Anonymous
Not logged in
Talk
Contributions
Create account
Log in
Search
Editing
Postural orthostatic tachycardia syndrome
(section)
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Namespaces
Page
Discussion
More
More
Page actions
Read
Edit
Edit source
History
Warning:
You are not logged in. Your IP address will be publicly visible if you make any edits. If you
log in
or
create an account
, your edits will be attributed to your username, along with other benefits.
Anti-spam check. Do
not
fill this in!
===ME/CFS === POTS can be a co-morbid condition in [[ME/CFS]] patients.<ref>{{Cite web|url=https://www.youtube.com/watch?v=o4OqNPZoqVs | title = POTS in ME/CFS | last = | first = | date = Aug 2, 2014 | website = Freedom From ME - The Optimum Health Clinic on YouTube|publisher=|archive-url=|archive-date=|url-status=|access-date= | authorlink = }}</ref><ref>{{Cite web|url=https://ammes.org/overlapping-conditions/ | title = Overlapping Conditions – American ME and CFS Society|website=ammes.org|language=en-US|access-date=2018-08-12}}</ref> Estimates on the prevalence of POTS among [[ME/CFS]] patients varies widely, from 11% to 70%. In a 2008 study done in the UK by the Northern CFS/ME Clinical Network, using the [[Fukuda criteria]], 27% of the study population had POTS compared with 9% in the control population.<ref name=":2">{{Cite journal | last = Hoad | first = A. | authorlink = | last2 = Spickett | first2 = G. | author-link2 = Gavin Spickett | last3 = Elliott | first3 = J. | author-link3 = | last4 = Newton | first4 = J. | author-link4 = Julia Newton | date = 2008 | title = Postural orthostatic tachycardia syndrome is an under-recognized condition in chronic fatigue syndrome | url = https://www.ncbi.nlm.nih.gov/pubmed/18805903 | journal = QJM: monthly journal of the Association of Physicians | volume = 101 | issue = 12 | pages = 961–965 | doi = 10.1093/qjmed/hcn123 | issn=1460-2393 | pmid = 18805903 | quote = | via = }}</ref> {| class="wikitable" ! colspan="3" |Prevalence of POTS in ME/CFS population samples |- !Study: !number of ME/CFS patients !% POTS |- |[[pubmed:10431117|Stewart et al. 1999]] |25 |70% |- |[[pubmed:10189122|Schondorf et al. 1999]] |75 |40% |- |[[pubmed:18805903|Hoad et al. 2008]] |59 |27% |- |[https://www.frontiersin.org/articles/10.3389/fped.2018.00349/full Van Campen et al. 2018] |627 |25% |- |Dowsett & Ramsay, 1990<ref>{{Cite journal | last = Dowsett | first=E. G. | last2 = Ramsay | first2 = A.M. | last3 = McCartney | first3 = R.A. | last4 = Bell | first4 = E.J. | date = Jul 1990 | title = Myalgic encephalomyelitis--a persistent enteroviral infection?|url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2429637/|journal=Postgraduate Medical Journal|volume=66|issue=777 | pages = 526–530|issn=0032-5473|pmc=2429637|pmid=2170962}}</ref> |420 |21% |- |[[pubmed:23206180|Lewis et al. 2013]] |179 |13% |- |[[pubmed:24206536|Reynolds et al. 2014]] |306 |11% |- |[[pubmed:27696568|Roerink et al. 2017]] |419 |5,7% |} A 2011 study of 58 POTS patients by the Vanderbilt Autonomic Dysfunction Center (Vanderbilt University School of Medicine, Nashville, TN, U.S.A.), reported that 64% of also met the [[Centers for Disease Control and Prevention]] (CDC) criteria for [[chronic fatigue syndrome]].<ref>{{Cite journal | last = Okamoto | first = Luis E. | last2 = Raj | first2 = Satish R. | last3 = Peltier | first3 = Amanda | last4 = Gamboa | first4 = Alfredo | last5 = Shibao | first5 = Cyndya | last6 = Diedrich | first6 = André | last7 = Black | first7 = Bonnie K. | last8 = Robertson | first8 = David | last9 = Biaggioni | first9 = Italo | date = 2012-02-01 | title = Neurohumoral and haemodynamic profile in postural tachycardia and chronic fatigue syndromes|url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203411/|journal=Clinical Science (London, England : 1979)|volume=122|issue=Pt 4|pages=183–192|doi=10.1042/CS20110200|issn=0143-5221|pmid=21906029|via=}}</ref> The [[SEID]] criteria requires either [[orthostatic intolerance]] (of which POTS is one type) or [[cognitive dysfunction]] for a diagnosis.