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Neopterin
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==Function== Neopterin is also a metabolite of guanosine triphosphate (GTP) that is produced by a type of white blood cell known as [[macrophage]]s after [[interferon gamma|IFN-γ]] stimulation.<ref name="DictRheumatology">{{Cite book | title = Dictionary of Rheumatology|isbn=978-3-319-21335-4|language=en | url =https://books.google.co.uk/books?id=d_TuCgAAQBAJ&pg=PA217&dq=neopterin+dictionary&hl=en& | date = 2015-11-16|publisher=Springer | last = Rovenský | first = Jozef | last2 = Payer | first2 = Juraj | last3 = Herold | first3 = Manfred}}</ref> Research on brains affected by Alzheimer's disease has shown levels of neopterin are five times higher than in healthy brains. Some evidence suggests that microglia may produce neopterin during physiological stress, and that neopterin may have a protective role in response to damage or inflammation.<ref name="scidir-2098">{{Cite book | last = Colette Daubner | first = S. | last2 = Lanzas | first2 = Ronald O. | date = 2018-01-01 | title = Pteridines☆|url=https://www.sciencedirect.com/science/article/pii/B9780128012383662098|language=en|publisher=Elsevier|isbn=978-0-12-801238-3}}</ref>
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