5800741|pmid=29430570}}</ref> Both studies used a broad definition of PEM which focused on fatigue after exercise. Preliminary research suggests that adding more specific questions, for example about the prolonged recovery and various type of triggers, PEM might be able to differentiate ME/CFS from [[multiple sclerosis]]. A 2018 study for example showed that ME/CFS patients reported to experience PEM more often through mental exertion and to recover more slowly from PEM compared to multiple sclerosis patients.<ref name="Cotler2018" />
Summary:
Please make sure your edits are consistent with
MEpedia's guidelines
.
By saving changes, you agree to the
Terms of use
, and you irrevocably agree to release your contribution under the
CC BY-SA 3.0 License
and the
GFDL
. You agree that a hyperlink or URL is sufficient attribution under the Creative Commons license.
Cancel
Editing help
(opens in new window)
Navigation
Navigation
Skip to content
Main page
Browse
Become an editor
Random page
Popular pages
Abbreviations
Glossary
About MEpedia
Links for editors
Contents
Guidelines
Recent changes
Pages in need
Search
Help
Wiki tools
Wiki tools
Special pages
Page tools
Page tools
User page tools
More
What links here
Related changes
Page information
Page logs