Glossary

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A glossary of key ME/CFS-related terms.

A

accuracy
Accurate
accurate





Accuracy
Accuracy - The "closeness of an observation to the true clinical state". With respect to diagnostic tests, "accuracy" means how specific and sensitive the test is.
  • Accuracy - The "closeness of an observation to the true clinical state".[1] With respect to diagnostic tests, "accuracy" means how specific and sensitive the test is.[2]


Adverse reactions
adverse reaction
adverse reactions
side effect
side effects
Side effect
Side effects



Adverse reaction
Adverse reaction - Any unintended or unwanted response to the treatment under investigation in a clinical trial.
  • Adverse reaction - Any unintended or unwanted response to the treatment under investigation in a clinical trial.[3]


APA
American Psychiatric Assoc
American Psychiatric Assoc





American Psychiatric Association
American Psychiatric Association - the main professional organization of psychiatrists and trainee psychiatrists in the United States, and the largest psychiatric organization in the world
  • American Psychiatric Association - the main professional organization of psychiatrists and trainee psychiatrists in the United States, and the largest psychiatric organization in the world[4]


antibody
Antibodies
antibodies
Immunoglobulin
immunoglobulin
Immunoglobulins
immunoglobulins



Antibody
Antibody - Antibodies or immunoglobulin refers to any of a large number of specific proteins produced by B cells that act against an antigen in an immune response.
  • Antibody - Antibodies or immunoglobulin refers to any of a large number of specific proteins produced by B cells that act against an antigen in an immune response.

B

B cells
B-cell
B lymphocyte
B lymphocytes
B-cells




B cell
B cell - B lymphocyte, or a type of white blood cell, which is involved in the immune response by secreting antibodies to ward off infections. In mammals, they are mostly matured in the bone marrow.
  • B cell - B lymphocyte, or a type of white blood cell, which is involved in the immune response by secreting antibodies to ward off infections. In mammals, they are mostly matured in the bone marrow.[5]


bias
Biased
biased





Bias
Bias - Bias in research is "a systematic deviation of an observation from the true clinical state".
  • Bias - Bias in research is "a systematic deviation of an observation from the true clinical state".[1]


BPS model
BPS Model
biopsychosocial model
biopsychosocial
Biopsychosocial
Biopsychosocial Model



BPS
Biopsychosocial model
Biopsychosocial model (BPS) - A school of thought, usually based in psychology, which claims illness and disease to be the result of the intermingling of biological, psychological and social causes. (Learn more: en.wikipedia.org)
  • Biopsychosocial model (BPS) - A school of thought, usually based in psychology, which claims illness and disease to be the result of the intermingling of biological, psychological and social causes. (Learn more: en.wikipedia.org)



bradycardia






Bradycardia
Bradycardia - A slowness of the heartbeat, so that the pulse rate is less than 60 per minute in an adult.
  • Bradycardia - A slowness of the heartbeat, so that the pulse rate is less than 60 per minute in an adult.[6]

C

Canadian Consensus Criteria





CCC
Canadian consensus criteria
Canadian consensus criteria (CCC) - A set of diagnostic criteria used to diagnose ME/CFS, developed by a group of practicing ME/CFS clinicians in 2003. The CCC is often considered to be the most complex criteria, but possibly the most accurate, with the lowest number of patients meeting the criteria. Led to the development of the International Consensus Criteria (ICC) in 2011.
  • Canadian consensus criteria (CCC) - A set of diagnostic criteria used to diagnose ME/CFS, developed by a group of practicing ME/CFS clinicians in 2003. The CCC is often considered to be the most complex criteria, but possibly the most accurate, with the lowest number of patients meeting the criteria. Led to the development of the International Consensus Criteria (ICC) in 2011.[7]




cell membrane
Cell membranes
cell membranes
Plasma membrane
plasma membrane
Plasma membranes
plasma membranes



Cell membrane
Cell membrane - A very thin membrane, composed of lipids and protein, that surrounds the cytoplasm of a cell and controls the passage of substances into and out of the cell.
  • Cell membrane - A very thin membrane, composed of lipids and protein, that surrounds the cytoplasm of a cell and controls the passage of substances into and out of the cell.[8]


