File:MEupregulatedgenes.png

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Summary[edit | edit source]

Title: (or description)[edit | edit source]

Top 3 upregulated genes found in Myalgic Encephalomyelitis patients, compared to controls.

Author: (or citation)[edit | edit source]

Sweetman et al. Current Research Provides Insight into the Biological Basis and Diagnostic Potential for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Diagnostics 2019 9(3) 73; doi.org/10.3390/diagnostics9030073

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https://www.mdpi.com/2075-4418/9/3/73

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myalgic encephalomyelitis (M.E.) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.

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current12:19, July 22, 2019Thumbnail for version as of 12:19, July 22, 20193,329 × 2,295 (242 KB)Notjusttired (talk | contribs)Top 3 upregulated genes found in Myalgic Encephalomyelitis patients, compared to controls. Citation: Current Research Provides Insight into the Biological Basis and Diagnostic Potential for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) D...

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