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Cymbalta
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{{stub}} [[File:DuloxetineBox.jpg|alt=Box of duloxetine|thumb|Generic cymbalta (duloxetine)]] '''Duloxetine''', more commonly known under the brand name '''Cymbalta''' is an [[antidepressant]] drug that is also licensed for [[anxiety]] and for several different types of [[chronic pain]]. Duloxetine is also sold under the name '''Yentreve''' in some countries.<ref name="FDAoverview">{{Cite web | url = https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=090783 | title = Cymbalta overview: FDA Approved Drug Products | last = FDA|first = | authorlink = | date = | website = FDA@drugs| archive-url = | archive-date = |url-status = | access-date=2019-08-05}}</ref><ref name="FDAlabel">{{Cite web |url = https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021427s049lbl.pdf#page=32 | title = Duloxetine label | last = FDA | authorlink = | website = FDA@drugs|archive-url= | date = 2007 | url-status=|access-date=2019-08-05}}</ref><ref name="drugs">{{Cite web | url = https://www.drugs.com/duloxetine.html | title = Duloxetine: Uses, Side Effects, Dosage, Warnings | website = Drugs.com|language=en|access-date=2019-08-05}}</ref> Duloxetine is a selective-norepinephrine reuptake inhibitor antidepressant (SNRI), and was only approved in the US in 2004.<ref name="FDAlabel" /> ==Theory == Cymbalta may be useful for some symptoms of [[ME/CFS]], particularly [[pain]], as well as for any co-existing [[depression]] or [[anxiety]]. ===Chronic pain=== [[File:Duloxetine20mg.jpg|alt=2 blue capsules of duloxetine |thumb|160x160px|Duloxetine 20mg capsules]] Duloxetine is licensed for [[fibromyalgia]], [[musculoskeletal pain]], and pain caused by diabetic peripheral neuropathy (a form of nerve pain).<ref name="FDAlabel" /> ==Clinicians== ==Risks and safety== Cymbalta has been associated with very long term and problematic discontinuation symptoms, which led to a number of law suits in the United States.{{citation needed | date = 2022}} ==Costs and availability== Cymbalta/duloxetine is a prescription only drug.<ref name="drugs"/> Generic Cymbalta (duloxetine) is widely available in many countries, which has reduced costs.<ref name="drugs"/> ==Notable studies == ==See also == *[[Antidepressant]] *[[Chronic pain]] *[[Fibromyalgia]] *[[Savella]] *[[Venlafaxine]] {{Clear}} ==Learn more == *[https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=090783 Cymbalta overview - FDA] *[https://www.drugs.com/duloxetine.html Duloxetine - drugs.com] ==References == {{Reflist}} [[Category:Potential treatments]] [[Category:Serotonin-norepinephrine reuptake inhibitors]] [[Category:Analgesics]] [[Category:Antidepressants]]
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