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Lillebeth Larun
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{{NeedsImage}} '''Lillebeth Larun''' is a researcher and health reviewer in [[Norway]] with an interest in [[chronic fatigue syndrome]].<ref name="niph">{{Cite web|url=http://www.fhi.no/en/about/about-niph/departments-and-centres/reviews-and-health-technology-assessments/lillebeth-larun/ | title = Lillebeth Larun | last = Norwegian Institute of Public Health|first = | authorlink = Norwegian Institute of Public Health | date = |website=[[Norwegian Institute of Public Health]]|language=en|archive-url=|archive-date=|url-status=|access-date=2019-03-30}}</ref> Larun is affliated with the [[Norwegian Institute of Public Health]] and author of [[Cochrane |Cochrane Collaboration]] reviews for [[Graded exercise therapy |exercise therapy]] in patients with CFS.<ref name="Cochrane2008" /> ==Talks and interviews== ==Notable studies == * 2008, [http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD001027.pub2/abstract Cognitive behaviour therapy for chronic fatigue syndrome in adults]<ref name="Cochrane2008">{{Cite journal | last = Price | first = Jonathan R. | authorlink = Jonathan Price | last2 = Mitchell | first2 = Edward | authorlink2 = Edward Mitchell | last3 = Tidy | first3 = Elizabeth | authorlink3 = Elizabeth Tidy | last4 = Hunot | first4 = Vivien | authorlink4 = Vivien Hunot | date = 2008 | title = Cognitive behaviour therapy for chronic fatigue syndrome in adults|url=https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD001027.pub2/abstract|journal=[[Cochrane |Cochrane Database of Systematic Reviews]]|language=en|volume=|issue=3| pages = CD001027|doi=10.1002/14651858.CD001027.pub2|issn=1465-1858|quote=|via=}}</ref> * '''Withdrawn:''' 2014, [http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD011040/abstract Exercise therapy for chronic fatigue syndrome (individual patient data)]<ref name="Cochrane2014">{{Cite journal | last = Larun | first = Lillebeth | authorlink = Lillebeth Larun | last2 = Odgaard‐Jensen | first2 = Jan | authorlink2 = Jan Odgaard‐Jensen | last3 = Brurberg | first3 = Kjetil G. | authorlink3 = Kjetil Brurberg | last4 = Chalder | first4 = Trudie | authorlink4 = Trudie Chalder | last5 = Dybwad | first5 = Marianne | authorlink5 = Marianne Dybwad | last6 = Moss‐Morris | first6 = Rona E. | authorlink6= Rona Moss-Morris|last7 = Sharpe | first7 = Michael | authorlink7 = Michael Sharpe | last8 = Wallman | first8 = Karen | authorlink8 = Karen Wallman | first9 = Alison | last9 = Wearden | authorlink9 = Alison Wearden | last10 = White | first10 = Peter | authorlink10 = Peter White | last11 = Glasziou | first11 = Paul P | authorlink11 = Paul Glasziou | date = 2014 | title=Exercise therapy for chronic fatigue syndrome (individual patient data)|url=https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD011040/abstract|journal=Cochrane Database of Systematic Reviews|language=en|volume=|issue=4|pages = CD011040 |doi=10.1002/14651858.CD011040|issn=1465-1858|pmc = PMC6494520 | quote=|via=}}</ref> :More recent version published in 2018 but also withdrawn *2016, [http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD003200.pub5/full Exercise therapy for chronic fatigue syndrome]<ref name="Cochrane2016">{{Cite journal | last = Larun | first = Lillebeth | authorlink = Lillebeth Larun | last2 = Brurberg | first2 = Kjetil G. | authorlink2 = Kjetil Brurberg | last3 = Odgaard‐Jensen | first3 = Jan | authorlink3 = Jan Odgaard-Jensen | last4 = Price | first4 = Jonathan R. | authorlink4 = Jonathan Price | date = 2016 | title=Exercise therapy for chronic fatigue syndrome|url=https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD003200.pub4/abstract|journal=Cochrane Database of Systematic Reviews|language=en|issue=2|doi=10.1002/14651858.CD003200.pub4|issn=1465-1858|pages = CD003200|quote=|via=|volume=}}</ref> :Most recent version is from 2019 * 2017, [https://www.cochrane.org/CD003200/DEPRESSN_exercise-treatment-patients-chronic-fatigue-syndrome Exercise as treatment for patients with chronic fatigue syndrome]<ref name="Cochrane2017">{{Cite journal | last = Larun | first = Lillebeth | authorlink = Lillebeth Larun | last2 = Brurberg | first2 = Kjetil G. | authorlink2 = Kjetil Brurberg | last3 = Odgaard-Jensen | first3 = Jan | authorlink3 = Jan Odgaard-Jensen | last4 = Price | first4 = Jonathan R | authorlink4 = Jonathan Price | date = 2017-04-25 | title = Exercise therapy for chronic fatigue syndrome|url=https://www.cochrane.org/CD003200/DEPRESSN_exercise-treatment-patients-chronic-fatigue-syndrome|journal=Cochrane Database of Systematic Reviews|volume=4|issue=4|pages = CD003200|language=en|doi=10.1002/14651858.CD003200.pub7|issn=1465-1858|quote=|via=}}</ref> *2018, '''Withdrawn:''' Exercise therapy for chronic fatigue syndrome (individual patient data)<ref name="Cochrane2018">{{Cite journal | last = Larun | first = Lillebeth | authorlink = Lillebeth Larun | last2 = Odgaard-Jensen | first2 = Jan | authorlink2 = Jan Odgaard-Jensen | last3 = Brurberg | first3 =Kjetil G. | authorlink3 = Kjetil Brurberg | last4 = Price | first4 = Jonathan R | authorlink4 = Jonathan Price | date = 2018-12-07 | title = Exercise therapy for chronic fatigue syndrome| journal=Cochrane Database of Systematic Reviews | url = https://www.cochranelibrary.com/content?templateType=full&urlTitle=/cdsr/doi/10.1002/14651858.CD011040.pub2&doi=10.1002/14651858.CD011040.pub2&type=cdsr&contentLanguage= |volume = 12 |issue=|pages = CD011040CD011040|language=en|doi=10.1002/14651858.CD011040.pub2 | pmc = PMC6517214|issn=1465-1858|quote=|via=}}</ref> * 2019, [https://doi.org/10.1002/14651858.CD003200.pub8 Exercise therapy for chronic fatigue syndrome] ==PhD thesis on Chronic Fatigue Syndrome== * 2011, Kronisk utmattelsessyndrom. Kunnskap, aktivitet og utfordringer.<ref name="LillebethPhD">{{Citation |last = Larun | first = Lillebeth | title = Kronisk utmattelsessyndrom. Kunnskap, aktivitet og utfordringer | authorlink = Lillebeth Larun |url=http://bora.uib.no/bitstream/handle/1956/5105/Dr.thesis_Lillebeth%20Larun.pdf | date = Sep 2011|quote=|via=|url-status=dead}}</ref> :Lillebeth Larun's theseis included three prior publications in support of the thesis, one of which used the [[PACE trial]] as a reference on support of her conclusion about exercise: ** 2001 Treningsbehandling ved knonisk utmattelsessyndrom. ** 2007 Identity and coping experiences in Chronic Fatigue Syndrome: A synthesis of qualitative studies.<ref>{{Cite journal | last = Larun | first = Lillebeth | authorlink = Lillebeth Larun | last2 = Malterud | first2 = Kirsti | authorlink2 = Kirsti Malterud | date = Dec 2007 | title = Identity and coping experiences in Chronic Fatigue Syndrome: a synthesis of qualitative studies|url=https://www.ncbi.nlm.nih.gov/pubmed/17698311|journal=Patient Education and Counseling|volume=69|issue=1-3|pages=20–28|doi=10.1016/j.pec.2007.06.008|issn=0738-3991|pmid=17698311|quote=|via=}}</ref> [https://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.572.1860&rep=rep1&type=pdf  2011 (Full text)] * 2011 Finding the right balance of physical activity. A focus group study about experiences among patients with chronic fatigue syndrome.<ref name="Larun2011">{{Cite journal | last = Larun | first = Lillebeth | authorlink = Lillebeth Larun | last2 = Malterud | first2 = Kirsti | authorlink2 = Kirsti Malterud | date = May 2011 | title = Finding the right balance of physical activity: a focus group study about experiences among patients with chronic fatigue syndrome|url=https://www.ncbi.nlm.nih.gov/pubmed/20580520|journal=Patient Education and Counseling|volume=83|issue=2|pages=222–226|doi=10.1016/j.pec.2010.05.027|issn=1873-5134|pmid=20580520|quote=|via=}}</ref> [[pubmed:20580520|(Abstract)]] ==Exercise therapy == Larun's PhD involved a number of aspects of research into [[chronic fatigue syndrome]], mostly in regard to the effects of [[exercise]]; she concluded chronic fatigue syndrome patients found exercise both enjoyable and beneficial, provided that it was guided by them and flexible.