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Q fever
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==ME/CFS== Q fever is known to trigger chronic fatigue in some patients, often referred to as Q Fever Fatigue Syndrome (QFS).<ref name="Keijmel2015" /> A 2006 prospective study found that 11% of subjects infected with Q fever met the criteria for [[chronic fatigue syndrome]] six months after their infection. (The same rate held true for [[Epstein-Barr virus]] and [[Ross River virus]]).<ref>{{Cite journal | last = Hickie | first = Ian | last2 = Davenport | first2 = Tracey | last3 = Wakefield | first3 = Denis | last4 = Vollmer-Conna | first4 = Ute | last5 = Cameron | first5 = Barbara | last6 = Vernon | first6 = Suzanne D. | last7 = Reeves | first7 = William C. | last8 = Lloyd | first8 = Andrew | last9 = Dubbo Infection Outcomes Study Group| date = 2006-09-16| title = Post-infective and chronic fatigue syndromes precipitated by viral and non-viral pathogens: prospective cohort study|url=https://www.ncbi.nlm.nih.gov/pubmed/16950834|journal=BMJ (Clinical research ed.)|volume=333|issue=7568|pages=575|doi=10.1136/bmj.38933.585764.AE|issn=1756-1833|pmc=1569956|pmid=16950834|quote= | author-link = Ian Hickie | authorlink2 = Tracey Davenport|access-date= | authorlink3 = Denis Wakefield | author-link4 = UtΓ© Vollmer-Conna | authorlink5 = | authorlink6 = Suzanne Vernon|via= | authorlink7 = William Reeves | authorlink8 = Andrew Lloyd}}</ref> In a 2015 study, QFS patients were compared with [[chronic fatigue syndrome]] (CFS) patients: "In all analyses QFS patients were as fatigued and distressed as CFS patients, but reported less additional symptoms. QFS patients had stronger somatic attributions, and higher levels of physical activity. No differences were found with regard to inflammatory markers and in other fatigue-related cognitive-behavioral variables."<ref name="Keijmel2015">{{Cite journal | last = Keijmel | first = Stephan P. | author-link = | last2 = Saxe | first2 = Johanna | authorlink2 = | last3 = van der Meer | first3 = Jos W. M. | authorlink3 = Jos van der Meer | last4 = Nikolaus | first4 = Stephanie | authorlink4 = | last5 = Netea | first5 = Mihai G. | authorlink5 = | last6 = Bleijenberg | first6 = Gijs | authorlink6 = Gijs Bleijenberg | last7 = Bleeker-Rovers | first7 = Chantal P. | authorlink7 = Chantal Bleeker-Rovers | last8 = Knoop | first8 = Hans | authorlink8 = | date = Oct 2015 | title = A comparison of patients with Q fever fatigue syndrome and patients with chronic fatigue syndrome with a focus on inflammatory markers and possible fatigue perpetuating cognitions and behaviour |url =https://www.ncbi.nlm.nih.gov/pubmed/26272528|journal=Journal of Psychosomatic Research|volume=79|issue=4|pages=295β302|doi=10.1016/j.jpsychores.2015.07.005|issn=1879-1360|pmid=26272528|quote=|via=|pmc=|access-date=}}</ref> A 2020 study done in the Netherlands studied patterns of the gut [[microbiome]], blood metabolome, and inflammatory proteome of QFS patients, and compared these with those of chronic fatigue syndrome (CFS) patients and healthy controls (HC). They found that although QFS patients show more of an inflammatory profile than CFS patients and HC, when comparing QFS patients to CFS patients, there is a striking resemblance and hardly any significant differences in microbiome taxonomy are found.<ref name=":1" /> Dr. [[Dragan Ledina]] writes about Q fever and [[ME/CFS]].<ref>{{Cite web|url=http://www.investinme.org/Article-270%20Chronic%20Fatigue%20Syndrome%20After%20Q%20fever.htm| title = Chronic Fatigue Syndrome after Q fever | last=Ledina | first=Dragan | authorlink=Dragan Ledina | date = |website=[[Invest in ME]]|archive-url=|archive-date=|url-status=|access-date=2019-01-12}}</ref>
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