Cerebellum
cerebellar
Cerebellar





cerebellum
cerebellum - the part of the brain at the back of the skull in vertebrates. Its function is the coordination of muscles and the maintenance of bodily equilibrium
  • cerebellum - the part of the brain at the back of the skull in vertebrates. Its function is the coordination of muscles and the maintenance of bodily equilibrium[9]


Chronic disease
Chronic Disease
chronic diseases
Chronic diseases
Chronic Diseases




chronic disease
chronic disease - a disease or condition that usually lasts for 3 months or longer and may get worse over time
  • chronic disease - a disease or condition that usually lasts for 3 months or longer and may get worse over time[10]



chronic fatigue





CF
Chronic fatigue
Chronic fatigue (CF) - Persistent and abnormal fatigue is a symptom, not an illness. It may be caused by depression, multiple sclerosis, fibromyalgia, chronic fatigue syndrome or many other illnesses. The term "chronic fatigue" should never be confused with the disease chronic fatigue syndrome.
  • Chronic fatigue (CF) - Persistent and abnormal fatigue is a symptom, not an illness. It may be caused by depression, multiple sclerosis, fibromyalgia, chronic fatigue syndrome or many other illnesses. The term "chronic fatigue" should never be confused with the disease chronic fatigue syndrome.[11]
  • Chronic Fatigue Syndrome (CFS) - may be more likely to refer to those diagnosed using the Fukuda Criteria or the Oxford definition. Commonly used in the United States as the name of the disease. Viewed by some patients as dismissive and derogatory.


Chronic Fatigue Syndrome Advisory Committee
chronic fatigue syndrome advisory committee





CFSAC
Chronic fatigue syndrome advisory committee
Chronic fatigue syndrome advisory committee (CFSAC) - (sometimes pronounced SIF-SACK) A US government advisory council that met twice per year, covering current topics related to Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Meetings usually lasted for two days and the results were presented to the Secretary of Health and Human Services (HHS). After 15 years, on September 5, 2018, CFSAC's charter was not renewed by the Department of HHS, effectively dissolving the committee without notice or warning.
  • Chronic fatigue syndrome advisory committee (CFSAC) - (sometimes pronounced SIF-SACK) A US government advisory council that met twice per year, covering current topics related to Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Meetings usually lasted for two days and the results were presented to the Secretary of Health and Human Services (HHS). After 15 years, on September 5, 2018, CFSAC's charter was not renewed by the Department of HHS, effectively dissolving the committee without notice or warning.[12]


clivi
Clivus
Clivi





clivus
clivus - the smooth sloping surface on the upper posterior part of the body of the sphenoid bone supporting the pons and the basilar artery
  • clivus - the smooth sloping surface on the upper posterior part of the body of the sphenoid bone supporting the pons and the basilar artery[13]


cofactors
Cofactor
Cofactors





cofactor
cofactor - a substance that acts with another substance to bring about certain effects
  • cofactor - a substance that acts with another substance to bring about certain effects[14]


cognition
Cognitive
cognitive
Cognitions
cognitions




Cognition
Cognition - Thought processes, including attention, reasoning, and memory.
  • Cognition - Thought processes, including attention, reasoning, and memory.


Cognitive Behavioral Therapy
cognitive behavioral therapy
Cognitive behavioural therapy
Cognitive Behavioural Therapy
cognitive behavioural therapy



CBT
Cognitive behavioral therapy
Cognitive behavioral therapy (CBT) - A type of psychotherapy geared toward modifying alleged unhealthy thinking, behaviors or illness beliefs. One of the treatment arms used in the controversial PACE trial.


conversion disorder
Conversion Disorder
conversion disorders
Conversion Disorders
Conversion disorders




Conversion disorder
Conversion disorder - A psychiatric term to describe an alleged condition whereby a person's thoughts somehow cause physical symptoms. The actual existence of such a condition is highly controversial, due to a lack of scientific evidence. It is related to other psychiatric terms, such as "neurasthenia" and "hysteria". A more modern term is "Somatic Symptom Disorder".
  • Conversion disorder - A psychiatric term to describe an alleged condition whereby a person's thoughts somehow cause physical symptoms. The actual existence of such a condition is highly controversial, due to a lack of scientific evidence. It is related to other psychiatric terms, such as "neurasthenia" and "hysteria". A more modern term is "Somatic Symptom Disorder".[15]


D

E

endogenous






Endogenous
Endogenous - Growing or originating from within an organism.
  • Endogenous - Growing or originating from within an organism.[16]
  • enterovirus - a genus of RNA viruses which typically enter the body through the gastrointestinal tract and can sometimes spread to the central nervous system or other parts of the body. Enteroviruses include those which cause polio and coxsackievirus.


