Coenzyme Q10
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Coenzyme Q10 (CoQ10) or ubiquinone is found in the mitochondria and as a component of the electron transport chain plays an important role in aerobic respiration.
Evidence[edit | edit source]
Plasma CoQ10 was found to be significantly lower in ME/CFS patients than in normal controls and correlated with symptom severity.[1] A literature review found that CoQ10 was marginally deficient in people with chronic fatigue syndrome.[2]
Ubiquinol-10 supplementation can improve autonomic nervous function and cognitive function in chronic fatigue syndrome.[3]
Notable studies[edit | edit source]
- 2000, Nutritional Strategies for Treating Chronic Fatigue Syndrome[2] (Full text)
- 2009, Coenzyme Q10 deficiency in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is related to fatigue, autonomic and neurocognitive symptoms and is another risk factor explaining the early mortality in ME/CFS due to cardiovascular disorder[1] (Abstract)
- 2016, Ubiquinol-10 supplementation improves autonomic nervous function and cognitive function in chronic fatigue syndrome[3] (Abstract)
Learn more[edit | edit source]
See also[edit | edit source]
References[edit | edit source]
- ↑ 1.0 1.1 Maes, M; Mihaylova, I; Kubera, M; Uytterhoeven, M; Vrydags, N; Bosmans, E (2009), "Coenzyme Q10 deficiency in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is related to fatigue, autonomic and neurocognitive symptoms and is another risk factor explaining the early mortality in ME/CFS due to cardiovascular disorder", Neuro Endocrinology Letters, 30 (4): 470–476, PMID 20010505
- ↑ 2.0 2.1 Werbach, MR (April 2000). "Nutritional strategies for treating chronic fatigue syndrome". Alternative medicine review : a journal of clinical therapeutic. 5 (2): 93–108. ISSN 1089-5159.
- ↑ 3.0 3.1 Fukuda, S; Nojima, J; Kajimoto, O; Yamaguti, K; Nakatomi, Y; Kuratsune, H; Watanabe, Y (April 29, 2016), "Ubiquinol-10 supplementation improves autonomic nervous function and cognitive function in chronic fatigue syndrome", BioFactors (Oxford, England), doi:10.1002/biof.1293, PMID 27125909