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Prognosis for myalgic encephalomyelitis and chronic fatigue syndrome
(section)
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=== Age === Although some studies have found the age of adult ME/CFS patients to be associated with poorer outcomes (with older people having a worse prognosis), most studies did not find this correlation (see table below). {| class="wikitable" | colspan="2" |<small>Does age impact prognosis?</small> |- |<small>Yes</small> |<small>No</small> |- |<small>Jason et al., 2011.<ref name="Jason2011" /></small> |<small>Bombardier et al., 1995.<ref name="Bombardier1995" /></small> |- |<small>Tiersky et al., 2002.<ref name="Tiersky2002" /></small> |<small>Vercoulen et al., 1996.<ref name="Vercoulen1996" /></small> |- | |<small>Pheley et al., 1999.<ref name="Pheley1999" /></small> |- |<small> </small> |<small>Reyes et al., 1999.<ref name="Reyes1999" /></small> |- |<small> </small> |<small>Ciccone et al., 2010.<ref name=":16" /></small> |} Matthews & [[Anthony Komaroff|Komaroff]] were able to follow-up on 92 ME/CFS patients for a long period of nine years. The authors noted that “physical function tended to improve for many patients over time, despite the fact that they were aging.” This suggests age is not a predictor of poor outcomes in adult ME/CFS patients.<ref name="Matthews2007">{{Cite journal | last = Matthews | first = Rosalind M. | last2 = Komaroff | first2 = Anthony L. | date = Jan 2007 | title = Changes in Functional Status in Chronic Fatigue Syndrome Over a Decade|url=https://www.tandfonline.com/doi/abs/10.1300/J092v14n01_04|journal=Journal of Chronic Fatigue Syndrome|language=en|volume=14|issue=1|pages=33–42|doi=10.1300/j092v14n01_04|issn=1057-3321}}</ref> Kidd et al. segmented ME/CFS patients into two groups: those younger and those older than 55. A comparison showed few meaningful differences. But when limited to those patients who had been sick for a long time, younger patients did have more [[Autonomic nervous system|autonomic]] and [[Immune system|immune]]-related symptoms.<ref>{{Cite journal | last = Kidd | first=Elizabeth | last2 = Brown | first2 = Abigail | last3 = McManimen | first3 = Stephanie | last4 = Jason | first4 = Leonard A. | last5 = Newton | first5 = Julia L. | last6 = Strand | first6 = Elin Bolle | date = 2016-04-22 | title = The Relationship between Age and Illness Duration in Chronic Fatigue Syndrome|url=https://www.ncbi.nlm.nih.gov/pubmed/27110826|journal=Diagnostics (Basel, Switzerland)|volume=6|issue=2|doi=10.3390/diagnostics6020016|issn=2075-4418|pmc=4931411|pmid=27110826}}</ref>
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