Epigenome
epigenomes
Epigenomes





epigenome
epigenome - all of the chemical compounds that are not part of the DNA sequence, but are on or attached to DNA as a way to regulate genes activity
  • epigenome - all of the chemical compounds that are not part of the DNA sequence, but are on or attached to DNA as a way to regulate genes activity[17]


Enzyme
enzymes
Enzymes





enzyme
enzyme - a substance produced by a living organism which acts as a catalyst to bring about a specific biochemical reaction.
  • enzyme - a substance produced by a living organism which acts as a catalyst to bring about a specific biochemical reaction.[18]

F

Foramen magnum
Foramen Magnum





foramen magnum
foramen magnum - the large opening in the skull through which the spinal cord passes to merge with the lower brain
  • foramen magnum - the large opening in the skull through which the spinal cord passes to merge with the lower brain[19]







Fukuda criteria
Fukuda criteria - The most commonly used diagnostic criteria for chronic fatigue syndrome, created by the United States Centers for Disease Control (CDC).
  • Fukuda criteria - The most commonly used diagnostic criteria for chronic fatigue syndrome, created by the United States Centers for Disease Control (CDC).[20]

G

Genome
genomes
Genomes





genome
genome - an organism’s complete set of DNA, including all of its genes
  • genome - an organism’s complete set of DNA, including all of its genes[21]



Graded Exercise Therapy
graded exercise therapy





GET
Graded exercise therapy
Graded exercise therapy (GET) - A gradual increase in exercise or activity, according to a pre-defined plan. Focuses on overcoming the patient's alleged unhelpful illness beliefs that exertion can exacerbate symptoms, rather than on reversing physical deconditioning. Considered controversial, and possibly harmful, in the treatment or management of ME. One of the treatment arms of the controversial PACE trial.
  • Graded exercise therapy (GET) - A gradual increase in exercise or activity, according to a pre-defined plan. Focuses on overcoming the patient's alleged unhelpful illness beliefs that exertion can exacerbate symptoms, rather than on reversing physical deconditioning. Considered controversial, and possibly harmful, in the treatment or management of ME. One of the treatment arms of the controversial PACE trial.[22]


Glutamate






glutamate
glutamate - a salt or ester of glutamic acid which functions as the principal excitatory neurotransmitter in brain
  • glutamate - a salt or ester of glutamic acid which functions as the principal excitatory neurotransmitter in brain[23][24]

H

  • HLA complex (human leukocyte antigen) - a gene complex responsible for encoding certain proteins which help the immune system to distinguish the body's own proteins from proteins which are made by foreign invaders like bacteria and viruses. See also "Dr Ron Davis’s big immune study is looking at HLA genes"


Hypoglycemia
hypoglycemic
Hypoglycemic
hypoglycemics
Hypoglycemics




hypoglycemia
hypoglycemia - abnormal decrease of sugar in the blood
  • hypoglycemia - abnormal decrease of sugar in the blood[25]


I

iatrogenesis
Iatrogenic
iatrogenic





Iatrogenesis
Iatrogenesis - Accidental harm caused by a doctor, by medical treatment, or by diagnostic procedures.
  • Iatrogenesis - Accidental harm caused by a doctor, by medical treatment, or by diagnostic procedures.[26]
  • ICD - International Classification of Diseases. A system of medical codes created by the World Health Organization (WHO) for diseases and other health related conditions for the purpose of international consistency. The 11th revision, or ICD-11, is due in 2018.


