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Fluoxetine
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'''Fluoxetine''', also known by brand names '''Prozac''' and '''Sarafem''' among others, is an antidepressant of the [[selective serotonin reuptake inhibitor]] (SSRI) class. It is used for [[depression]], [[anxiety]], [[panic]], [[Anorexia_and_eating_disorders#Bulimia|bulimia nervosa]], [[obsessive-compulsive disorder]] (OCD) and [[premenstrual dysphoric disorder]] (PDD).<ref name=drugscom /> It has shown potential antiviral activity against [[Coxsackie B4]].<ref>{{Citation| doi = 10.1016/j.antiviral.2015.01.010| issn = 1872-9096| volume = 116| pages = 51β54| last1 = Alidjinou | first1 = Enagnon Kazali | last2 = SanΓ©| first2 = Famara | last3 = Bertin | first3 = Antoine | last4 = Caloone | first4 = Delphine | last5 = Hober | first5 = Didier| title = Persistent infection of human pancreatic cells with Coxsackievirus B4 is cured by fluoxetine| journal = Antiviral Research| date = April 2015 | pmid = 25655448}}</ref> ==Theory== ==Evidence == The Canadian Consensus criteria for [[ME/CFS]] states that fluoxetine may be useful for [[depression]] in people with ME/CFS.<ref name="CCC" /> ==Risks and safety == Side effects include: *Nervousness and [[anxiety]] *Sweating *[[Headache]]s *[[Anorexia and eating disorders|Anorexia]] *[[Diarrhea]] *[[Dizziness]] *Dry mouth *[[Nausea]] *[[Somnolence|Drowsiness]] *[[Insomnia]] *Allergic reactions *[[Fatigue]] *[[Tremor]]s<ref name=drugscom>{{Cite web | url = https://www.drugs.com/fluoxetine.html|website =drugs.com | title = Fluoxetine |access-date = 2021-02-20}}</ref><ref name="CCC">{{Cite journal | last1 = Carruthers | first1 = Bruce M. | authorlink1 = Bruce Carruthers | last2 = Jain | first2 = Anil Kumar | authorlink2 = Anil Kumar Jain | last3 = De Meirleir | first3 = Kenny L. | authorlink3 = Kenny De Meirleir | last4 = Peterson | first4 = Daniel L. | authorlink4 = Daniel Peterson | last5 = Klimas | first5 = Nancy G. | authorlink5 = Nancy Klimas | last6 = Lerner | first6 = A. Martin | authorlink6 = Martin Lerner | last7 = Bested | first7 = Alison C. | author-link8 = Alison Bested | last8 = Flor-Henry | first8 = Pierre | author-link8 = Pierre Flor-Henry | last9 = Joshi | first9 = Pradip | author-link9 = Pradip Joshi | last10 = Powles | first10 = AC Peter | authorlink10 = A C Peter Powles | last11 = Sherkey | first11 = Jeffrey A. | authorlink11 = Jeffrey Sherkey | last12 = van de Sande | first12 = Marjorie I. | authorlink12 = Marjorie van de Sande| title = Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols| journal = Journal of Chronic Fatigue Syndrome | volume = 11 |issue = 2 | pages = 7-115 | date = 2003 | pmid = | doi = 10.1300/J092v11n01_02 |url = http://www.investinme.org/Documents/PDFdocuments/CanadianDefinitionME-CFS.pdf}}</ref> ==Costs and availability== Available on perscription only, in the form of a capsule or liquid. Widely available.<ref name=drugscom /> ==See also== *[[Depression]] *[[Anxiety]] ==Learn more== *[https://www.drugs.com/fluoxetine.html Fluoxetine] - drugs.com ==References== {{Reflist}} [[Category:Potential treatments]] [[Category:Antidepressants]] [[Category:Selective serotonin reuptake inhibitors]]
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