Sharni Hardcastle

Source: ResearchGate

Sharni Lee Hardcastle, BBioMedSc (Hons1) PhD, is a researcher and Immunology Lecturer at National Centre for Neuroimmunology and Emerging Diseases, Griffith University, School of Medical Science, Brisbane, Queensland, Australia.

Awards

• 2010, Award: Co-Author of Best Poster at the International Science Symposium for CFS/ME
• 2013, Gold Coast Women in Business Award - Empowering Young Women’s Award In recognition of significant leadership potential and outstanding qualities and performance.
• 2016, Junior Investigator Award to encourage young CFS/FM researchers in recognition of their work awarded by IACFSME.

Notable studies

• 2012, Longitudinal investigation of natural killer cells and cytokines in chronic fatigue syndrome/myalgic encephalomyelitis
• 2012, The Effects of Influenza Vaccination on Immune Function in Patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (Full Text)
• 2014, The Role of Adaptive and Innate Immune Cells in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (Full Text)
• 2014, Characterization of Natural Killer Cell Phenotypes in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (Full Text)
• 2014, Analysis of the Relationship between Immune Dysfunction and Symptom Severity in Patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) (Full Text)
• 2015, Serum Immune Proteins in Moderate and Severe Chronic Fatigue Syndrome/Myalgic Encephalomyelitis Patients (Full Text)
• 2015, Characterisation of cell functions and receptors in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) (Full Text)
• 2015, Longitudinal analysis of immune abnormalities in varying severities of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis patients (Full Text)
• 2017, Impaired calcium mobilization in natural killer cells from chronic fatigue syndrome/myalgic encephalomyelitis patients is associated with transient receptor potential melastatin 3 ion channels (Full Text)

Talks and interviews

• 2013, The 2nd International Symposium for Chronic Fatique Syndrome/Myalgic Encephalomyelitis Presented: "The immunological profile of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis"
• 2014, International Student Research Forum, Denmark. Sharni Hardcastle represented National Centre for Neuroimmunology and Emerging Diseases and gave both an oral and poster presentation about her CFS/ME research.

Online presence

• PubMed
• Twitter
• Facebook
• Website
• ResearchGate

Learn more

• National Centre for Neuroimmunology and Emerging Diseases Website

See also

• National Centre for Neuroimmunology and Emerging Diseases
• Donald Staines
• Sonya Marshall-Gradisnik

serum The clear yellowish fluid that remains from blood plasma after clotting factors have been removed by clot formation. (Blood plasma is simply blood that has had its blood cells removed.)

myalgic encephalomyelitis (M.E.) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.