  • IOM - Institute of Medicine, (National Academy of Medicine (NAM) as of June 2015) is an American non-profit, non-governmental organization which provides expert advice on issues relating to biomedical science, medicine and health.


immunomodulatory
Immunomodulator
Immunomodulatory





immunomodulator
immunomodulator - a substance that affects the functioning of the immune system
  • immunomodulator - a substance that affects the functioning of the immune system[27]
  • Institute of Medicine report - or IOM Report, was published by the Institute of Medicine on February 10 2015. The report Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Redefining an Illness proposed the name Systemic Exertion Intolerance Disease (SEID). Among its key findings were that "This disease is characterized by profound fatigue, cognitive dysfunction, sleep abnormalities, autonomic manifestations, pain, and other symptoms that are made worse by exertion of any sort." — "Between 836,000 and 2.5 million Americans suffer from myalgic encephalomyelitis/chronic fatigue syndrome."
  • invisible illness - a chronic condition or illness, such as ME/CFS, which may not be apparent to others. Sufferers may look healthy, yet be in poor health. Symptoms of the illness may not be visible and can be misunderstood or go unnoticed by others. Also, patients may wind up secluded or homebound due to the illness and become "invisible".

J

K

L

M

  • magnetic levitation device - uses ferrofluid (a liquid which can become magnetized) in a glass capillary tube surrounded by magnets. This creates a density gradient and cells move to their respective densities within the tube. White blood cells in CFS patients have been discovered to be less dense than those of healthy controls, indicating the possible use of the device as an inexpensive diagnostic test. This technology is being developed by Ron Davis' team at Stanford University. See also OMF Funded Diagnostic Technology Development
  • mass spectrometer - a device which converts molecules to ions, or charged particles. It then uses magnetic and electric fields to sort the ions according to their mass (similar to weight) and charge, and measure their characteristics.








ME/CFS
ME/CFS - An acronym that combines myalgic encephalomyelitis with chronic fatigue syndrome. Sometimes they are combined because people have trouble distinguishing one from the other. Sometimes they are combined because people see them as synonyms of each other.
  • medically unexplained physical symptoms (MUPS) - technically the term means that there is no known medical cause or explanation for the patient's symptoms. However, MUS or MUPS are generally lumped into a psychosomatic, or psychologically caused category by those in the medical profession.
  • metabolic trap hypothesis - hypothesis proposed by Dr. Robert Phair. Based on preliminary data from the OMF-funded ME/CFS Severely Ill Patient Study (SIPS), which found several genes which may carry mutations in people with ME. These mutations may cause enzymes which process important metabolites to slow down and cause a metabolic trap, which could explain some symptoms in ME/CFS.
  • metabolite - a substance produced by, or involved in metabolism.
  • metabolomics - the study and analysis of the chemical processes of metabolites within cells, tissues or organisms.
  • microbiome - the collective of microscopic organisms (including bacteria, viruses and fungi) and their genetic material, which are present in a particular environment, particularly in the human body.
  • Millions Missing - a global campaign, first led by #MEAction in May 2016, which aims to gain awareness, community, education, research, funding and treatment equality for Myalgic Encephalomeyelitis. See also #MillionsMissing on Twitter.
  • mitochondria - organelles or subunits within a cell. Their primary role is to take in nutrients and produce energy for the cell in the form of ATP (adenosine triphosphate). This process requires oxygen and is called aerobic respiration.


myalgia






Myalgia
Myalgia - Muscle pain.


Myalgic Encephalomyelitis
myalgic encephalomyelitis
Myalgic encephalopathy
Myalgic Encephalopathy
myalgic encephalopathy
M.E.



ME
Myalgic encephalomyelitis
Myalgic encephalomyelitis (ME) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.
  • Myalgic encephalomyelitis (ME) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome.[29] A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.[30]






Myalgic encephalopathy
Myalgic encephalopathy - An alternate term that is sometimes used for myalgic encephalomyelitis, by people who believe the evidence for inflammation in ME is insufficient. This terminology reflects the belief that the "-itis" suffix implies inflammation.
  • Myalgic encephalopathy - An alternate term that is sometimes used for myalgic encephalomyelitis, by people who believe the evidence for inflammation in ME is insufficient. This terminology reflects the belief that the "-itis" suffix implies inflammation.

N

  • nanoneedle - a nanofabricated device (one nanometer = one millionth of a millimeter) which measures electrical impedance from a drop of blood. The electrical impedance increased in the blood cells of 10 ME/CFS patients when stressed with salt, but not in healthy controls. This device may be able to distinguish ME/CFS patients from healthy controls and is being developed by Ron Davis' team at Standford University. See also OMF Funded Diagnostic Technology Development


naturopathy
naturopathic
Naturopath
Naturopathy
Naturopathic




naturopath
naturopath - a system of treatment of disease that avoids drugs and surgery and emphasizes the use of natural agents (such as air, water, and herbs) and physical means (such as tissue manipulation and electrotherapy)
  • naturopath - a system of treatment of disease that avoids drugs and surgery and emphasizes the use of natural agents (such as air, water, and herbs) and physical means (such as tissue manipulation and electrotherapy)[31]


NICE Guidelines
NICE guideline
NICE Guideline





NICE guidelines
NICE guidelines - Clinical guidelines used in the UK.

