Pentadecapeptide BPC 157
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Pentadecapeptide BPC 157, a fragment of gastric juice peptide BPC,[1] is an experimental compound used in research for its potential applications in wound healing, collagen repair and angiogenesis.[2]
BPC 157 improved wound healing in rats with muscle crush injury and contusions, and quadricep transection,[3][4] even in the presence of corticosteroids (which impair wound healing).[4] It has also demonstrated efficacy in experimental ulcer models[5] and models of traumatic nerve injury.[6]
References
- ↑ Sikiric, Predrag; Seiwerth, Sven; Grabarevic, Zeljko; Petek, Marijan; Rucman, Rudolf; Turkovic, Branko; Rotkvic, Ivo; Jagic, Vjekoslav; Duvnjak, Marko (January 1, 1994). "The beneficial effect of BPC 157, a 15 amino acid peptide BPC fragment, on gastric and duodenal lesions induced by restraint stress, cysteamine and 96% ethanol in rats. A comparative study with H2 receptor antagonists, dopamine promotors and gut peptides". Life Sciences. 54 (5): PL63–PL68. doi:10.1016/0024-3205(94)00796-9. ISSN 0024-3205.
- ↑ Seiwerth, Sven; Brcic, Luka; Batelja Vuletic, Lovorka; Kolenc, Danijela; Aralica, Gorana; Misic, Marija; Zenko, Anita; Drmic, Domagoj; Rucman, Rudolf (2014). "BPC 157 and Blood Vessels". www.ingentaconnect.com. Retrieved June 24, 2019.
- ↑ Staresinic, Mario; Petrovic, Igor; Novinscak, Tomislav; Jukic, Ivana; Pevec, Damira; Suknaic, Slaven; Kokic, Neven; Batelja, Lovorka; Brcic, Luka (2006). "Effective therapy of transected quadriceps muscle in rat: Gastric pentadecapeptide BPC 157". Journal of Orthopaedic Research. 24 (5): 1109–1117. doi:10.1002/jor.20089. ISSN 1554-527X.
- ↑ 4.0 4.1 Staresinic, Mario; Petrovic, Igor; Novinscak, Tomislav; Jukic, Ivana; Pevec, Damira; Suknaic, Slaven; Kokic, Neven; Batelja, Lovorka; Brcic, Luka (2006). "Effective therapy of transected quadriceps muscle in rat: Gastric pentadecapeptide BPC 157". Journal of Orthopaedic Research. 24 (5): 1109–1117. doi:10.1002/jor.20089. ISSN 1554-527X.
- ↑ Sikiric, Predrag; Seiwerth, Sven; Grabarevic, Zeljko; Petek, Marijan; Rucman, Rudolf; Turkovic, Branko; Rotkvic, Ivo; Jagic, Vjekoslav; Duvnjak, Marko (January 1, 1994). "The beneficial effect of BPC 157, a 15 amino acid peptide BPC fragment, on gastric and duodenal lesions induced by restraint stress, cysteamine and 96% ethanol in rats. A comparative study with H2 receptor antagonists, dopamine promotors and gut peptides". Life Sciences. 54 (5): PL63–PL68. doi:10.1016/0024-3205(94)00796-9. ISSN 0024-3205.
- ↑ Gjurasin, Miroslav; Miklic, Pavle; Zupancic, Bozidar; Perovic, Darko; Zarkovic, Kamelija; Brcic, Luka; Kolenc, Danijela; Radic, Bozo; Seiwerth, Sven (February 25, 2010). "Peptide therapy with pentadecapeptide BPC 157 in traumatic nerve injury". Regulatory Peptides. 160 (1): 33–41. doi:10.1016/j.regpep.2009.11.005. ISSN 0167-0115.
