Travis Craddock

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Travis J. A. Craddock, PhD, is an Associate Professor in the Departments of Psychology & Neuroscience, Computer Science and Clinical Immunology at Nova Southeastern University (NSU) in Fort Lauderdale, Florida. He serves as the Director of the Clinical Systems Biology Group at NSU’s Institute for Neuro-Immune Medicine where he researches complex chronic illness involving neuroinflammation, such as Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Gulf War Illness.[1]

Talks and interviews[edit | edit source]

Notable studies in ME/CFS[edit | edit source]

  • 2014, A Role for Homeostatic Drive in the Perpetuation of Complex Chronic Illness: Gulf War Illness and Chronic Fatigue Syndrome[2] - (Full Text)
  • 2015, Using gene expression signatures to identify novel treatment strategies in gulf war illness[3] - (Full text)
  • 2018, High-fidelity discrete modeling of the HPA axis: a study of regulatory plasticity in biology[4] - (Abstract)
  • 2019, Leveraging Prior Knowledge of Endocrine Immune Regulation in the Therapeutically Relevant Phenotyping of Women With Chronic Fatigue Syndrome[5] - (Abstract)
  • 2019, Treatment Avenues in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Split-gender Pharmacogenomic Study of Gene-expression Modules[6] - (Abstract)
  • 2019, From biomarkers to targeted treatment: The myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and gulf war illness (GWI) story[7] - (Abstract)
  • 2019, Pharmaceutical Interventions in Chronic Fatigue Syndrome: A Literature-based Commentary[8] - (Abstract)
  • 2019, Genetic Predisposition for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Pilot Study[9] - (Abstract)

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]

  1. ↑ University, Nova Southeastern. "Travis J.A. Craddock | College of Psychology". NSU. Retrieved April 23, 2019.
  2. ↑ Craddock, Travis J.A.; Fritsch, Paul; Rice, Jr, Mark A.; del Rosario, Ryan M.; Miller, Diane B.; Fletcher, Mary Ann; Klimas, Nancy G.; Broderick, Gordon (2014). "A Role for Homeostatic Drive in the Perpetuation of Complex Chronic Illness: Gulf War Illness and Chronic Fatigue Syndrome". PLOS One. 9 (1): e84839. doi:10.1371/journal.pone.0084839.
  3. ↑ Craddock, Travis J.A.; Harvey, Jeanna M.; Nathanson, Lubov; Barnes, Zachary M.; Klimas, Nancy G.; Fletcher, Mary Ann; Broderick, Gordon (July 9, 2015). "Using gene expression signatures to identify novel treatment strategies in gulf war illness". BMC Medical Genomics. 8. doi:10.1186/s12920-015-0111-3. ISSN 1755-8794. PMC 4495687. PMID 26156520.
  4. ↑ Sedghamiz, Hooman; Morris, Matthew; Craddock, Travis J.A.; Whitley, Darrell; Broderick, Gordon (July 17, 2018). "High-fidelity discrete modeling of the HPA axis: a study of regulatory plasticity in biology". BMC Systems Biology. 12 (76). doi:10.1186/s12918-018-0599-1.
  5. ↑ Morris, Matthew C.; Cooney, Katherine E.; Sedghamiz, Hooman; Abreu, Maria; Collado, Fanny; Balbin, Elizabeth G.; Craddock, Travis J.A.; Klimas, Nancy G.; Broderick, Gordon; Fletcher, Mary Ann (March 2019). "Leveraging Prior Knowledge of Endocrine Immune Regulation in the Therapeutically Relevant Phenotyping of Women With Chronic Fatigue Syndrome". Clinical Therapeutics. doi:10.1016/j.clinthera.2019.03.002.
  6. ↑ Jeffrey, Mary G.; Nathanson, Lubov; Aenlle, Kristina; Barnes, Zachary M.; Baig, Mirza; Broderick, Gordon; Klimas, Nancy G.; Fletcher, Mary Ann; Craddock, Travis J.A. (March 2019). "Treatment Avenues in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Split-gender Pharmacogenomic Study of Gene-expression Modules". Clinical Therapeutics. doi:10.1016/j.clinthera.2019.01.011.
  7. ↑ Klimas, N.G.; Fletcher, M.A.; Abreu, M.M.; Aenlle, K.; Craddock, T.; Broderick, G. (February 2019). "From biomarkers to targeted treatment: The myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and gulf war illness (GWI) story". Brain, Behavior, and Immunity. 76: e40. doi:10.1016/j.bbi.2018.11.301.
  8. ↑ Richman, Spencer; Morris, Matthew C.; Broderick, Gordon; Craddock, Travis J.A.; Klimas, Nancy G.; Fletcher, Mary Ann (March 2019). "Pharmaceutical Interventions in Chronic Fatigue Syndrome: A Literature-based Commentary". Clinical Therapeutics. doi:10.1016/j.clinthera.2019.02.011.
  9. ↑ Perez, Melanie; Jaundoo, Rajeev; Hilton, Kelly; Del Alamo, Ana; Gemayel, Kristina; Klimas, Nancy G.; Craddock, Travis J.; Nathanson, Lubov (May 2019). "Genetic Predisposition for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Pilot Study". Frontiers in Pediatrics. 7: 206. doi:10.3389/fped.2019.00206.

chronic illness any long-term illness, regardless of the severity. Chronic illnesses are typically incurable, requiring long-term management.

myalgic encephalomyelitis (M.E.) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.

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