O


Oxford U.
Oxford Uni
University of Oxford





Oxford University
Oxford University - a prestigious university located in Oxford, England renowned for its teaching and research in health and medicine
  • Oxford University - a prestigious university located in Oxford, England renowned for its teaching and research in health and medicine[33]

P

  • PACE trial - a controversial study which claims that CBT and GET are effective in treating CFS/ME. Its results and methodology are disputed by patients, scientists and peer-reviewed scientific literature.
  • pacing - the practice of staying within one's "energy envelope" by interspersing periods of activity with periods of rest. Patients may use pacing with a heart rate monitor as an objective measure of exertion.





pharyngitis






Pharyngitis
Pharyngitis - An irritation or swelling of the top part of the throat, at the back of the mouth, usually caused by an infection such as Streptococcus. The hallmark symptom is a sore throat without cough.
  • Pharyngitis - An irritation or swelling of the top part of the throat, at the back of the mouth, usually caused by an infection such as Streptococcus. The hallmark symptom is a sore throat without cough.[34][35]


Phase 3
Phase III
phase three
phase 3
phase III




Phase three
Phase three - Last phase of clinical trials before a drug can be approved for public use. Whereas Phase one assesses basic safety, and Phase two assesses basic efficacy, Phase three uses many trial participants to fully assess both safety and efficacy.
  • Phase three - Last phase of clinical trials before a drug can be approved for public use. Whereas Phase one assesses basic safety, and Phase two assesses basic efficacy, Phase three uses many trial participants to fully assess both safety and efficacy.[36]


post-exertional malaise
Post-exertional Malaise
Post exertional malaise
post exertional malaise
Post Exertional Malaise
Postexertional malaise
postexertional malaise
Postexertional Malaise


PEM
Post-exertional malaise
Post-exertional malaise (PEM) - A notable exacerbation of symptoms brought on by small physical or cognitive exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others.
  • Post-exertional malaise (PEM) - A notable exacerbation of symptoms brought on by small physical or cognitive exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others.


post-exertional neuroimmune exhaustion
Post-exertional Neuroimmune Exhaustion
Postexertional neuroimmune exhaustion
postexertional neuroimmune exhaustion
Postexertional Neuroimmune Exhaustion
Post exertional neuroimmune exhaustion
post exertional neuroimmune exhaustion
Post Exertional Neuroimmune Exhaustion


PENE
Post-exertional neuroimmune exhaustion
Post-exertional neuroimmune exhaustion (PENE) - An alternative term for post-exertional malaise (PEM), used by people who find that the word 'malaise' fails to capture the serious nature of the condition. Used in the Institute of Medicine (IOM) report.
  • Post-exertional neuroimmune exhaustion (PENE) - An alternative term for post-exertional malaise (PEM), used by people who find that the word 'malaise' fails to capture the serious nature of the condition. Used in the Institute of Medicine (IOM) report.[37]


postural orthostatic tachycardia syndrome
Postural Orthostatic Tachycardia Syndrome





POTS
Postural orthostatic tachycardia syndrome
Postural orthostatic tachycardia syndrome (POTS) - A form of orthostatic intolerance where the cardinal symptom is excessive tachycardia due to changing position (e.g. from lying down to sitting up).



PWME
PwME's
PwMEs
pwme




PwME
PwME - Acronym for a "Person with ME" (myalgic encephalomyelitis).
  • PwME - Acronym for a "Person with ME" (myalgic encephalomyelitis).

Q

R


randomized controlled trial
Randomized Controlled Trial
Randomized controlled trials
randomized controlled trials
Randomized Controlled Trials
Randomised controlled trial
randomised controlled trial
Randomised Controlled Trial


RCT
Randomized controlled trial
Randomized controlled trial (RCT) - A trial in which participants are randomly assigned to two groups, with one group receiving the treatment being studied and a control or comparison group receiving a sham treatment, placebo, or comparison treatment.
  • Randomized controlled trial (RCT) - A trial in which participants are randomly assigned to two groups, with one group receiving the treatment being studied and a control or comparison group receiving a sham treatment, placebo, or comparison treatment.[38]
  • RCT - See Randomized controlled trial.

