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Papers to add Muscle fibre characteristics and lactate responses to exercise in chronic fatigue syndrome https://jnnp.bmj.com/content/64/3/362.short Aerobic work capacity in patients with chronic fatigue syndrome https://www.bmj.com/content/301/6758/953.short ---- The page is getting pretty long. We need to think of a different way to approach quotations, especially opinion. --[[User:JenB|JenB]] ([[User talk:JenB|talk]]) 21:46, 21 April 2018 (PDT) ==Notable quotations== ===[[Mark VanNess]]=== <blockquote>"Our studies clearly show that dynamic exercise like walking or jogging exacerbates symptoms associated with ME/CFS."<ref>http://sallyjustme.blogspot.com/2015/01/dr-vanness-on-recent-press-reports.html</ref></blockquote> ===[[Paul Cheney]]=== <blockquote>"The whole idea that you can take a disease like this and exercise your way to health is foolishness. It is insane."<ref>2010 Invest in ME International ME Conference </ref> </blockquote> <blockquote>"The most important thing about exercise is not to have (patients with ME/CFS) do aerobic exercise. I believe that even progressive aerobic exercise is counter-productive. If you have a defect in mitochondrial function and you push the mitochondria by exercise, you kill the DNA."<ref>Lecture in Orlando, Florida, International Congress of Bioenergetic Medicine, 5th-7th February 1999</ref></blockquote> ===[[Peter Behan]]=== <blockquote>There is "... general agreement that (ME’s) distinguishing characteristic is severe muscle fatigability, made worse by exercise. It becomes apparent that any kind of muscle exercise can cause patients to be almost incapacitated (and) the patient is usually confined to bed."<ref>1988 Crit Rev Neurobiol: 1988:4:2:157-178</ref> </blockquote> ===M.S. Riley, et al=== <blockquote>"The patients with the chronic fatigue syndrome had a reduced exercise capacity compared with that of the other subjects, spending a significantly shorter time on the treadmill. They had a significantly higher heart rate at submaximal levels of exertion and at stage III exertion had significantly higher blood lactate concentrations."<ref name="Riley,1990"/></blockquote> ---- I wonder if we can come up with an alternative to "Appropriate exercise" It sounds like a value judgment and even though we don't think graded exercise works and a lot of the research on graded exercise has been poor quality, we also don't know that it doesn't work in the sense that there isn't as far as I am aware any peer reviewed literature demonstrating a negative or null result. Or that that the "appropriate" exercise the clinicians are recommending does. The key distinction is exercise that tries to remain within some kind of boundary ("energy envelope," heart rate) versus exercise that doesn't. Is there a name for a school of exercise that marries exercise with pacing? --[[User:JenB|JenB]] ([[User talk:JenB|talk]]) 06:37, 18 November 2015 (PST) We could perhaps add this http://www.jacobspublishers.com/images/Physiology/J_J_Physiology_1_2_007.pdf [[User:Olliec|Olliec]] ([[User talk:Olliec|talk]]) 07:46, 24 November 2015 (PST) Another study to consider adding is Cochrane, not sure where to put it atm so putting it here for now https://www.ncbi.nlm.nih.gov/pubmed/26852189 [[User:Olliec|Olliec]] ([[User talk:Olliec|talk]]) 05:24, 17 February 2016 (PST) Another resources is this list of quotations from Williams & Hooper, which contains many about exercise http://www.meactionuk.org.uk/Quotable_Quotes_Updated.pdf [[User:Olliec|Olliec]] ([[User talk:Olliec|talk]]) 07:35, 16 August 2016 (PDT) I am going to go on record as saying exercise in a clinical setting based on theory not yet thoroughly researched and proven is wrong. The very "thing" that damages the health of patients further should not be employed on a clinical level unless their is PROOF that it will not hurt them; these so called thresholds are not proven in double blind and replicated studies. Exercise, in order to bring on [[PEM]] in order to research it OR trying to find if there is a way for a patient to ever exercise and finding a research proven threshold or finding when a patient is in a true remission which probably exists but not for all patients, should only be employed in highly controlled research. It doesn't matter if it is not used as a treatment or cure for the patient, what matters is why it would be used outside of highly controlled research at this time.