ME/CFS

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What is ME/CFS By Open Medicine Foundation - OMF. Linda Tannenbaum, Founder & CEO/President, talks about ME/CFS and how OMF is leading research and delivering hope (2018)
The acronym ME/CFS is commonly used as an umbrella term to cover the various case definitions employed to describe myalgic encephalomyelitis (ME) and/or chronic fatigue syndrome (CFS). Case definitions vary widely, with some being so broad as to cover numerous unrelated illnesses.[1] Even among the narrower case definitions, it is unclear if ME is equivalent to CFS, is a specific form of it, or something entirely different. In ME/CFS research, the terms are often used synonymously, though there is no clear evidence to support either equating them or separating them.

ME was the original name for CFS; the names are used interchangeably or with the acronym ME/CFS.[2]United States (US) government bodies now use the acronym.[3] The US Centers for Disease Control and Prevention's (CDC) website page is Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).[4] The acronym CFS/ME is used by the National Health Service (NHS) in the United Kingdom.[5] The CDC recognizes ME/CFS as a "disabling and complex disease"[6] 

"The most common overlapping condition with ME/CFS is fibromyalgia."[7][8] While some have posited ME/CFS and fibromyalgia are variants of the same illness, Benjamin Natelson, MD summoned considerable amounts of data that suggest the two illnesses differ with different pathophysiologic processes leading to different treatments.[9]

See also[edit | edit source]

Case definitions for ME/CFS

  • Canadian Consensus Criteria (CCC)[10] A diagnosis of moderate and severe forms of ME/CFS are accurately made using this criterion. Adults can be diagnosed at 6 months while pediatric cases are diagnosed at three months.

Case definition for ME

Learn more[edit | edit source]

Persons living with ME/CFS

References[edit | edit source]

  1. "What is Chronic Fatigue Syndrome & Myalgic Encephalomyelitis? - Prohealth". Prohealth. Retrieved Aug 11, 2018. 
  2. Dellwo, Adrienne (Nov 24, 2018). "Myalgic Encephalomyelitis or Chronic Fatigue Syndrome". Verywell Health. Retrieved Nov 28, 2018. 
  3. "Biomarker Research Advances in 'Chronic Fatigue Syndrome". Medscape.com. Nov 8, 2016. Retrieved Feb 7, 2019. The condition, now called myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) by US government bodies, 
  4. "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) | Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) | CDC". www.cdc.gov. Jul 3, 2018. Retrieved Sep 7, 2018. 
  5. "Chronic fatigue syndrome (CFS/ME)". nhs.uk. Retrieved Aug 13, 2018. 
  6. "What is ME/CFS? | Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) | CDC". www.cdc.gov. Jan 18, 2019. Retrieved Apr 12, 2019. 
  7. "Overlapping Conditions - American Myalgic Encephalomyelitis and Chronic Fatigue Syndrome Society". ammes.org. Retrieved Aug 12, 2018. 
  8. Jason, Leonard; Taylor, R.R.; Kennedy, C.L.; Song, S; Johnson, D; Torres, S.R. (Jan 1, 2001). "Chronic fatigue syndrome: Comorbidity with fibromyalgia and psychiatric illness". Medicine and Psychiatry. 4: 29–34. 
  9. Natelson, Benjamin H. (Feb 19, 2019). "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Fibromyalgia: Definitions, Similarities, and Differences". Clinical Therapeutics. 0 (0). doi:10.1016/j.clinthera.2018.12.016. ISSN 0149-2918. PMID 30795933. 
  10. Carruthers, Bruce M.; Jain, Anil Kumar; De Meirleir, Kenny L.; Peterson, Daniel L.; Klimas, Nancy G.; Lerner, A. Martin; Bested, Alison C.; Flor-Henry, Pierre; Joshi, Pradip; Powles, A C Peter; Sherkey, Jeffrey A.; van de Sande, Marjorie I. (2003), "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols" (PDF), Journal of Chronic Fatigue Syndrome, 11 (2): 7-115, doi:10.1300/J092v11n01_02 
  11. Clayton, Ellen Wright; Alegria, Margarita; Bateman, Lucinda; Chu, Lily; Cleeland, Charles; Davis, Ronald; Diamond, Betty; Ganiats, Theodore; Keller, Betsy; Klimas, Nancy; Lerner, A Martin; Mulrow, Cynthia; Natelson, Benjamin; Rowe, Peter; Shelanski, Michael (2015). "Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome - Redefining an Illness" (PDF). nationacademies.org. 
  12. Carruthers, Bruce M.; van de Sande, Marjorie I.; De Meirleir, Kenny L.; Klimas, Nancy G.; Broderick, Gordon; Mitchell, Terry; Staines, Donald; Powles, A. C. Peter; Speight, Nigel; Vallings, Rosamund; Bateman, Lucinda; Baumgarten-Austrheim, Barbara; Bell, David; Carlo-Stella, Nicoletta; Chia, John; Darragh, Austin; Jo, Daehyun; Lewis, Donald; Light, Alan; Marshall-Gradisnik, Sonya; Mena, Ismael; Mikovits, Judy; Miwa, Kunihisa; Murovska, Modra; Pall, Martin; Stevens, Staci (Aug 22, 2011). "Myalgic encephalomyelitis: International Consensus Criteria". Journal of Internal Medicine. 270 (4): 327–338. doi:10.1111/j.1365-2796.2011.02428.x. ISSN 0954-6820. PMC 3427890Freely accessible. PMID 21777306. 

Myalgic encephalomyelitis or chronic fatigue syndrome, often used when both illnesses are considered the same.

Myalgic encephalomyelitis or M.E. has different diagnostic criteria to chronic fatigue syndrome; neurological symptoms are required but fatigue is an optional symptom.<ref name="ICP2011primer">{{Citation

Systematic Exertion Intolerance Disease. A new term with new diagnostic criteria designed to replace chronic fatigue syndrome.<ref name="IOM2015">{{citation

The information provided at this site is not intended to diagnose or treat any illness.

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.