S

  • Seahorse analyzer - an instrument which measures oxygen consumption rate and extracellular acidification rate in live cells, in real time, producing information regarding important cellular functions such as mitochondrial respiration and glycolysis.
  • SF-36 (Short Form (36) Health Survey) - a 36 item patient reported questionnaire, used to determine patient health status and quality of life.
single nucleotide polymorphism
Single Nucleotide Polymorphism
Single nucleotide polymorphisms
single nucleotide polymorphisms
Single Nucleotide Polymorphisms
Single nucleotide variant
single nucleotide variant
Single Nucleotide Variant
SNV
single nucleotide variants
SNP
Single nucleotide polymorphism
Single nucleotide polymorphism (SNP) - A single nucleotide polymorphism (SNP, pronounced "snip") is a potential genetic mutation that occurs in a single spot in the human genome; a difference in a single DNA building block. SNPs are often represented by an "rs" number, such as "rs53576".
  • somatic - relating to the physical body. In biology, all the cells of the body, except those which form egg or sperm. Easily confused with "somatoform" or "psychosomatic".
  • somatoform disorder - a mental health disorder in which a patient experiences symptoms which can not be explained by current medical knowledge. Symptoms are considered real, even though the cause is never found and is assumed to be psychological. Patients who disagree with the psychological diagnosis of somatoform disorder and the lack of further investigation into their symptoms are often met with skepticism or even disdain by the medical community.


Spoon Theory
spoon theory





Spoon theory
Spoon theory - An analogy which equates the amount of ability that someone with chronic illness has to complete daily tasks to a limited number of spoons.
  • Spoon theory - An analogy which equates the amount of ability that someone with chronic illness has to complete daily tasks to a limited number of spoons.[42]
  • spoonie - a person, usually with a chronic illness, with a limited amount of energy or health, or "spoons". See also Spoon Theory
stress fracture
Stress Fracture
Stress fractures
stress fractures
Stress Fractures




Stress fracture
Stress fracture - A tiny crack in a bone caused by repetitive forces such as running or by normal use of a bone that's weakened by a condition such as osteoporosis.
  • Stress fracture - A tiny crack in a bone caused by repetitive forces such as running or by normal use of a bone that's weakened by a condition such as osteoporosis.[43]


Serum
blood serum
Blood serum
Blood Serum




serum
serum - the clear yellowish fluid that remains from blood plasma after clotting factors have been removed by clot formation
  • serum - the clear yellowish fluid that remains from blood plasma after clotting factors have been removed by clot formation[44]


subluxations
Subluxation
Subluxations





subluxation
subluxation - partial dislocation (as of one of the bones in a joint)
  • subluxation - partial dislocation (as of one of the bones in a joint)[45]


systemic exertion intolerance disease
Systemic Exertion Intolerance Disease





SEID
Systemic exertion intolerance disease
Systemic exertion intolerance disease (SEID) - A term for ME/CFS that aims to avoid the stigma associated with the term "chronic fatigue syndrome", while emphasizing the defining characteristic of post-exertional malaise (PEM). SEID was defined as part of the diagnostic criteria put together by the Institute of Medicine (IOM) report of 10 February 2015.
  • Systemic exertion intolerance disease (SEID) - A term for ME/CFS that aims to avoid the stigma associated with the term "chronic fatigue syndrome", while emphasizing the defining characteristic of post-exertional malaise (PEM). SEID was defined as part of the diagnostic criteria put together by the Institute of Medicine (IOM) report of 10 February 2015.[46]

T


tachycardia






Tachycardia
Tachycardia - An unusually rapid heart beat. Can be caused by exercise or illness. A symptom of postural orthostatic tachycardia syndrome (POTS). (Learn more: www.heart.org)

U

V

virome
Human Virome
human virome




Virome
Virome - The human virome is the collection of all viruses that are found in or on humans
  • Virome - The human virome is the collection of all viruses that are found in or on humans[48]