--[[User:DxCFS|DxCFS]] ([[User talk:DxCFS|talk]]) 11:57, 22 August 2016 (PDT) --[[User:DxCFS|DxCFS]] ([[User talk:DxCFS|talk]]) 15:03, 22 August 2016 (PDT) Excellent point! [[User:Kmdenmark|Kmdenmark]] ([[User talk:Kmdenmark|talk]]) 15:34, 22 August 2016 (PDT) :Additionally, I fail to understand how mental exertion which triggers PEM has anything to do with measuring VO2, but I'm stupid like that. I'm sure there is a theory, but we are back to theory and not solid research. Theory should not be implemented on patients in a clinical setting.--[[User:DxCFS|DxCFS]] ([[User talk:DxCFS|talk]]) 14:54, 22 August 2016 (PDT) Another excellent point! 15:34, 22 August 2016 (PDT) ---- I have moved citations not used in prior text from references section to here. If you can figure out where in the article these citations should be used, please move them back.--[[User:Samsara|Samsara]] ([[User talk:Samsara|talk]]) 08:33, 7 November 2016 (PST) <ref name="Nijs2011"> {{Citation | last1 = Nijs | first1 = J | authorlink1 = J Nijs | last2 = Aelbrecht | first2 = S | authorlink2 = S Aelbrecht | last3 = Meeus | first3 = M | authorlink3 = M Meeus | last4 = Van Oosterwijck | first4 = J | authorlink4 = J Van Oosterwijck | last5 = Zinzen | first5 = E | authorlink5 = E Zinzen | last6 = Clarys | first6 = P | authorlink6 = P Clarys | title = Tired of being inactive: a systematic literature review of physical activity, physiological exercise capacity and muscle strength in patients with chronic fatigue syndrome | journal = Disability and Rehabilitation | volume = | issue = | page = | date = 2011 | pmid = 21166613 | doi = 10.3109/09638288.2010.541543 }}</ref> <ref name="Learmonth2014"> {{Citation | last1 = Learmonth | first1 = YC | authorlink1 = YC Learmonth | last2 = Paul | first2 = L | authorlink2 = L Paul | last3 = McFadyen | first3 = AK | authorlink3 = AK McFadyen | last4 = Marshall-McKenna | first4 = R | authorlink4 = R Marshall-McKenna | last5 = Mattison | first5 = P | authorlink5 = P Mattison | last6 = Miller | first6 = L | authorlink6 = L Miller | last7 = McFarlane | first7 = NG | authorlink7 = NG McFarlane | display-authors = 7 | title = Short-term effect of aerobic exercise on symptoms in multiple sclerosis and chronic fatigue syndrome: a pilot study | journal = Int J MS Care | volume = | issue = | page = | date = Summer 2014 | pmid = 25061431 | doi = 10.7224/1537-2073.2013-005 }}</ref> <ref name="Riley,1990">{{Citation | last1 = Riley | first1 = MS | authorlink1 = | last2 = O’Brien | first2 = CJ | authorlink2 = | last3 = McCluskey | first3 = DR | authorlink3 = | last4 = Bell | first4 = NP | authorlink4 = | last5 = Nicholls | first5 = DP | authorlink5 = | title = Aerobic work capacity in patients with chronic fatigue syndrome | journal = British Medical Journal | volume = 301 | issue = 6758 | page = 953-956 | date = 1990 | pmid = 1664147 | url = http://www.bmj.com/content/301/6758/953 }}</ref> <ref name="Rowe2016"> {{Citation | last1 = Rowe | first1 = PC | authorlink1 = PC Rowe | last2 = Fontaine | first2 = KR | authorlink2 = KR Fontaine | last3 = Lauver | first3 = M | authorlink3 = M Lauver | last4 = Jasion | first4 = SE | authorlink4 = SE Jasion | last5 = Marden | first5 = CL | authorlink5 = CL Marden | last6 = Moni | first6 = M | authorlink6 = M Moni | last7 = Thompson | first7 = CB | authorlink7 = CB Thompson | last8 = Violand | first8 = VL | authorlink8 = VL Violand | display-authors = 8 | title = Neuromuscular Strain Increases Symptom Intensity in Chronic Fatigue Syndrome | journal = PLOS One | volume = | issue = | page = | date = July 2016 | pmid = 27428358 | doi = 10.1371/journal.pone.0159386 }}</ref> ---- This study can probably be added here too https://www.ncbi.nlm.nih.gov/pubmed/28782878 [[User:Ollie|Ollie]] ([[User talk:Ollie|talk]]) 04:46, 10 August 2017 (PDT) Perhaps <ref name="Riley,1990"> citation can be removed altogether as it is over 30 years old. [[User:Karen|Kmdenmark]]([[User talk:Kmdenmark|talk]]) 11:23, 25 April 2018 (EST)
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