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Proline-rich transmembrane protein 4
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{{stub}} '''Proline-rich transmembrane protein 4''' or '''PRRT4''' is an obscure gene that may be linked to [[chronic fatigue syndrome]].<ref name ="Nathanson2019"/><ref name="genecards">https://www.genecards.org/cgi-bin/carddisp.pl?gene=PRRT4</ref > ==Function == ==ME/CFS == The first publication from the long term [[ME/CFS Gene Study]], which used the [[Fukuda criteria]] for [[chronic fatigue syndrome]] only, looked for the SNPs that were more common in CFS patients than in healthy people, and which were most likely to be harmful. PRRT4 was one of the top ten genes most likely to be harmful that more common in CFS patients, occurring in over 70% of patients.<ref name="Nathanson2019" /> == Notable studies == * 2019, Genetic Predisposition for Immune System, Hormone, and Metabolic Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Pilot Study<ref name="Nathanson2019">{{Cite journal | last = Nathanson | first = Lubov | authorlink = Lubov Nathanson | author-link2 = Travis Craddock | last2 = Craddock | first2 = Travis J.A. | last3 = Klimas | first3 = Nancy G. | authorlink3 = Nancy Klimas | authorlink4 = Kristina Gemayel | last4 = Gemayel | first4 = Kristina | last5 = Del Alamo | first5 = Ana | authorlink5 = Ana Del Alamo | authorlink6 = Kelly Hilton | last6 = Hilton | first6 = Kelly | last7 = Jaundoo | first7 = Rajeev | authorlink7 = Rajeev Jaundoo | last8 = Perez | first8 = Melanie | authorlink8 = Melanie Perez | date = 2019 | title=Genetic Predisposition for Immune System, Hormone, and Metabolic Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Pilot Study|url=https://www.frontiersin.org/articles/10.3389/fped.2019.00206/full|journal=Frontiers in Pediatrics|language=English|volume=7|issue=|pages=206|doi=10.3389/fped.2019.00206|issn=2296-2360}}</ref> [https://doi.org/10.3389/fped.2019.00206 (Full text)] ==See also == *[[ATP]] *[[Metabolism]] *[[ME/CFS Gene Study]] ==Learn more == *[https://www.genecards.org/cgi-bin/carddisp.pl?gene=PRRT4 PRRT4 - Genecards] ==References == [[Category:Genes]] [[Category:Biochemistry and cell biology]]
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