VO2Max
VO2 Max
vO2 max
VO2 max
vO2 Max
vO2max
maximal oxygen consumption



VO2max
VO2max - the maximum amount of oxygen the body can utilize during a specified period of usually intense exercise
  • VO2max - the maximum amount of oxygen the body can utilize during a specified period of usually intense exercise[49]


W


World health organization





WHO
World Health Organization
World Health Organization (WHO) - "A specialized agency of the United Nations that is concerned with public health. It was established on 7 April 1948, and is headquartered in Geneva, Switzerland. The WHO is a member of the United Nations Development Group. Its predecessor, the Health Organization, was an agency of the League of Nations." The International Statistical Classification of Diseases and Related Health Problems (ICD) is maintained by WHO.
  • World Health Organization (WHO) - "A specialized agency of the United Nations that is concerned with public health. It was established on 7 April 1948, and is headquartered in Geneva, Switzerland. The WHO is a member of the United Nations Development Group. Its predecessor, the Health Organization, was an agency of the League of Nations."[50] The International Statistical Classification of Diseases and Related Health Problems (ICD) is maintained by WHO.[51]

X

Y

Z

References

  1. 1.0 1.1 Sackett, David; Haynes, R. Brian; Tugwell, Peter (1985). Clinical epidemiology : a basic science for clinical medicine (1st ed.). Boston: Little, Brown. p. 30. ISBN 0316765953. OCLC 11703862. 
  2. Zhu; Zeng; Wang. "Sensitivity, Specificity, Accuracy, Associated Confidence Interval and ROC Analysis with Practical SAS® Implementations" (PDF). Lex Jansen. Retrieved Nov 12, 2019. 
  3. "Glossary". Health Research Authority. Retrieved Oct 31, 2019. 
  4. https://www.psychiatry.org/
  5. "B lymphocyte". TheFreeDictionary.com. Retrieved Nov 12, 2019. 
  6. "Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition". thefreedictionary. 2003. Retrieved Apr 18, 2019. 
  7. Carruthers, Bruce (2003). "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols" (PDF). Invest in ME. Retrieved Nov 12, 2019. 
  8. "Cell membrane definition and meaning | Collins English Dictionary". www.collinsdictionary.com. Retrieved Oct 19, 2019. 
  9. "Definition of cerebellum". www.merriam-webster.com. Retrieved Dec 3, 2019. 
  10. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/chronic-disease
  11. Carruthers, Bruce M.; van de Sande, Marjorie I.; De Meirleir, Kenny L.; Klimas, Nancy G.; Broderick, Gordon; Mitchell, Terry; Staines, Donald; Powles, A. C. Peter; Speight, Nigel; Vallings, Rosamund; Bateman, Lucinda; Baumgarten-Austrheim, Barbara; Bell, David; Carlo-Stella, Nicoletta; Chia, John; Darragh, Austin; Jo, Daehyun; Lewis, Donald; Light, Alan; Marshall-Gradisnik, Sonya; Mena, Ismael; Mikovits, Judy; Miwa, Kunihisa; Murovska, Modra; Pall, Martin; Stevens, Staci (Aug 22, 2011). "Myalgic encephalomyelitis: International Consensus Criteria". Journal of Internal Medicine. 270 (4): 327–338. doi:10.1111/j.1365-2796.2011.02428.x. ISSN 0954-6820. PMC 3427890Freely accessible. PMID 21777306. 
  12. "HHS Secretary Kills CFSAC!". #MEAction. Sep 7, 2018. Retrieved Nov 12, 2019. 
  13. https://www.merriam-webster.com/medical/clivus
  14. https://www.merriam-webster.com/dictionary/cofactor
  15. "Bad News: DSM 5 Refuses to Correct Somatic Symptom Disorder". Psychology Today. Retrieved Nov 12, 2019. 
  16. "Endogenous | Definition of Endogenous by Lexico". Lexico Dictionaries | English. Retrieved Oct 31, 2019. 
  17. https://ghr.nlm.nih.gov/primer/howgeneswork/epigenome
  18. Oxford English Dictionary. 2019. 
  19. Collins Dictionary. 2019. 
