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Purinergic P2X 4 receptor
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{{stub}} '''Purinergic 2X 4 receptor''' or '''purinergic receptor P2 X, ligand-gated ion channel 4''' or '''P2XR4''' or '''P2X4''' or '''P2RX4'''.<ref name="genecards">{{Cite web|access-date=2022-04-07 | url=https://www.genecards.org/cgi-bin/carddisp.pl?gene=P2RX4 | title = P2RX4 Protein {{!}} P2RX4 Antibody |website=Gene cards}}</ref> ==Function== ==ME/CFS== ==Notable studies == *2016, Gene expression factor analysis to differentiate pathways linked to fibromyalgia, chronic fatigue syndrome, and depression in a diverse patient sample<ref name="Iacob2016">{{Cite journal | title = Gene expression factor analysis to differentiate pathways linked to fibromyalgia, chronic fatigue syndrome, and depression in a diverse patient sample | date = Jan 2016|url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684820/|journal=Arthritis care & research|volume=68|issue=1|pages=132β140 | last = Iacob | first = Eli | author-link = | last2 = Light | first2 = Alan R. | authorlink2 = Alan Light | last3 = Donaldson | first3 = Gary W. | authorlink3 = | last4 = Okifuji | first4 = Akiko | authorlink4 = | last5 = Hughen | first5 = Ronald W. | authorlink5 = | last6 = White | first6 = Andrea T. | authorlink6 = Andrea White | last7 = Light | first7 = Kathleen C. | authorlink7 = Kathleen Light|doi=10.1002/acr.22639|pmc=4684820|pmid=26097208|access-date=|issn=2151-464X|quote=|via=}}</ref> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684820/ (Full text)] *2012, Genetics and Gene Expression Involving Stress and Distress Pathways in Fibromyalgia with and without Comorbid Chronic Fatigue Syndrome<ref name="Light2012Stress">{{Cite journal | last1 = Light | first1 = KC | authorlink = Kathleen Light | last2 = White | first2 = AT | authorlink2 = Andrea White | last3 = Tadler | first3 =S | last4 = Iacob | first4 = E| last5 = Light | first5 = Alan R | authorlink5 = Alan Light | url= https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200121/ | title = Genetics and Gene Expression Involving Stress and Distress Pathways in Fibromyalgia with and without Comorbid Chronic Fatigue Syndrome |journal=Pain Research and Treatment | date = 2012 | page = 427869 | pmc = PMC3200121 |doi= 10.1155/2012/427869}}</ref> [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200121/ (Full text)] *2012, Differences in metabolite-detecting, adrenergic, and immune gene expression after moderate exercise in patients with chronic fatigue syndrome, patients with [[multiple sclerosis]], and healthy controls<ref name="White2012">{{Cite journal | last1 = White | first1 = AT | authorlink1 = Andrea White | last2 = Light | first2 = AR | authorlink2 = Alan Light | last3 = Hughen | first3 = RW | authorlink3 = | last4 = Vanhaitsma | first4 = TA | authorlink4 = | last5 = Light | first5 = KC | authorlink5 = Kathleen Light| title = Differences in metabolite-detecting, adrenergic, and immune gene expression after moderate exercise in patients with chronic fatigue syndrome, patients with multiple sclerosis, and healthy controls| journal = Psychosomatic Medicine | volume = 74 | issue = 1 | page = 46-54 | date = 2012| pmid = | pmc = PMC3256093| url = https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256093/| doi = 10.1097/PSY.0b013e31824152ed}}</ref> [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256093/ (Full text)] *2012, Gene expression alterations at baseline and following moderate exercise in patients with Chronic Fatigue Syndrome and Fibromyalgia Syndrome<ref name="Light2012FM">{{Cite journal | last1 = Light | first1 = Alan R | authorlink1 = Alan Light | last2 = Bateman | first2 = Lucinda | authorlink2 = Lucinda Bateman | last3 = Jo | first3 = Daehyun | authorlink3 = Daehyun Jo | last4 = Hughen | first4 = Ronald W | authorlink4 = | last5 = Vanhaitsma | first5 = Timothy A | authorlink5 = | last6 = White | first6 = AT | authorlink6 = Andrea White | last7 = Light | first7 = Kathleen | authorlink7 = Kathleen Light| title = Gene expression alterations at baseline and following moderate exercise in patients with Chronic Fatigue Syndrome and Fibromyalgia Syndrome| journal = Journal of Internal Medicine | volume = 271 | issue = 1 | page = 64-81 | date = 2012| pmid = | pmc = PMC3175315 | doi = 10.1111/j.1365-2796.2011.02405.x | url = https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175315/ }}</ref> [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175315/ (Full Text)] ==See also == *[[Transient receptor potential vanilloid receptor 1]] *[[Purinergic P2X 5 receptor]] *[[Acid sensing ion channel 3]] *[[Post-exertional malaise]] *[[Genetics of chronic fatigue syndrome]] ==Learn more == *[https://www.genecards.org/cgi-bin/carddisp.pl?gene=P2RX4 P2RX4 Protein {{!}} P2RX4 Antibody] - Gene card ==References == {{Reflist}} [[Category:Genes]] [[Category:Biochemistry and cell biology]] [[Category:Channelopathy]] [[Category:Energy system]] [[Category:Immunology]] [[Category:Proteins]] [[Category:Antibodies]]
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