<ref name="LillebethPhD" /><ref name="Larun2011" /> In addition, she found no adverse effects, although this study relied on only a small number of patients, with either mild or moderate symptoms.<ref name="Larun2011" /> ==Cochrane review controversy == Lillebeth Larun was lead author for the [[Cochrane |Cochrane Collaboration]] review of [[Graded exercise therapy |exercise therapy]] for chronic fatigue syndrome, which has faced extensive calls for retraction from both scientists and patients, particularly after the publication of the [[PACE trial]] data that the influenced the conclusions. In addition to scientific complaints made by professionals including Professor [[James Coyne]],<ref>{{Cite web|url=https://jcoynester.wordpress.com/2016/04/23/probing-an-untrustworthy-cochrane-review-of-exercise-for-chronic-fatigue-syndrome/ | title = Probing an untrustworthy Cochrane review of exercise for "chronic fatigue syndrome"|last = Coyne | first = James | author-link = James Coyne | date = 2016-04-23|work=Quick Thoughts blog|access-date=2018-10-17|archive-url=|archive-date=|url-status=|language=en-US}}</ref> and by [[Robert Courtney]], a patient with [[ME/CFS]] submitted a number of queries followed by a complaint containing a scientific critique of Larun et al's review,<ref name="Courtney2016">{{Cite web |url = https://www.dropbox.com/s/uhy95caezsmcue7/Robert%20Courtney%20Cochrane%20complaint(1).zip?dl=0&file_subpath=%2F4+Cochrane+Review+-+Exercise+++++++++++++++++++++++++++therapy+for+CFS+-+Primary++++outcome++switching.pdf | title =Concerns regarding the use of unplanned primary outcomes in the Cochrane review | authorlink = Robert Courtney | last = Courtney | first = Robert | date = 2016}}</ref ><ref name ="Courtney2018">{{Cite web |url=https://www.dropbox.com/s/uhy95caezsmcue7/Robert%20Courtney%20Cochrane%20complaint(1).zip?dl=0&file_subpath=%2FRobert+Courtney+Cochrane+complaint.pdf | title =This is a formal complaint with respect to the current version of "Exercise therapy for chronic fatigue syndrome" by L. Larun et al. (Cochrane Database Syste Rev. 2017; CD003200.)|last = Courtney | first = Robert | authorlink = Robert Courtney}}</ref > focusing on how the methodology did not meet the Cochrane strict requirements.<br> A further controversy was the Cochrane Collaboration's decision to allocate the review to Cochrane's ''Common Mental Disorders Group'', although it also appears in the [[:Category:Neurological diseases and disorders |neurological]] category.<ref name="CochraneCFS">{{Cite web|url=https://www.cochrane.org/search/site?f%255B0%255D=im_field_terms_cochrane_library%253A51013 | title = Search & Browse|language=en|access-date=2018-10-17}}</ref> ==Online presence== *Twitter *Facebook *Website/Blog *YouTube ==See also== *[[Cochrane Collaboration]] *[[Graded exercise therapy]] *[[PACE trial]] *[[Intimidation and bullying of PACE trial critics]] *[[Biopsychosocial model]] ==Learn more== *Wikipedia *[https://community.cochrane.org/news/cochrane-and-conflict-interest Cochrane and conflict of interest]<ref>{{Cite web|url=https://community.cochrane.org/news/cochrane-and-conflict-interest | title = Cochrane and conflict of interest|website=community.cochrane.org|language=en|access-date=2018-10-17}}</ref> ==References== {{Reflist}} [[Category:Researchers]] [[Category:Psychological paradigm proponents]] [[Category:PACE trial proponents]] [[Category:Norway researchers]]
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