  20. Fukuda, K.; Straus, S. E.; Hickie, I.; Sharpe, M. C.; Dobbins, J. G.; Komaroff, A. (Dec 15, 1994). "The chronic fatigue syndrome: a comprehensive approach to its definition and study. International Chronic Fatigue Syndrome Study Group" (PDF). Annals of Internal Medicine. American College of Physicians. 121 (12): 953–959. doi:10.7326/0003-4819-121-12-199412150-00009. ISSN 0003-4819. PMID 7978722. 
  21. https://ghr.nlm.nih.gov/primer/hgp/genome
  22. White, PD; Goldsmith, KA; Johnson, AL; Potts, L; Walwyn, R; DeCesare, JC; Baber, HL; Burgess, M; Clark, LV; Cox, DL; Bavinton, J; Angus, BJ; Murphy, G; Murphy, M; O'Dowd, H; Wilks, D; McCrone, P; Chalder, T; Sharpe, M; The PACE Trial Management Group (Mar 5, 2011). "Comparison of adaptive pacing therapy, cognitive behaviour therapy, graded exercise therapy, and specialist medical care for chronic fatigue syndrome (PACE): a randomised trial". The Lancet. 377 (9768): 823–836. doi:10.1016/S0140-6736(11)60096-2. PMID 21334061. 
  23. https://www.merriam-webster.com/dictionary/glutamate
  24. https://www.ncbi.nlm.nih.gov/pubmed/10736372
  25. https://www.merriam-webster.com/dictionary/hypoglycemia
  26. https://www.merriam-webster.com/dictionary/iatrogenic#medicalDictionary
  27. https://www.merriam-webster.com/dictionary/immunomodulator
  28. "myalgia". The Free Dictionary. 
  29. Carruthers, BM; van de Sande, MI; De Meirleir, KL; Klimas, NG; Broderick, G; Mitchell, T; Staines, D; Powles, ACP; Speight, N; Vallings, R; Bateman, L; Bell, DS; Carlo-Stella, N; Chia, J; Darragh, A; Gerken, A; Jo, D; Lewis, DP; Light, AR; Light, KC; Marshall-Gradisnik, S; McLaren-Howard, J; Mena, I; Miwa, K; Murovska, M; Stevens, SR (2012), Myalgic encephalomyelitis: Adult & Paediatric: International Consensus Primer for Medical Practitioners (PDF), ISBN 978-0-9739335-3-6 
  30. World Health Organization (2016). "International Classification of Diseases" (10th ed.). 
  31. https://www.merriam-webster.com/dictionary/naturopathy
  32. "NICE | The National Institute for Health and Care Excellence". NICE. Retrieved Apr 15, 2019. 
  33. http://www.ox.ac.uk/
  34. https://www.merriam-webster.com/dictionary/pharyngitis#medicalDictionary
  35. https://bestpractice.bmj.com/topics/en-gb/5
  36. "Home - ClinicalTrials.gov". clinicaltrials.gov. Retrieved Apr 15, 2019. 
  37. Read "Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Redefining an Illness" at NAP.edu. 
  38. "Randomized Controlled Trial - Study Design 101". himmelfarb.gwu.edu. Retrieved Nov 12, 2019. 
  39. Genetics Home Reference. "What are single nucleotide polymorphisms (SNPs)?". Genetics Home Reference. Retrieved Oct 3, 2019. 
  40. https://www.merriam-webster.com/dictionary/SNP
  41. "rs53576 - SNPedia". www.snpedia.com. Retrieved Oct 6, 2019. 
  42. "The Spoon Theory written by Christine Miserandino". But You Dont Look Sick? support for those with invisible illness or chronic illness. Apr 25, 2013. Retrieved Nov 12, 2019. 
  43. "Stress fractures - Symptoms and causes". Mayo Clinic. Retrieved Oct 10, 2019. 
  44. https://www.merriam-webster.com/dictionary/blood%20serum
  45. https://www.merriam-webster.com/dictionary/subluxation
  46. Institute of Medicine; Committee on the Diagnostic Criteria for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (Feb 10, 2015), Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Redefining an Illness, Washington, DC: The National Academies Press, doi:10.17226/19012 
  47. https://www.merriam-webster.com/dictionary/tachycardia
  48. "virome". Retrieved Nov 21, 2019. 
  49. "VO2max". Retrieved Nov 21, 2019. 
  50. https://en.wikipedia.org/wiki/World_Health_Organization World Health Organization
  51. World Health Organization. "Home". www.who.int. Retrieved Apr 15, 2019. 

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