<ref name="IOM2015">{{Cite book | last = Institute of Medicine | first = | date = 2015-03-16 | title = Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Redefining an Illness.|url=https://www.nap.edu/read/19012/chapter/6#114|language=en|volume=|at=Box 4-3, p 114|doi=10.17226/19012|via=NAP.edu|issue=|quote= | author-link = Institute of Medicine|publisher=The National Academies Press|location=Washington, DC}}</ref> POTS is also a symptom of the [[Canadian Consensus Criteria]] (CCC) which diagnoses ME/CFS,<ref>{{Cite web|url=http://me-pedia.org/wiki/Canadian_Consensus_Criteria#Definition | title = Canadian Consensus Criteria - MEpedia|website=me-pedia.org|language=en|access-date=2018-08-16}}</ref> and the [[International Consensus Criteria]] (ICC) for diagnosing [[myalgic encephalomyelitis]] (ME).<ref>{{Cite web|url=http://me-pedia.org/wiki/International_Consensus_Criteria#D._Energy_production.2Ftransportation_impairments:_At_least_one_symptom | title = International Consensus Criteria - MEpedia|website=me-pedia.org|language=en|access-date=2018-08-16}}</ref> However, the diagnosis of POTS alone does not automatically support a [[ME/CFS]] diagnosis and cannot be used as a [[diagnostic biomarker]] to determine ME/CFS. POTS can occur independent from ME/CFS, and, likewise, ME/CFS can occur without the symptomatology of POTS. A 2016 study in the Netherlands by Roerink et al., found that patients with CFS who fulfilled the [[SEID]] criteria did not have a prevalence of POTS different from that in the overall ME/CFS population. In adults with ME/CFS, the prevalence of POTS was low, between 6% - 18% (depending on age), was not different from the rate in non-ME/CFS fatigued patients, and was not related to disease severity or treatment outcome.<ref>{{Cite journal | last = Roerink | first = M. E. | last2 = Lenders | first2 = J. W.M. | last3 = Schmits | first3 = I.C. | last4 = Pistorius | first4 = A.M.A. | last5 = Smit | first5 = J.W. | last6 = Knoop | first6 = H. | last7 = van der Meer | first7 = J.W.M. | date = 2016-10-02 | title = Postural orthostatic tachycardia is not a useful diagnostic marker for chronic fatigue syndrome|url=https://doi.org/10.1111/joim.12564|journal=Journal of Internal Medicine|language=en|volume=281|issue=2|pages=179–188|doi=10.1111/joim.12564|issn=0954-6820|via= | authorlink7 = Jos van der Meer}}</ref> ME patients with POTS can experience impaired neurocognitive abilities (such as working memory, information processing) under increased orthostatic stress (i.e., standing, [[tilt table test]]).<ref>{{Cite journal | last = Ocon | first = Anthony J. | last2 = Messer | first2 = Zachary R. | last3 = Medow | first3 = Marvin S. | last4 = Stewart | first4 = Julian M. | date = Mar 2012 | title = Increasing orthostatic stress impairs neurocognitive functioning in chronic fatigue syndrome with postural tachycardia syndrome|url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368269/|journal=Clinical Science (London, England : 1979)|volume=122|issue=5|pages=227–238|doi=10.1042/CS20110241|issn=0143-5221|pmc=3368269|pmid=21919887|quote= | authorlink3 = Marvin Medow | author-link4 = Julian Stewart | author-link5 = |via=}}</ref>
Summary:
Please make sure your edits are consistent with
MEpedia's guidelines
.
By saving changes, you agree to the
Terms of use
, and you irrevocably agree to release your contribution under the
CC BY-SA 3.0 License
and the
GFDL
. You agree that a hyperlink or URL is sufficient attribution under the Creative Commons license.
Cancel
Editing help
(opens in new window)
Navigation
Navigation
Skip to content
Main page
Browse
Become an editor
Random page
Popular pages
Abbreviations
Glossary
About MEpedia
Links for editors
Contents
Guidelines
Recent changes
Pages in need
Search
Help
Wiki tools
Wiki tools
Special pages
Page tools
Page tools
User page tools
More
What links here
Related changes
Page information
Page logs