Empty sella syndrome

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In empty sella syndrome (ESS), the pituitary gland shrinks or becomes flattened, filling the sella turcica with cerebrospinal fluid on imaging instead of the normal pituitary. The reported prevalence of primary empty sella in general population is 8–35 %, with a higher incidence in females, the ratio being 5:1.[1] It is generally found in middle aged women who are obese and hypertensive. It is unknown whether this is causal or a consequence of hormonal abnormalities arising from pituitary changes. However, most people with ESS are asymptomatic.[2]

A finding of ESS on an MRI may be an indication of intracranial hypertension, particular if symptoms of intracranial pressure are present.[3]

References[edit | edit source]

  1. Aruna, P (April 2014). "Partial Empty Sella Syndrome: A Case Report and Review". Indian Journal of Biochemistry. 
  2. "Empty Sella Syndrome". National Organization for Rare Disorders. 
  3. Saindane1, Amit (May 2013). "Factors Determining the Clinical Significance of an "Empty" Sella Turcica". American Journal of Roentgenology. 


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From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history